Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2124
  Reference Plasmid   1111525849743011_bin.19_new__k141_721205
  Reference Plasmid Size   36434
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025543 LPKAFDLJ_00010 12852 3 Skin 0.04 protein_coding synonymous_variant LOW 525C>T Asp175Asp
M0025544 LPKAFDLJ_00010 12853 3 Skin 0.04 protein_coding missense_variant MODERATE 526T>G Ser176Ala
M0025545 LPKAFDLJ_00010 12855 3 Skin 0.04 protein_coding synonymous_variant LOW 528A>C Ser176Ser
M0025546 LPKAFDLJ_00010 12858 3 Skin 0.04 protein_coding synonymous_variant LOW 531T>C Arg177Arg
M0025547 LPKAFDLJ_00010 12864 3 Skin 0.04 protein_coding synonymous_variant LOW 537C>T Asn179Asn
M0025548 LPKAFDLJ_00010 12873 3 Skin 0.04 protein_coding synonymous_variant LOW 546C>G Gly182Gly
M0025549 LPKAFDLJ_00010 12882 3 Skin 0.04 protein_coding synonymous_variant LOW 555T>C Leu185Leu
M0025550 LPKAFDLJ_00010 12966 3 Skin 0.04 protein_coding synonymous_variant LOW 639A>C Arg213Arg
M0025551 LPKAFDLJ_00010 13323 20 Skin 0.29 protein_coding synonymous_variant LOW 996G>A Glu332Glu
M0025552 LPKAFDLJ_00012 15917 23 Skin 0.34 protein_coding synonymous_variant LOW 963C>T Leu321Leu
M0025553 LPKAFDLJ_00012 15929 23 Skin 0.34 protein_coding synonymous_variant LOW 975C>T Asn325Asn
M0025554 LPKAFDLJ_00017 22327 15 Skin 0.22 protein_coding missense_variant MODERATE 1309C>A Pro437Thr
M0025555 LPKAFDLJ_00017 22612 3 Skin 0.04 protein_coding missense_variant MODERATE 1594A>G Asn532Asp
M0025556 LPKAFDLJ_00017 22613 3 Skin 0.04 protein_coding missense_variant MODERATE 1595A>C Asn532Thr
M0025557 LPKAFDLJ_00017 21591 4 Skin 0.06 protein_coding synonymous_variant LOW 573C>G Gly191Gly
M0025558 LPKAFDLJ_00017 21598 4 Skin 0.06 protein_coding missense_variant MODERATE 580A>T Thr194Ser
M0025559 LPKAFDLJ_00017 21600 4 Skin 0.06 protein_coding synonymous_variant LOW 582C>G Thr194Thr
M0025560 LPKAFDLJ_00017 21622 5 Skin 0.07 protein_coding missense_variant MODERATE 604G>A Gly202Ser
M0025561 LPKAFDLJ_00017 21633 5 Skin 0.07 protein_coding synonymous_variant LOW 615A>G Ala205Ala
M0025562 LPKAFDLJ_00017 21649 5 Skin 0.07 protein_coding missense_variant MODERATE 631G>A Val211Ile
M0025563 LPKAFDLJ_00017 21678 4 Skin 0.06 protein_coding synonymous_variant LOW 660A>C Gly220Gly
M0025564 LPKAFDLJ_00003 4830 8 Skin 0.12 protein_coding synonymous_variant LOW 558A>G Ser186Ser
M0025565 LPKAFDLJ_00003 5142 8 Skin 0.12 protein_coding synonymous_variant LOW 870T>C Asn290Asn
M0025566 LPKAFDLJ_00012 16221 3 Skin 0.04 protein_coding missense_variant MODERATE 1267A>G Thr423Ala
M0025567 LPKAFDLJ_00020 27101 11 Skin 0.16 protein_coding synonymous_variant LOW 1026C>T Ser342Ser
M0025568 LPKAFDLJ_00020 27128 11 Skin 0.16 protein_coding synonymous_variant LOW 999T>C Asn333Asn
M0025569 LPKAFDLJ_00020 27141 11 Skin 0.16 protein_coding missense_variant MODERATE 986C>G Ala329Gly
