Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2167
  Reference Plasmid   1111525849743756_bin.3__k141_34137
  Reference Plasmid Size   8137
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0028931 LBHAFBEP_00001 74 3 Skin 0.43 protein_coding synonymous_variant LOW 15C>G Pro5Pro
M0028932 LBHAFBEP_00001 75 3 Skin 0.43 protein_coding missense_variant MODERATE 16C>G Pro6Ala
M0028933 LBHAFBEP_00001 80 3 Skin 0.43 protein_coding synonymous_variant LOW 21G>A Ala7Ala
M0028934 LBHAFBEP_00001 82 3 Skin 0.43 protein_coding missense_variant MODERATE 23C>T Thr8Ile
M0028935 LBHAFBEP_00001 101 5 Skin 0.71 protein_coding synonymous_variant LOW 42C>G Ala14Ala
M0028936 LBHAFBEP_00001 138 5 Skin 0.71 protein_coding missense_variant MODERATE 79G>T Ala27Ser
M0028937 LBHAFBEP_00001 252 5 Skin 0.71 protein_coding synonymous_variant LOW 193T>C Leu65Leu
M0028938 LBHAFBEP_00001 253 5 Skin 0.71 protein_coding missense_variant MODERATE 194T>C Leu65Ser
M0028939 LBHAFBEP_00003 1129 4 Skin 0.57 protein_coding synonymous_variant LOW 57G>A Ala19Ala
M0028940 LBHAFBEP_00003 1546 5 Skin 0.71 protein_coding synonymous_variant LOW 474T>C Asp158Asp
M0028941 LBHAFBEP_00003 1567 5 Skin 0.71 protein_coding synonymous_variant LOW 495C>G Val165Val
M0028942 LBHAFBEP_00003 1573 5 Skin 0.71 protein_coding synonymous_variant LOW 501A>C Gly167Gly
M0028943 LBHAFBEP_00004 2022 5 Skin 0.71 protein_coding synonymous_variant LOW 399T>G Gly133Gly
M0028944 LBHAFBEP_00004 2043 5 Skin 0.71 protein_coding synonymous_variant LOW 420C>T Gly140Gly
M0028945 LBHAFBEP_00004 2064 5 Skin 0.71 protein_coding synonymous_variant LOW 441T>C Asp147Asp
M0028946 LBHAFBEP_00004 2085 5 Skin 0.71 protein_coding synonymous_variant LOW 462T>G Ser154Ser
M0028947 LBHAFBEP_00004 2088 5 Skin 0.71 protein_coding synonymous_variant LOW 465C>G Ala155Ala
M0028948 LBHAFBEP_00004 2107 5 Skin 0.71 protein_coding missense_variant MODERATE 484C>G Arg162Gly
M0028949 LBHAFBEP_00004 2145 5 Skin 0.71 protein_coding synonymous_variant LOW 522C>T Tyr174Tyr
M0028950 LBHAFBEP_00004 2292 4 Skin 0.57 protein_coding synonymous_variant LOW 669G>C Gly223Gly
M0028951 LBHAFBEP_00004 2338 3 Skin 0.43 protein_coding missense_variant MODERATE 715A>G Thr239Ala
M0028952 LBHAFBEP_00004 2340 3 Skin 0.43 protein_coding synonymous_variant LOW 717G>C Thr239Thr
M0028953 LBHAFBEP_00004 2412 3 Skin 0.43 protein_coding synonymous_variant LOW 789C>G Arg263Arg
M0028954 LBHAFBEP_00004 2423 4 Skin 0.57 protein_coding missense_variant MODERATE 800T>C Val267Ala
M0028955 LBHAFBEP_00004 2493 4 Skin 0.57 protein_coding synonymous_variant LOW 870T>C Asp290Asp
M0028956 LBHAFBEP_00005 2604 4 Skin 0.57 protein_coding synonymous_variant LOW 483G>C Thr161Thr
M0028957 LBHAFBEP_00005 2715 4 Skin 0.57 protein_coding synonymous_variant LOW 372A>G Ala124Ala
