Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2131
  Reference Plasmid   1111525849743011_bin.6__k141_110741
  Reference Plasmid Size   13880
  Reference Plasmid GC Content   0.73
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025712 MKMBKDJC_00007 9077 6 Skin 0.21 protein_coding synonymous_variant LOW 1017C>T Arg339Arg
M0025713 MKMBKDJC_00008 10460 6 Skin 0.21 protein_coding missense_variant MODERATE 446C>T Ala149Val
M0025714 MKMBKDJC_00009 11309 8 Skin 0.29 protein_coding missense_variant MODERATE 1878T>G His626Gln
M0025715 MKMBKDJC_00009 11311 8 Skin 0.29 protein_coding missense_variant MODERATE 1876C>A His626Asn
M0025716 MKMBKDJC_00007 8360 3 Skin 0.11 protein_coding synonymous_variant LOW 1734T>G Val578Val
M0025717 MKMBKDJC_00007 8378 3 Skin 0.11 protein_coding synonymous_variant LOW 1716G>C Gly572Gly
M0025718 MKMBKDJC_00007 8384 3 Skin 0.11 protein_coding synonymous_variant LOW 1710G>C Gly570Gly
M0025719 MKMBKDJC_00007 8402 3 Skin 0.11 protein_coding synonymous_variant LOW 1692C>G Val564Val
M0025720 MKMBKDJC_00007 8453 3 Skin 0.11 protein_coding synonymous_variant LOW 1641G>C Gly547Gly
M0025721 MKMBKDJC_00009 11822 7 Skin 0.25 protein_coding synonymous_variant LOW 1365T>C Leu455Leu
M0025722 MKMBKDJC_00009 11823 7 Skin 0.25 protein_coding missense_variant MODERATE 1364T>C Leu455Pro
M0025723 MKMBKDJC_00005 6480 3 Skin 0.11 protein_coding synonymous_variant LOW 852T>C Tyr284Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term