Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2166
  Reference Plasmid   1111525849743756_bin.3__k141_215679
  Reference Plasmid Size   6502
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0028889 JPCGKPOG_00007 2864 3 Skin 0.50 protein_coding missense_variant MODERATE 988C>G Gln330Glu
M0028890 JPCGKPOG_00007 3351 4 Skin 0.67 protein_coding synonymous_variant LOW 501A>C Ala167Ala
M0028891 JPCGKPOG_00007 3545 4 Skin 0.67 protein_coding missense_variant MODERATE 307C>G Gln103Glu
M0028892 JPCGKPOG_00007 3824 3 Skin 0.50 protein_coding missense_variant MODERATE 28T>C Tyr10His
M0028893 JPCGKPOG_00008 4174 5 Skin 0.83 protein_coding synonymous_variant LOW 1743A>G Ala581Ala
M0028894 JPCGKPOG_00008 4198 5 Skin 0.83 protein_coding synonymous_variant LOW 1719G>T Ala573Ala
M0028895 JPCGKPOG_00008 4228 5 Skin 0.83 protein_coding synonymous_variant LOW 1689T>C Ile563Ile
M0028896 JPCGKPOG_00008 4239 4 Skin 0.67 protein_coding missense_variant MODERATE 1678G>C Gly560Arg
M0028897 JPCGKPOG_00008 4373 5 Skin 0.83 protein_coding missense_variant MODERATE 1544G>C Gly515Ala
M0028898 JPCGKPOG_00008 4384 4 Skin 0.67 protein_coding missense_variant MODERATE 1533C>G Ile511Met
M0028899 JPCGKPOG_00008 4468 5 Skin 0.83 protein_coding synonymous_variant LOW 1449T>G Thr483Thr
M0028900 JPCGKPOG_00008 5147 3 Skin 0.50 protein_coding missense_variant MODERATE 770G>A Ser257Asn
M0028901 JPCGKPOG_00008 5347 5 Skin 0.83 protein_coding synonymous_variant LOW 570A>G Leu190Leu
M0028902 JPCGKPOG_00008 5626 3 Skin 0.50 protein_coding synonymous_variant LOW 291C>T Phe97Phe
M0028903 JPCGKPOG_00008 5644 5 Skin 0.83 protein_coding synonymous_variant LOW 273T>G Gly91Gly
M0028904 JPCGKPOG_00008 5659 3 Skin 0.50 protein_coding synonymous_variant LOW 258T>C Asp86Asp
M0028905 JPCGKPOG_00005 5994 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4338A>C None
M0028906 JPCGKPOG_00005 5996 5 Skin 0.83 protein_coding upstream_gene_variant MODIFIER -4340G>A None
M0028907 JPCGKPOG_00009 6093 3 Skin 0.50 protein_coding synonymous_variant LOW 357A>G Leu119Leu
M0028908 JPCGKPOG_00009 6176 4 Skin 0.67 protein_coding missense_variant MODERATE 274G>A Gly92Arg
M0028909 JPCGKPOG_00009 6201 5 Skin 0.83 protein_coding synonymous_variant LOW 249T>C Gly83Gly
M0028910 JPCGKPOG_00009 6215 5 Skin 0.83 protein_coding missense_variant MODERATE 235C>A Arg79Ser
M0028911 JPCGKPOG_00009 6224 5 Skin 0.83 protein_coding missense_variant MODERATE 226G>C Val76Leu
M0028912 JPCGKPOG_00009 6240 4 Skin 0.67 protein_coding synonymous_variant LOW 210C>T Thr70Thr
M0028913 JPCGKPOG_00009 6246 4 Skin 0.67 protein_coding synonymous_variant LOW 204C>T Gly68Gly
M0028914 JPCGKPOG_00006 1988 3 Skin 0.50 protein_coding synonymous_variant LOW 573G>C Val191Val
M0028915 JPCGKPOG_00006 2082 3 Skin 0.50 protein_coding missense_variant MODERATE 479G>T Arg160Leu
M0028916 JPCGKPOG_00006 2396 3 Skin 0.50 protein_coding synonymous_variant LOW 165C>G Ala55Ala
M0028917 JPCGKPOG_00006 2507 3 Skin 0.50 protein_coding synonymous_variant LOW 54G>C Thr18Thr
M0028918 JPCGKPOG_00006 2516 3 Skin 0.50 protein_coding synonymous_variant LOW 45C>T Asn15Asn
M0028919 JPCGKPOG_00006 2537 3 Skin 0.50 protein_coding synonymous_variant LOW 24G>A Glu8Glu
M0028920 JPCGKPOG_00007 3210 3 Skin 0.50 protein_coding synonymous_variant LOW 642A>G Gly214Gly
M0028921 JPCGKPOG_00007 3336 3 Skin 0.50 protein_coding synonymous_variant LOW 516T>C Ile172Ile
M0028922 JPCGKPOG_00007 3393 4 Skin 0.67 protein_coding synonymous_variant LOW 459G>C Ala153Ala
M0028923 JPCGKPOG_00008 4270 3 Skin 0.50 protein_coding synonymous_variant LOW 1647A>G Ala549Ala
M0028924 JPCGKPOG_00008 5261 3 Skin 0.50 protein_coding missense_variant MODERATE 656C>T Ser219Leu
M0028925 JPCGKPOG_00004 1315 3 Skin 0.50 protein_coding missense_variant MODERATE 607T>G Trp203Gly
M0028926 JPCGKPOG_00005 1449 3 Skin 0.50 protein_coding missense_variant MODERATE 208G>A Val70Ile
M0028927 JPCGKPOG_00005 1717 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -61T>C None
M0028928 JPCGKPOG_00009 6333 3 Skin 0.50 protein_coding synonymous_variant LOW 117C>G Arg39Arg
M0028929 JPCGKPOG_00009 6348 3 Skin 0.50 protein_coding synonymous_variant LOW 102A>G Val34Val
M0028930 JPCGKPOG_00009 6378 3 Skin 0.50 protein_coding synonymous_variant LOW 72C>T Pro24Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term