Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2116
  Reference Plasmid   1111525849742984_bin.4__k141_660893
  Reference Plasmid Size   5334
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025421 DEGIHMAI_00001 832 4 Skin 0.67 protein_coding synonymous_variant LOW 690A>T Thr230Thr
M0025422 DEGIHMAI_00003 3479 6 Skin 1.00 protein_coding missense_variant MODERATE 295A>C Asn99His
M0025423 DEGIHMAI_00001 511 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *105C>T None
M0025424 DEGIHMAI_00001 550 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *66C>T None
M0025425 DEGIHMAI_00001 566 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *50T>C None
M0025426 DEGIHMAI_00001 637 3 Skin 0.50 protein_coding synonymous_variant LOW 885T>C Ile295Ile
M0025427 DEGIHMAI_00001 694 3 Skin 0.50 protein_coding synonymous_variant LOW 828T>C Ala276Ala
M0025428 DEGIHMAI_00001 859 3 Skin 0.50 protein_coding synonymous_variant LOW 663A>G Leu221Leu
M0025429 DEGIHMAI_00001 874 3 Skin 0.50 protein_coding synonymous_variant LOW 648T>A Thr216Thr
M0025430 DEGIHMAI_00001 886 3 Skin 0.50 protein_coding missense_variant MODERATE 636A>T Glu212Asp
M0025431 DEGIHMAI_00001 937 3 Skin 0.50 protein_coding synonymous_variant LOW 585T>C Ser195Ser
M0025432 DEGIHMAI_00001 1231 3 Skin 0.50 protein_coding synonymous_variant LOW 291C>T Asn97Asn
M0025433 DEGIHMAI_00001 1577 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -56A>T None
M0025434 DEGIHMAI_00001 1616 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -95T>C None
M0025435 DEGIHMAI_00001 1622 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -101C>A None
M0025436 DEGIHMAI_00002 2028 3 Skin 0.50 protein_coding synonymous_variant LOW 1281T>C Asp427Asp
M0025437 DEGIHMAI_00002 2109 4 Skin 0.67 protein_coding synonymous_variant LOW 1200T>C Ser400Ser
M0025438 DEGIHMAI_00002 2110 4 Skin 0.67 protein_coding missense_variant MODERATE 1199G>A Ser400Asn
M0025439 DEGIHMAI_00002 2208 3 Skin 0.50 protein_coding synonymous_variant LOW 1101C>T Arg367Arg
M0025440 DEGIHMAI_00002 2379 4 Skin 0.67 protein_coding synonymous_variant LOW 930C>T Val310Val
M0025441 DEGIHMAI_00002 2394 4 Skin 0.67 protein_coding synonymous_variant LOW 915C>A Ala305Ala
M0025442 DEGIHMAI_00002 2493 3 Skin 0.50 protein_coding synonymous_variant LOW 816T>C Ile272Ile
M0025443 DEGIHMAI_00002 2505 3 Skin 0.50 protein_coding synonymous_variant LOW 804A>G Arg268Arg
M0025444 DEGIHMAI_00002 2514 3 Skin 0.50 protein_coding synonymous_variant LOW 795C>T Gly265Gly
M0025445 DEGIHMAI_00002 2624 4 Skin 0.67 protein_coding synonymous_variant LOW 685C>T Leu229Leu
M0025446 DEGIHMAI_00002 2730 3 Skin 0.50 protein_coding synonymous_variant LOW 579T>C Asn193Asn
M0025447 DEGIHMAI_00002 2808 4 Skin 0.67 protein_coding synonymous_variant LOW 501G>C Ala167Ala
M0025448 DEGIHMAI_00002 2838 4 Skin 0.67 protein_coding synonymous_variant LOW 471A>G Thr157Thr
M0025449 DEGIHMAI_00002 2844 3 Skin 0.50 protein_coding synonymous_variant LOW 465G>A Gln155Gln
M0025450 DEGIHMAI_00002 2853 4 Skin 0.67 protein_coding missense_variant MODERATE 456T>G Ile152Met
M0025451 DEGIHMAI_00002 2855 4 Skin 0.67 protein_coding missense_variant MODERATE 454A>G Ile152Val
M0025452 DEGIHMAI_00002 2874 3 Skin 0.50 protein_coding synonymous_variant LOW 435C>T Pro145Pro
M0025453 DEGIHMAI_00002 2880 3 Skin 0.50 protein_coding synonymous_variant LOW 429C>T Ala143Ala
M0025454 DEGIHMAI_00002 2883 4 Skin 0.67 protein_coding synonymous_variant LOW 426G>C Thr142Thr
M0025455 DEGIHMAI_00002 2886 4 Skin 0.67 protein_coding synonymous_variant LOW 423A>C Val141Val