M0025570 LPKAFDLJ_00020 27155 11 Skin 0.16 protein_coding synonymous_variant LOW 972G>A Leu324Leu
M0025571 LPKAFDLJ_00020 27186 11 Skin 0.16 protein_coding missense_variant MODERATE 941G>A Ser314Asn
M0025572 LPKAFDLJ_00020 27188 11 Skin 0.16 protein_coding synonymous_variant LOW 939T>C Tyr313Tyr
M0025573 LPKAFDLJ_00020 27191 11 Skin 0.16 protein_coding synonymous_variant LOW 936C>G Thr312Thr
M0025574 LPKAFDLJ_00020 27197 11 Skin 0.16 protein_coding synonymous_variant LOW 930A>G Gly310Gly
M0025575 LPKAFDLJ_00020 27209 11 Skin 0.16 protein_coding synonymous_variant LOW 918C>A Arg306Arg
M0025576 LPKAFDLJ_00020 27215 11 Skin 0.16 protein_coding synonymous_variant LOW 912C>T Ser304Ser
M0025577 LPKAFDLJ_00020 27218 11 Skin 0.16 protein_coding synonymous_variant LOW 909G>C Arg303Arg
M0025578 LPKAFDLJ_00020 27236 11 Skin 0.16 protein_coding synonymous_variant LOW 891G>A Ala297Ala
M0025579 LPKAFDLJ_00012 16025 3 Skin 0.04 protein_coding missense_variant MODERATE 1071C>A Asp357Glu
M0025580 LPKAFDLJ_00013 16364 4 Skin 0.06 protein_coding synonymous_variant LOW 330C>T Tyr110Tyr
M0025581 LPKAFDLJ_00013 16379 4 Skin 0.06 protein_coding synonymous_variant LOW 315G>A Ala105Ala
M0025582 LPKAFDLJ_00013 16414 4 Skin 0.06 protein_coding missense_variant MODERATE 280C>A Leu94Met
M0025583 LPKAFDLJ_00013 16421 4 Skin 0.06 protein_coding synonymous_variant LOW 273G>T Gly91Gly
M0025584 LPKAFDLJ_00013 16424 4 Skin 0.06 protein_coding synonymous_variant LOW 270G>A Glu90Glu
M0025585 LPKAFDLJ_00013 16429 4 Skin 0.06 protein_coding missense_variant MODERATE 265A>C Lys89Gln
M0025586 LPKAFDLJ_00013 16444 5 Skin 0.07 protein_coding missense_variant MODERATE 250G>A Asp84Asn
M0025587 LPKAFDLJ_00016 18759 3 Skin 0.04 protein_coding synonymous_variant LOW 282G>A Arg94Arg
M0025588 LPKAFDLJ_00002 2401 4 Skin 0.06 protein_coding synonymous_variant LOW 1407C>G Val469Val
M0025589 LPKAFDLJ_00002 2554 4 Skin 0.06 protein_coding synonymous_variant LOW 1254C>G Gly418Gly
M0025590 LPKAFDLJ_00002 2575 4 Skin 0.06 protein_coding synonymous_variant LOW 1233C>T Asp411Asp
M0025591 LPKAFDLJ_00002 2581 4 Skin 0.06 protein_coding synonymous_variant LOW 1227C>G Thr409Thr
M0025592 LPKAFDLJ_00002 2608 4 Skin 0.06 protein_coding synonymous_variant LOW 1200T>C Asp400Asp
M0025593 LPKAFDLJ_00002 2638 4 Skin 0.06 protein_coding synonymous_variant LOW 1170G>T Val390Val
M0025594 LPKAFDLJ_00002 2644 4 Skin 0.06 protein_coding synonymous_variant LOW 1164C>T Asn388Asn
M0025595 LPKAFDLJ_00002 2680 4 Skin 0.06 protein_coding synonymous_variant LOW 1128A>G Glu376Glu
M0025596 LPKAFDLJ_00002 2695 4 Skin 0.06 protein_coding synonymous_variant LOW 1113T>C Asp371Asp
M0025597 LPKAFDLJ_00002 2965 4 Skin 0.06 protein_coding synonymous_variant LOW 843C>T Gly281Gly
M0025598 LPKAFDLJ_00002 2983 4 Skin 0.06 protein_coding synonymous_variant LOW 825T>C Arg275Arg
