Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2164
  Reference Plasmid   1111525849743756_bin.13__k141_293385
  Reference Plasmid Size   6064
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0028797 GALEBCII_00001 853 3 Skin 0.38 protein_coding missense_variant MODERATE 754C>A Gln252Lys
M0028798 GALEBCII_00001 876 4 Skin 0.50 protein_coding synonymous_variant LOW 777C>T Val259Val
M0028799 GALEBCII_00001 1134 4 Skin 0.50 protein_coding synonymous_variant LOW 1035T>G Gly345Gly
M0028800 GALEBCII_00001 1167 4 Skin 0.50 protein_coding synonymous_variant LOW 1068T>C Arg356Arg
M0028801 GALEBCII_00002 1333 4 Skin 0.50 protein_coding missense_variant MODERATE 149A>G His50Arg
M0028802 GALEBCII_00002 1344 6 Skin 0.75 protein_coding missense_variant MODERATE 160A>G Ile54Val
M0028803 GALEBCII_00002 1349 4 Skin 0.50 protein_coding synonymous_variant LOW 165C>T Ile55Ile
M0028804 GALEBCII_00002 1526 5 Skin 0.63 protein_coding synonymous_variant LOW 342C>G Ser114Ser
M0028805 GALEBCII_00002 1544 5 Skin 0.63 protein_coding synonymous_variant LOW 360C>T Leu120Leu
M0028806 GALEBCII_00002 1565 4 Skin 0.50 protein_coding synonymous_variant LOW 381G>A Pro127Pro
M0028807 GALEBCII_00002 1578 3 Skin 0.38 protein_coding synonymous_variant LOW 394T>C Leu132Leu
M0028808 GALEBCII_00001 372 3 Skin 0.38 protein_coding synonymous_variant LOW 273T>C Phe91Phe
M0028809 GALEBCII_00001 428 3 Skin 0.38 protein_coding missense_variant MODERATE 329T>C Leu110Pro
M0028810 GALEBCII_00002 1282 3 Skin 0.38 protein_coding missense_variant MODERATE 98G>A Arg33His
M0028811 GALEBCII_00002 1394 3 Skin 0.38 protein_coding synonymous_variant LOW 210G>T Gly70Gly
M0028812 GALEBCII_00002 1402 3 Skin 0.38 protein_coding missense_variant MODERATE 218G>A Arg73Gln
M0028813 GALEBCII_00002 1748 3 Skin 0.38 protein_coding synonymous_variant LOW 564G>C Thr188Thr
M0028814 GALEBCII_00002 1778 3 Skin 0.38 protein_coding synonymous_variant LOW 594C>T Ile198Ile
M0028815 GALEBCII_00002 1985 4 Skin 0.50 protein_coding synonymous_variant LOW 801G>C Ala267Ala
M0028816 GALEBCII_00002 2037 3 Skin 0.38 protein_coding missense_variant MODERATE 853T>C Phe285Leu
M0028817 GALEBCII_00002 2066 3 Skin 0.38 protein_coding synonymous_variant LOW 882A>G Gln294Gln
M0028818 GALEBCII_00002 2081 3 Skin 0.38 protein_coding synonymous_variant LOW 897C>T Asp299Asp
M0028819 GALEBCII_00002 2120 3 Skin 0.38 protein_coding synonymous_variant LOW 936G>A Gly312Gly
M0028820 GALEBCII_00002 2324 3 Skin 0.38 protein_coding synonymous_variant LOW 1140C>T Ala380Ala
M0028821 GALEBCII_00004 3181 3 Skin 0.38 protein_coding splice_region_variant&stop_retained_variant LOW 1098A>G Ter366Ter
M0028822 GALEBCII_00004 3644 3 Skin 0.38 protein_coding missense_variant MODERATE 635A>G His212Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term