Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2173
  Reference Plasmid   1111525849743756_bin.7__k141_329529
  Reference Plasmid Size   14139
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029089 HBIKDOGF_00009 9135 3 Skin 0.60 protein_coding synonymous_variant LOW 1044G>A Ala348Ala
M0029090 HBIKDOGF_00009 9768 3 Skin 0.60 protein_coding synonymous_variant LOW 1677A>G Lys559Lys
M0029091 HBIKDOGF_00009 9777 3 Skin 0.60 protein_coding synonymous_variant LOW 1686A>C Ala562Ala
M0029092 HBIKDOGF_00009 9780 3 Skin 0.60 protein_coding missense_variant MODERATE 1689A>C Glu563Asp
M0029093 HBIKDOGF_00009 9783 3 Skin 0.60 protein_coding missense_variant MODERATE 1692G>C Glu564Asp
M0029094 HBIKDOGF_00009 9784 3 Skin 0.60 protein_coding synonymous_variant LOW 1693C>T Leu565Leu
M0029095 HBIKDOGF_00009 9983 3 Skin 0.60 protein_coding missense_variant MODERATE 1892C>A Ala631Asp
M0029096 HBIKDOGF_00009 10080 3 Skin 0.60 protein_coding synonymous_variant LOW 1989C>G Val663Val
M0029097 HBIKDOGF_00009 10093 3 Skin 0.60 protein_coding missense_variant MODERATE 2002G>A Asp668Asn
M0029098 HBIKDOGF_00009 10099 3 Skin 0.60 protein_coding synonymous_variant LOW 2008C>T Leu670Leu
M0029099 HBIKDOGF_00009 10372 3 Skin 0.60 protein_coding missense_variant MODERATE 2281C>G Gln761Glu
M0029100 HBIKDOGF_00009 10566 3 Skin 0.60 protein_coding synonymous_variant LOW 2475T>G Arg825Arg
M0029101 HBIKDOGF_00009 10614 3 Skin 0.60 protein_coding synonymous_variant LOW 2523C>G Thr841Thr
M0029102 HBIKDOGF_00009 10759 3 Skin 0.60 protein_coding missense_variant MODERATE 2668A>G Asn890Asp
M0029103 HBIKDOGF_00010 11145 3 Skin 0.60 protein_coding synonymous_variant LOW 258T>C Pro86Pro
M0029104 HBIKDOGF_00010 11161 3 Skin 0.60 protein_coding missense_variant MODERATE 242G>A Gly81Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term