M0025599 LPKAFDLJ_00014 17051 3 Skin 0.04 protein_coding synonymous_variant LOW 117A>G Arg39Arg
M0025600 LPKAFDLJ_00010 13809 3 Skin 0.04 protein_coding synonymous_variant LOW 1482T>C Ile494Ile
M0025601 LPKAFDLJ_00017 21735 3 Skin 0.04 protein_coding synonymous_variant LOW 717G>A Ala239Ala
M0025602 LPKAFDLJ_00013 16493 3 Skin 0.04 protein_coding synonymous_variant LOW 201T>C Ile67Ile
M0025603 LPKAFDLJ_00013 16535 5 Skin 0.07 protein_coding synonymous_variant LOW 159A>C Leu53Leu
M0025604 LPKAFDLJ_00020 27296 3 Skin 0.04 protein_coding missense_variant MODERATE 831C>G Asn277Lys
M0025605 LPKAFDLJ_00020 27297 3 Skin 0.04 protein_coding missense_variant MODERATE 830A>G Asn277Ser
M0025606 LPKAFDLJ_00020 27308 3 Skin 0.04 protein_coding synonymous_variant LOW 819C>T Phe273Phe
M0025607 LPKAFDLJ_00012 15959 4 Skin 0.06 protein_coding synonymous_variant LOW 1005A>C Leu335Leu
M0025608 LPKAFDLJ_00012 15968 4 Skin 0.06 protein_coding synonymous_variant LOW 1014T>C Gly338Gly
M0025609 LPKAFDLJ_00012 15974 4 Skin 0.06 protein_coding synonymous_variant LOW 1020T>C Gly340Gly
M0025610 LPKAFDLJ_00012 15975 4 Skin 0.06 protein_coding missense_variant MODERATE 1021G>A Val341Ile
M0025611 LPKAFDLJ_00012 15978 4 Skin 0.06 protein_coding missense_variant MODERATE 1024C>G Gln342Glu
M0025612 LPKAFDLJ_00012 15979 4 Skin 0.06 protein_coding missense_variant MODERATE 1025A>C Gln342Pro
M0025613 LPKAFDLJ_00012 15981 4 Skin 0.06 protein_coding missense_variant MODERATE 1027G>A Val343Ile
M0025614 LPKAFDLJ_00014 17453 3 Skin 0.04 protein_coding synonymous_variant LOW 519G>C Ala173Ala
M0025615 LPKAFDLJ_00017 24036 3 Skin 0.04 protein_coding synonymous_variant LOW 3018A>C Ile1006Ile
M0025616 LPKAFDLJ_00017 21831 3 Skin 0.04 protein_coding synonymous_variant LOW 813T>C Asp271Asp
M0025617 LPKAFDLJ_00017 21870 3 Skin 0.04 protein_coding synonymous_variant LOW 852A>G Glu284Glu
M0025618 LPKAFDLJ_00010 13173 3 Skin 0.04 protein_coding synonymous_variant LOW 846T>C Pro282Pro
M0025619 LPKAFDLJ_00010 13197 3 Skin 0.04 protein_coding synonymous_variant LOW 870T>C Arg290Arg
M0025620 LPKAFDLJ_00010 13209 3 Skin 0.04 protein_coding synonymous_variant LOW 882C>G Ala294Ala
M0025621 LPKAFDLJ_00010 13221 3 Skin 0.04 protein_coding synonymous_variant LOW 894C>G Leu298Leu
M0025622 LPKAFDLJ_00010 13260 3 Skin 0.04 protein_coding synonymous_variant LOW 933G>C Ala311Ala
M0025623 LPKAFDLJ_00010 13263 3 Skin 0.04 protein_coding synonymous_variant LOW 936G>A Arg312Arg
M0025624 LPKAFDLJ_00010 13278 3 Skin 0.04 protein_coding synonymous_variant LOW 951A>G Pro317Pro
M0025625 LPKAFDLJ_00010 13281 3 Skin 0.04 protein_coding synonymous_variant LOW 954C>G Ser318Ser
M0025626 LPKAFDLJ_00013 16874 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -181T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term