M0028958 LBHAFBEP_00005 2746 5 Skin 0.71 protein_coding missense_variant MODERATE 341T>C Val114Ala
M0028959 LBHAFBEP_00005 2757 5 Skin 0.71 protein_coding synonymous_variant LOW 330T>C Ala110Ala
M0028960 LBHAFBEP_00005 2985 4 Skin 0.57 protein_coding synonymous_variant LOW 102C>T Tyr34Tyr
M0028961 LBHAFBEP_00005 3068 3 Skin 0.43 protein_coding synonymous_variant LOW 19T>C Leu7Leu
M0028962 LBHAFBEP_00006 3245 4 Skin 0.57 protein_coding synonymous_variant LOW 651G>T Pro217Pro
M0028963 LBHAFBEP_00006 3272 4 Skin 0.57 protein_coding synonymous_variant LOW 624G>T Val208Val
M0028964 LBHAFBEP_00006 3287 3 Skin 0.43 protein_coding synonymous_variant LOW 609C>T Pro203Pro
M0028965 LBHAFBEP_00006 3354 4 Skin 0.57 protein_coding missense_variant MODERATE 542G>A Arg181Lys
M0028966 LBHAFBEP_00006 3521 3 Skin 0.43 protein_coding synonymous_variant LOW 375T>C Asp125Asp
M0028967 LBHAFBEP_00006 3596 5 Skin 0.71 protein_coding synonymous_variant LOW 300C>G Val100Val
M0028968 LBHAFBEP_00006 3605 3 Skin 0.43 protein_coding synonymous_variant LOW 291T>C Asp97Asp
M0028969 LBHAFBEP_00006 3805 4 Skin 0.57 protein_coding synonymous_variant LOW 91T>C Leu31Leu
M0028970 LBHAFBEP_00006 3806 4 Skin 0.57 protein_coding synonymous_variant LOW 90A>G Ala30Ala
M0028971 LBHAFBEP_00007 4084 4 Skin 0.57 protein_coding synonymous_variant LOW 588T>C Thr196Thr
M0028972 LBHAFBEP_00007 4141 3 Skin 0.43 protein_coding synonymous_variant LOW 531C>A Thr177Thr
M0028973 LBHAFBEP_00007 4368 3 Skin 0.43 protein_coding missense_variant MODERATE 304C>G Pro102Ala
M0028974 LBHAFBEP_00005 4764 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -1678A>G None
M0028975 LBHAFBEP_00006 3725 3 Skin 0.43 protein_coding synonymous_variant LOW 171A>G Leu57Leu
M0028976 LBHAFBEP_00006 3803 3 Skin 0.43 protein_coding synonymous_variant LOW 93G>A Leu31Leu
M0028977 LBHAFBEP_00007 4462 3 Skin 0.43 protein_coding synonymous_variant LOW 210A>C Ala70Ala
M0028978 LBHAFBEP_00007 4503 3 Skin 0.43 protein_coding missense_variant MODERATE 169C>A Pro57Thr
M0028979 LBHAFBEP_00007 4511 3 Skin 0.43 protein_coding missense_variant MODERATE 161T>C Val54Ala
M0028980 LBHAFBEP_00008 5565 3 Skin 0.43 protein_coding synonymous_variant LOW 1332T>C Arg444Arg
M0028981 LBHAFBEP_00008 5592 3 Skin 0.43 protein_coding synonymous_variant LOW 1305T>C His435His
M0028982 LBHAFBEP_00008 6234 3 Skin 0.43 protein_coding synonymous_variant LOW 663A>G Glu221Glu
M0028983 LBHAFBEP_00005 7073 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3987G>C None
M0028984 LBHAFBEP_00005 7096 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4010G>C None
M0028985 LBHAFBEP_00009 7703 3 Skin 0.43 protein_coding synonymous_variant LOW 243T>C Pro81Pro
M0028986 LBHAFBEP_00005 2907 3 Skin 0.43 protein_coding synonymous_variant LOW 180C>G Gly60Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term