Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2172
  Reference Plasmid   1111525849743756_bin.7__k141_175183
  Reference Plasmid Size   2634
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029073 FBKMIGMI_00001 135 3 Skin 0.75 protein_coding synonymous_variant LOW 99T>C Asp33Asp
M0029074 FBKMIGMI_00001 177 4 Skin 1.00 protein_coding synonymous_variant LOW 141A>G Leu47Leu
M0029075 FBKMIGMI_00001 363 4 Skin 1.00 protein_coding synonymous_variant LOW 327T>G Leu109Leu
M0029076 FBKMIGMI_00001 594 3 Skin 0.75 protein_coding synonymous_variant LOW 558T>C Leu186Leu
M0029077 FBKMIGMI_00001 1137 3 Skin 0.75 protein_coding synonymous_variant LOW 1101G>C Ala367Ala
M0029078 FBKMIGMI_00001 1138 3 Skin 0.75 protein_coding missense_variant MODERATE 1102G>A Gly368Ser
M0029079 FBKMIGMI_00001 1383 4 Skin 1.00 protein_coding synonymous_variant LOW 1347C>G Leu449Leu
M0029080 FBKMIGMI_00001 1449 3 Skin 0.75 protein_coding synonymous_variant LOW 1413C>T Asp471Asp
M0029081 FBKMIGMI_00001 1455 3 Skin 0.75 protein_coding synonymous_variant LOW 1419G>C Leu473Leu
M0029082 FBKMIGMI_00001 1458 3 Skin 0.75 protein_coding synonymous_variant LOW 1422C>G Val474Val
M0029083 FBKMIGMI_00001 1461 3 Skin 0.75 protein_coding synonymous_variant LOW 1425C>G Ala475Ala
M0029084 FBKMIGMI_00001 1464 3 Skin 0.75 protein_coding synonymous_variant LOW 1428C>G Thr476Thr
M0029085 FBKMIGMI_00004 2506 3 Skin 0.75 protein_coding synonymous_variant LOW 120C>T Leu40Leu
M0029086 FBKMIGMI_00004 2574 3 Skin 0.75 protein_coding missense_variant MODERATE 52A>G Thr18Ala
M0029087 FBKMIGMI_00001 638 3 Skin 0.75 protein_coding missense_variant MODERATE 602C>G Thr201Ser
M0029088 FBKMIGMI_00001 1407 3 Skin 0.75 protein_coding synonymous_variant LOW 1371C>G Thr457Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term