Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2168
  Reference Plasmid   1111525849743756_bin.3__k141_51421
  Reference Plasmid Size   16177
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0028987 EOCMHBII_00003 3199 3 Skin 0.33 protein_coding missense_variant MODERATE 148A>G Met50Val
M0028988 EOCMHBII_00003 3210 3 Skin 0.33 protein_coding missense_variant MODERATE 137C>T Ala46Val
M0028989 EOCMHBII_00003 3218 3 Skin 0.33 protein_coding synonymous_variant LOW 129T>C Ala43Ala
M0028990 EOCMHBII_00003 3233 3 Skin 0.33 protein_coding synonymous_variant LOW 114A>G Leu38Leu
M0028991 EOCMHBII_00004 3395 3 Skin 0.33 protein_coding synonymous_variant LOW 708T>C Arg236Arg
M0028992 EOCMHBII_00004 3806 3 Skin 0.33 protein_coding synonymous_variant LOW 297G>C Pro99Pro
M0028993 EOCMHBII_00004 3827 3 Skin 0.33 protein_coding synonymous_variant LOW 276G>A Leu92Leu
M0028994 EOCMHBII_00004 3905 3 Skin 0.33 protein_coding synonymous_variant LOW 198C>T Gly66Gly
M0028995 EOCMHBII_00001 4214 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -2390A>C None
M0028996 EOCMHBII_00005 4267 3 Skin 0.33 protein_coding synonymous_variant LOW 6T>C Thr2Thr
M0028997 EOCMHBII_00005 4480 3 Skin 0.33 protein_coding synonymous_variant LOW 219T>C Tyr73Tyr
M0028998 EOCMHBII_00005 4564 4 Skin 0.44 protein_coding synonymous_variant LOW 303A>G Gly101Gly
M0028999 EOCMHBII_00005 4897 3 Skin 0.33 protein_coding synonymous_variant LOW 636C>T Val212Val
M0029000 EOCMHBII_00005 4908 3 Skin 0.33 protein_coding missense_variant MODERATE 647C>T Ala216Val
M0029001 EOCMHBII_00005 4915 4 Skin 0.44 protein_coding synonymous_variant LOW 654G>C Pro218Pro
M0029002 EOCMHBII_00005 4981 3 Skin 0.33 protein_coding synonymous_variant LOW 720G>C Gly240Gly
M0029003 EOCMHBII_00005 4996 3 Skin 0.33 protein_coding synonymous_variant LOW 735C>G Thr245Thr
M0029004 EOCMHBII_00010 9368 3 Skin 0.33 protein_coding missense_variant MODERATE 302A>C Asp101Ala
M0029005 EOCMHBII_00011 10020 3 Skin 0.33 protein_coding synonymous_variant LOW 21T>C Asp7Asp
M0029006 EOCMHBII_00012 10873 3 Skin 0.33 protein_coding synonymous_variant LOW 762C>T Phe254Phe
M0029007 EOCMHBII_00012 10885 3 Skin 0.33 protein_coding synonymous_variant LOW 774C>T Leu258Leu
M0029008 EOCMHBII_00012 10894 3 Skin 0.33 protein_coding synonymous_variant LOW 783G>C Thr261Thr
M0029009 EOCMHBII_00012 10918 3 Skin 0.33 protein_coding synonymous_variant LOW 807G>A Ala269Ala
M0029010 EOCMHBII_00012 10933 3 Skin 0.33 protein_coding synonymous_variant LOW 822C>G Gly274Gly
M0029011 EOCMHBII_00013 12337 3 Skin 0.33 protein_coding synonymous_variant LOW 1299T>G Leu433Leu
M0029012 EOCMHBII_00013 12475 3 Skin 0.33 protein_coding synonymous_variant LOW 1437A>C Arg479Arg
M0029013 EOCMHBII_00013 12511 3 Skin 0.33 protein_coding synonymous_variant LOW 1473T>C Asn491Asn
M0029014 EOCMHBII_00013 12568 3 Skin 0.33 protein_coding synonymous_variant LOW 1530G>C Arg510Arg
M0029015 EOCMHBII_00013 12583 3 Skin 0.33 protein_coding synonymous_variant LOW 1545G>C Val515Val
M0029016 EOCMHBII_00013 12658 3 Skin 0.33 protein_coding synonymous_variant LOW 1620T>C Ile540Ile
M0029017 EOCMHBII_00013 12664 3 Skin 0.33 protein_coding synonymous_variant LOW 1626G>C Arg542Arg
M0029018 EOCMHBII_00013 12680 3 Skin 0.33 protein_coding synonymous_variant LOW 1642T>C Leu548Leu
M0029019 EOCMHBII_00013 12685 3 Skin 0.33 protein_coding synonymous_variant LOW 1647G>C Arg549Arg
M0029020 EOCMHBII_00013 12694 3 Skin 0.33 protein_coding synonymous_variant LOW 1656C>G Val552Val
M0029021 EOCMHBII_00013 12715 3 Skin 0.33 protein_coding synonymous_variant LOW 1677C>G Gly559Gly
M0029022 EOCMHBII_00013 12760 3 Skin 0.33 protein_coding synonymous_variant LOW 1722G>C Gly574Gly
M0029023 EOCMHBII_00002 2074 3 Skin 0.33 protein_coding synonymous_variant LOW 1059T>G Ala353Ala
M0029024 EOCMHBII_00002 2161 3 Skin 0.33 protein_coding synonymous_variant LOW 972A>G Val324Val
M0029025 EOCMHBII_00002 2200 3 Skin 0.33 protein_coding synonymous_variant LOW 933A>G Ala311Ala
M0029026 EOCMHBII_00002 2272 3 Skin 0.33 protein_coding synonymous_variant LOW 861G>C Ala287Ala
M0029027 EOCMHBII_00002 2290 3 Skin 0.33 protein_coding synonymous_variant LOW 843G>C Leu281Leu
M0029028 EOCMHBII_00002 2341 3 Skin 0.33 protein_coding synonymous_variant LOW 792A>C Ile264Ile
M0029029 EOCMHBII_00002 2400 3 Skin 0.33 protein_coding missense_variant MODERATE 733C>A Pro245Thr
M0029030 EOCMHBII_00002 2412 3 Skin 0.33 protein_coding synonymous_variant LOW 721T>C Leu241Leu
M0029031 EOCMHBII_00002 2649 3 Skin 0.33 protein_coding missense_variant MODERATE 484A>G Ser162Gly
M0029032 EOCMHBII_00002 2974 3 Skin 0.33 protein_coding synonymous_variant LOW 159C>T Thr53Thr
M0029033 EOCMHBII_00018 15476 3 Skin 0.33 protein_coding synonymous_variant LOW 414C>G Leu138Leu
M0029034 EOCMHBII_00018 15482 3 Skin 0.33 protein_coding missense_variant MODERATE 420G>C Met140Ile
M0029035 EOCMHBII_00019 15778 3 Skin 0.33 protein_coding synonymous_variant LOW 114C>T Gly38Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term