M0025456 DEGIHMAI_00002 2928 4 Skin 0.67 protein_coding synonymous_variant LOW 381T>C Pro127Pro
M0025457 DEGIHMAI_00002 2931 4 Skin 0.67 protein_coding synonymous_variant LOW 378G>A Ser126Ser
M0025458 DEGIHMAI_00002 2934 4 Skin 0.67 protein_coding synonymous_variant LOW 375T>C Asn125Asn
M0025459 DEGIHMAI_00002 2937 4 Skin 0.67 protein_coding synonymous_variant LOW 372C>T Ala124Ala
M0025460 DEGIHMAI_00002 2940 4 Skin 0.67 protein_coding synonymous_variant LOW 369A>G Leu123Leu
M0025461 DEGIHMAI_00002 2955 3 Skin 0.50 protein_coding synonymous_variant LOW 354A>G Leu118Leu
M0025462 DEGIHMAI_00002 2957 3 Skin 0.50 protein_coding synonymous_variant LOW 352T>C Leu118Leu
M0025463 DEGIHMAI_00002 2958 3 Skin 0.50 protein_coding synonymous_variant LOW 351G>C Ala117Ala
M0025464 DEGIHMAI_00002 3036 4 Skin 0.67 protein_coding synonymous_variant LOW 273A>G Leu91Leu
M0025465 DEGIHMAI_00002 3125 3 Skin 0.50 protein_coding synonymous_variant LOW 184C>T Leu62Leu
M0025466 DEGIHMAI_00002 3147 4 Skin 0.67 protein_coding synonymous_variant LOW 162C>T His54His
M0025467 DEGIHMAI_00001 3407 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1886A>G None
M0025468 DEGIHMAI_00003 3519 3 Skin 0.50 protein_coding synonymous_variant LOW 255A>G Ala85Ala
M0025469 DEGIHMAI_00003 3567 4 Skin 0.67 protein_coding synonymous_variant LOW 207T>C Tyr69Tyr
M0025470 DEGIHMAI_00003 3656 4 Skin 0.67 protein_coding missense_variant MODERATE 118A>G Thr40Ala
M0025471 DEGIHMAI_00003 3675 4 Skin 0.67 protein_coding synonymous_variant LOW 99C>T His33His
M0025472 DEGIHMAI_00003 3696 3 Skin 0.50 protein_coding synonymous_variant LOW 78G>A Pro26Pro
M0025473 DEGIHMAI_00003 3712 4 Skin 0.67 protein_coding missense_variant MODERATE 62A>G Asn21Ser
M0025474 DEGIHMAI_00003 3737 3 Skin 0.50 protein_coding missense_variant MODERATE 37A>G Ser13Gly
M0025475 DEGIHMAI_00001 3794 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -2273A>G None
M0025476 DEGIHMAI_00004 3974 3 Skin 0.50 protein_coding synonymous_variant LOW 393C>T Phe131Phe
M0025477 DEGIHMAI_00004 4121 3 Skin 0.50 protein_coding synonymous_variant LOW 246C>T Pro82Pro
M0025478 DEGIHMAI_00004 4259 3 Skin 0.50 protein_coding synonymous_variant LOW 108A>G Gln36Gln
M0025479 DEGIHMAI_00001 4642 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3121A>G None
M0025480 DEGIHMAI_00001 4659 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3138T>C None
M0025481 DEGIHMAI_00005 4751 3 Skin 0.50 protein_coding missense_variant MODERATE 67T>C Phe23Leu
M0025482 DEGIHMAI_00005 4758 3 Skin 0.50 protein_coding synonymous_variant LOW 60T>A Ser20Ser
M0025483 DEGIHMAI_00001 4840 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3319G>A None
M0025484 DEGIHMAI_00001 4866 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3345A>C None
M0025485 DEGIHMAI_00001 4870 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3349G>C None
M0025486 DEGIHMAI_00001 4947 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3426C>T None
M0025487 DEGIHMAI_00001 4966 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3445C>A None
M0025488 DEGIHMAI_00006 4979 3 Skin 0.50 protein_coding splice_region_variant&stop_retained_variant LOW 350A>G Ter117Ter
M0025489 DEGIHMAI_00006 4999 3 Skin 0.50 protein_coding synonymous_variant LOW 330G>A Gln110Gln
M0025490 DEGIHMAI_00006 5035 3 Skin 0.50 protein_coding synonymous_variant LOW 294C>T Tyr98Tyr
M0025491 DEGIHMAI_00006 5047 3 Skin 0.50 protein_coding synonymous_variant LOW 282T>G Pro94Pro
M0025492 DEGIHMAI_00006 5071 3 Skin 0.50 protein_coding synonymous_variant LOW 258G>A Leu86Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term