Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2128
  Reference Plasmid   1111525849743011_bin.57__k141_283511
  Reference Plasmid Size   29399
  Reference Plasmid GC Content   0.55
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025638 OMDALKAO_00020 22789 8 Skin 0.14 protein_coding synonymous_variant LOW 30G>A Thr10Thr
M0025639 OMDALKAO_00003 3108 10 Skin 0.18 protein_coding synonymous_variant LOW 417T>C Gly139Gly
M0025640 OMDALKAO_00015 18178 3 Skin 0.05 protein_coding synonymous_variant LOW 816A>G Glu272Glu
M0025641 OMDALKAO_00015 18190 3 Skin 0.05 protein_coding synonymous_variant LOW 828C>A Arg276Arg
M0025642 OMDALKAO_00015 18193 3 Skin 0.05 protein_coding synonymous_variant LOW 831C>A Ala277Ala
M0025643 OMDALKAO_00015 18199 3 Skin 0.05 protein_coding synonymous_variant LOW 837C>T Gly279Gly
M0025644 OMDALKAO_00015 18214 3 Skin 0.05 protein_coding synonymous_variant LOW 852A>G Val284Val
M0025645 OMDALKAO_00015 18220 3 Skin 0.05 protein_coding synonymous_variant LOW 858A>G Val286Val
M0025646 OMDALKAO_00015 18226 3 Skin 0.05 protein_coding synonymous_variant LOW 864G>A Leu288Leu
M0025647 OMDALKAO_00015 18250 3 Skin 0.05 protein_coding synonymous_variant LOW 888T>C Arg296Arg
M0025648 OMDALKAO_00015 18265 3 Skin 0.05 protein_coding synonymous_variant LOW 903A>G Pro301Pro
M0025649 OMDALKAO_00015 18274 3 Skin 0.05 protein_coding synonymous_variant LOW 912C>T Asp304Asp
M0025650 OMDALKAO_00015 18275 3 Skin 0.05 protein_coding synonymous_variant LOW 913C>T Leu305Leu
M0025651 OMDALKAO_00015 18283 3 Skin 0.05 protein_coding synonymous_variant LOW 921C>T Arg307Arg
M0025652 OMDALKAO_00015 18286 3 Skin 0.05 protein_coding synonymous_variant LOW 924A>G Lys308Lys
M0025653 OMDALKAO_00015 18295 3 Skin 0.05 protein_coding synonymous_variant LOW 933G>A Val311Val
M0025654 OMDALKAO_00015 18298 3 Skin 0.05 protein_coding synonymous_variant LOW 936A>G Ala312Ala
M0025655 OMDALKAO_00015 18322 3 Skin 0.05 protein_coding synonymous_variant LOW 960T>C Asn320Asn
M0025656 OMDALKAO_00015 18340 3 Skin 0.05 protein_coding synonymous_variant LOW 978C>A Ala326Ala
M0025657 OMDALKAO_00015 18343 4 Skin 0.07 protein_coding synonymous_variant LOW 981A>G Leu327Leu
M0025658 OMDALKAO_00015 18419 3 Skin 0.05 protein_coding missense_variant MODERATE 1057A>G Thr353Ala
M0025659 OMDALKAO_00015 18420 3 Skin 0.05 protein_coding missense_variant MODERATE 1058C>T Thr353Ile
M0025660 OMDALKAO_00015 18454 3 Skin 0.05 protein_coding synonymous_variant LOW 1092C>T Ser364Ser
M0025661 OMDALKAO_00015 18464 3 Skin 0.05 protein_coding synonymous_variant LOW 1102C>T Leu368Leu
M0025662 OMDALKAO_00015 18470 3 Skin 0.05 protein_coding missense_variant MODERATE 1108A>G Thr370Ala
M0025663 OMDALKAO_00015 18472 3 Skin 0.05 protein_coding synonymous_variant LOW 1110G>A Thr370Thr
M0025664 OMDALKAO_00015 18478 3 Skin 0.05 protein_coding synonymous_variant LOW 1116A>G Lys372Lys
M0025665 OMDALKAO_00015 18481 3 Skin 0.05 protein_coding synonymous_variant LOW 1119G>A Val373Val
