Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2129
  Reference Plasmid   1111525849743011_bin.57__k141_477866
  Reference Plasmid Size   17393
  Reference Plasmid GC Content   0.50
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025692 IDAIOMKN_00007 6930 3 Skin 0.20 protein_coding synonymous_variant LOW 36A>G Gln12Gln
M0025693 IDAIOMKN_00007 6939 3 Skin 0.20 protein_coding synonymous_variant LOW 45C>T Phe15Phe
M0025694 IDAIOMKN_00007 6963 3 Skin 0.20 protein_coding synonymous_variant LOW 69A>G Val23Val
M0025695 IDAIOMKN_00007 6964 3 Skin 0.20 protein_coding synonymous_variant LOW 70T>C Leu24Leu
M0025696 IDAIOMKN_00007 6969 3 Skin 0.20 protein_coding synonymous_variant LOW 75G>A Ala25Ala
M0025697 IDAIOMKN_00007 6972 3 Skin 0.20 protein_coding synonymous_variant LOW 78G>A Gln26Gln
M0025698 IDAIOMKN_00007 6996 3 Skin 0.20 protein_coding synonymous_variant LOW 102C>T Val34Val
M0025699 IDAIOMKN_00007 6999 3 Skin 0.20 protein_coding synonymous_variant LOW 105A>G Glu35Glu
M0025700 IDAIOMKN_00002 7398 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4858T>A None
M0025701 IDAIOMKN_00008 7899 6 Skin 0.40 protein_coding missense_variant MODERATE 325A>G Thr109Ala
M0025702 IDAIOMKN_00011 10506 11 Skin 0.73 protein_coding missense_variant MODERATE 454G>A Val152Ile
M0025703 IDAIOMKN_00010 12682 7 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -2775G>A None
M0025704 IDAIOMKN_00015 14834 8 Skin 0.53 protein_coding missense_variant MODERATE 1417G>A Ala473Thr
M0025705 IDAIOMKN_00010 9202 3 Skin 0.20 protein_coding missense_variant MODERATE 706G>A Gly236Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
IDAIOMKN_00002 VFG002318 Flagella 83.4 7.2e-82 1 169 1.0 1 Motility alternative sigma factor regulatory protein experiment
IDAIOMKN_00003 VFG002319 Flagella 90 1.6e-119 1 240 1.0 1 Motility flagellar biosynthesis sigma factor experiment
IDAIOMKN_00006 VFG002325 Flagella 79.4 7.8e-55 1 131 0.9632 0.9924 Motility flagellar protein FliS experiment
IDAIOMKN_00002 VFG002318 Flagella 83.4 5.4e-81 1 169 1.0 1 Motility alternative sigma factor regulatory protein prediction
IDAIOMKN_00003 VFG002319 Flagella 90 1.2e-118 1 240 1.0 1 Motility flagellar biosynthesis sigma factor prediction
IDAIOMKN_00006 VFG002325 Flagella 79.4 5.9e-54 1 131 0.9632 0.9924 Motility flagellar protein FliS prediction
IDAIOMKN_00018 VFG003445 Flagella 71.2 5.7e-33 1 104 1.0 1.0097 Motility flagellar hook-basal body complex protein FliE prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term