Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2139
  Reference Plasmid   1111525849743258_bin.2__k141_2179
  Reference Plasmid Size   11981
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0027432 MOODOMPO_00010 8787 3 Skin 0.17 protein_coding missense_variant MODERATE 1018G>A Asp340Asn
M0027433 MOODOMPO_00012 10180 6 Skin 0.33 protein_coding missense_variant MODERATE 1369A>G Thr457Ala
M0027434 MOODOMPO_00004 4188 10 Skin 0.56 protein_coding missense_variant MODERATE 445G>T Ala149Ser
M0027435 MOODOMPO_00004 4358 3 Skin 0.17 protein_coding synonymous_variant LOW 615C>G Gly205Gly
M0027436 MOODOMPO_00004 4397 3 Skin 0.17 protein_coding synonymous_variant LOW 654A>G Gln218Gln
M0027437 MOODOMPO_00004 4442 3 Skin 0.17 protein_coding synonymous_variant LOW 699C>G Gly233Gly
M0027438 MOODOMPO_00005 4635 3 Skin 0.17 protein_coding synonymous_variant LOW 789A>C Ala263Ala
M0027439 MOODOMPO_00010 8248 3 Skin 0.17 protein_coding missense_variant MODERATE 479T>C Val160Ala
M0027440 MOODOMPO_00010 8252 3 Skin 0.17 protein_coding synonymous_variant LOW 483C>A Pro161Pro
M0027441 MOODOMPO_00010 8261 3 Skin 0.17 protein_coding synonymous_variant LOW 492G>C Ala164Ala
M0027442 MOODOMPO_00010 8263 3 Skin 0.17 protein_coding missense_variant MODERATE 494C>G Ala165Gly
M0027443 MOODOMPO_00010 8264 3 Skin 0.17 protein_coding synonymous_variant LOW 495A>G Ala165Ala
M0027444 MOODOMPO_00005 9268 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -3845G>A None
M0027445 MOODOMPO_00012 10144 3 Skin 0.17 protein_coding missense_variant MODERATE 1405C>T Leu469Phe
M0027446 MOODOMPO_00012 10162 3 Skin 0.17 protein_coding missense_variant MODERATE 1387G>C Ala463Pro
M0027447 MOODOMPO_00009 7321 3 Skin 0.17 protein_coding synonymous_variant LOW 189A>G Gly63Gly
M0027448 MOODOMPO_00010 8513 4 Skin 0.22 protein_coding synonymous_variant LOW 744G>A Gln248Gln
M0027449 MOODOMPO_00006 5721 4 Skin 0.22 protein_coding missense_variant MODERATE 196G>C Val66Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term