Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2115
  Reference Plasmid   1111525849742984_bin.4__k141_300988
  Reference Plasmid Size   5306
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025380 PAFLKHML_00002 1326 3 Skin 0.60 protein_coding synonymous_variant LOW 21C>T Ile7Ile
M0025381 PAFLKHML_00002 1504 3 Skin 0.60 protein_coding missense_variant MODERATE 199C>T Leu67Phe
M0025382 PAFLKHML_00002 1660 3 Skin 0.60 protein_coding synonymous_variant LOW 355C>T Leu119Leu
M0025383 PAFLKHML_00002 1734 3 Skin 0.60 protein_coding synonymous_variant LOW 429C>T Asn143Asn
M0025384 PAFLKHML_00002 1738 3 Skin 0.60 protein_coding missense_variant MODERATE 433C>T Leu145Phe
M0025385 PAFLKHML_00002 1740 3 Skin 0.60 protein_coding synonymous_variant LOW 435T>G Leu145Leu
M0025386 PAFLKHML_00002 1755 3 Skin 0.60 protein_coding synonymous_variant LOW 450T>G Pro150Pro
M0025387 PAFLKHML_00002 1854 3 Skin 0.60 protein_coding synonymous_variant LOW 549C>T His183His
M0025388 PAFLKHML_00002 1927 3 Skin 0.60 protein_coding synonymous_variant LOW 622T>C Leu208Leu
M0025389 PAFLKHML_00002 2385 3 Skin 0.60 protein_coding synonymous_variant LOW 1080G>A Lys360Lys
M0025390 PAFLKHML_00002 2386 3 Skin 0.60 protein_coding synonymous_variant LOW 1081T>C Leu361Leu
M0025391 PAFLKHML_00002 2412 3 Skin 0.60 protein_coding synonymous_variant LOW 1107T>C Gly369Gly
M0025392 PAFLKHML_00002 2448 3 Skin 0.60 protein_coding synonymous_variant LOW 1143T>A Arg381Arg
M0025393 PAFLKHML_00002 2475 3 Skin 0.60 protein_coding synonymous_variant LOW 1170C>T Asp390Asp
M0025394 PAFLKHML_00003 2583 4 Skin 0.80 protein_coding synonymous_variant LOW 31T>C Leu11Leu
M0025395 PAFLKHML_00003 2687 4 Skin 0.80 protein_coding missense_variant MODERATE 135T>G Asp45Glu
M0025396 PAFLKHML_00003 2723 4 Skin 0.80 protein_coding synonymous_variant LOW 171C>T Gly57Gly
M0025397 PAFLKHML_00003 2826 4 Skin 0.80 protein_coding synonymous_variant LOW 274C>T Leu92Leu
M0025398 PAFLKHML_00003 2844 4 Skin 0.80 protein_coding missense_variant MODERATE 292T>G Ser98Ala
M0025399 PAFLKHML_00003 2861 4 Skin 0.80 protein_coding synonymous_variant LOW 309A>G Leu103Leu
M0025400 PAFLKHML_00003 2895 3 Skin 0.60 protein_coding missense_variant MODERATE 343C>A Pro115Thr
M0025401 PAFLKHML_00003 2939 4 Skin 0.80 protein_coding synonymous_variant LOW 387C>G Leu129Leu
M0025402 PAFLKHML_00003 2972 4 Skin 0.80 protein_coding synonymous_variant LOW 420A>G Thr140Thr
M0025403 PAFLKHML_00003 2987 3 Skin 0.60 protein_coding synonymous_variant LOW 435T>C Ser145Ser
M0025404 PAFLKHML_00003 3041 3 Skin 0.60 protein_coding synonymous_variant LOW 489G>A Glu163Glu
M0025405 PAFLKHML_00003 3143 3 Skin 0.60 protein_coding synonymous_variant LOW 591G>C Pro197Pro
M0025406 PAFLKHML_00003 3148 4 Skin 0.80 protein_coding missense_variant MODERATE 596G>A Arg199Lys
M0025407 PAFLKHML_00003 3155 4 Skin 0.80 protein_coding synonymous_variant LOW 603T>C His201His
M0025408 PAFLKHML_00003 3014 3 Skin 0.60 protein_coding synonymous_variant LOW 462C>T Gly154Gly
M0025409 PAFLKHML_00003 3015 3 Skin 0.60 protein_coding synonymous_variant LOW 463T>C Leu155Leu
M0025410 PAFLKHML_00003 3017 3 Skin 0.60 protein_coding missense_variant MODERATE 465A>C Leu155Phe
M0025411 PAFLKHML_00003 3224 3 Skin 0.60 protein_coding synonymous_variant LOW 672C>T Arg224Arg
M0025412 PAFLKHML_00003 3227 3 Skin 0.60 protein_coding synonymous_variant LOW 675T>C Thr225Thr
M0025413 PAFLKHML_00003 3380 3 Skin 0.60 protein_coding synonymous_variant LOW 828A>C Ala276Ala
M0025414 PAFLKHML_00003 3382 3 Skin 0.60 protein_coding missense_variant MODERATE 830A>G Asp277Gly
M0025415 PAFLKHML_00003 3404 3 Skin 0.60 protein_coding synonymous_variant LOW 852T>C Gly284Gly
M0025416 PAFLKHML_00003 3764 3 Skin 0.60 protein_coding synonymous_variant LOW 1212G>A Ser404Ser
M0025417 PAFLKHML_00003 3806 3 Skin 0.60 protein_coding missense_variant MODERATE 1254C>A His418Gln
M0025418 PAFLKHML_00003 3824 3 Skin 0.60 protein_coding synonymous_variant LOW 1272C>G Thr424Thr
M0025419 PAFLKHML_00003 3857 3 Skin 0.60 protein_coding synonymous_variant LOW 1305A>G Leu435Leu
M0025420 PAFLKHML_00003 3941 3 Skin 0.60 protein_coding synonymous_variant LOW 1389T>C His463His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term