M0025666 OMDALKAO_00019 22030 9 Skin 0.16 protein_coding missense_variant MODERATE 286C>T Pro96Ser
M0025667 OMDALKAO_00020 22828 5 Skin 0.09 protein_coding synonymous_variant LOW 69T>C Ser23Ser
M0025668 OMDALKAO_00020 22857 6 Skin 0.11 protein_coding missense_variant MODERATE 98A>G Asn33Ser
M0025669 OMDALKAO_00020 22858 6 Skin 0.11 protein_coding synonymous_variant LOW 99C>T Asn33Asn
M0025670 OMDALKAO_00020 22865 6 Skin 0.11 protein_coding missense_variant MODERATE 106A>G Asn36Asp
M0025671 OMDALKAO_00020 22918 5 Skin 0.09 protein_coding synonymous_variant LOW 159G>A Leu53Leu
M0025672 OMDALKAO_00020 22921 5 Skin 0.09 protein_coding synonymous_variant LOW 162G>T Pro54Pro
M0025673 OMDALKAO_00020 22929 5 Skin 0.09 protein_coding missense_variant MODERATE 170C>A Pro57His
M0025674 OMDALKAO_00020 22930 5 Skin 0.09 protein_coding synonymous_variant LOW 171T>C Pro57Pro
M0025675 OMDALKAO_00018 22944 5 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1229T>C None
M0025676 OMDALKAO_00018 22983 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -1268G>A None
M0025677 OMDALKAO_00011 13997 19 Skin 0.34 protein_coding synonymous_variant LOW 276C>T Gly92Gly
M0025678 OMDALKAO_00011 14003 19 Skin 0.34 protein_coding synonymous_variant LOW 270A>G Glu90Glu
M0025679 OMDALKAO_00011 14006 19 Skin 0.34 protein_coding synonymous_variant LOW 267T>C Arg89Arg
M0025680 OMDALKAO_00011 14009 19 Skin 0.34 protein_coding synonymous_variant LOW 264A>G Ala88Ala
M0025681 OMDALKAO_00011 14039 19 Skin 0.34 protein_coding synonymous_variant LOW 234A>G Val78Val
M0025682 OMDALKAO_00011 14074 19 Skin 0.34 protein_coding synonymous_variant LOW 199C>T Leu67Leu
M0025683 OMDALKAO_00011 14075 19 Skin 0.34 protein_coding synonymous_variant LOW 198G>T Val66Val
M0025684 OMDALKAO_00011 14084 19 Skin 0.34 protein_coding synonymous_variant LOW 189A>G Thr63Thr
M0025685 OMDALKAO_00011 14093 19 Skin 0.34 protein_coding synonymous_variant LOW 180C>G Arg60Arg
M0025686 OMDALKAO_00011 14141 20 Skin 0.36 protein_coding synonymous_variant LOW 132T>C Asp44Asp
M0025687 OMDALKAO_00011 14144 20 Skin 0.36 protein_coding synonymous_variant LOW 129G>C Leu43Leu
M0025688 OMDALKAO_00011 14153 20 Skin 0.36 protein_coding synonymous_variant LOW 120C>T Ile40Ile
M0025689 OMDALKAO_00011 14180 20 Skin 0.36 protein_coding missense_variant MODERATE 93T>A Asp31Glu
M0025690 OMDALKAO_00011 14192 20 Skin 0.36 protein_coding synonymous_variant LOW 81A>G Lys27Lys
M0025691 OMDALKAO_00011 14213 20 Skin 0.36 protein_coding synonymous_variant LOW 60C>T Arg20Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OMDALKAO_00010 SMZ56468.1|GH32 90.8 0 1 480 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
OMDALKAO_00021 1.B.10.1.1 75.3 2.2e-133 1 293 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.10 The Nucleoside-specific Channel-forming Outer Membrane Porin (Tsx) Family
OMDALKAO_00024 2.A.3.1.13 83.5 1.3e-214 5 447 0.9715 0.9718 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family