Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2174
  Reference Plasmid   1111525849743756_bin.9__k141_112081
  Reference Plasmid Size   165142
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029105 ANPCPPGI_00104 108644 4 Skin 0.09 protein_coding missense_variant MODERATE 29C>T Ala10Val
M0029106 ANPCPPGI_00056 56860 3 Skin 0.07 protein_coding synonymous_variant LOW 18T>C Ile6Ile
M0029107 ANPCPPGI_00057 58067 3 Skin 0.07 protein_coding synonymous_variant LOW 1114C>T Leu372Leu
M0029108 ANPCPPGI_00060 61222 6 Skin 0.14 protein_coding missense_variant MODERATE 661T>A Phe221Ile
M0029109 ANPCPPGI_00006 6027 6 Skin 0.14 protein_coding missense_variant MODERATE 2027A>T Asp676Val
M0029110 ANPCPPGI_00007 6390 6 Skin 0.14 protein_coding missense_variant MODERATE 101C>T Ala34Val
M0029111 ANPCPPGI_00023 21869 4 Skin 0.09 protein_coding missense_variant MODERATE 211G>T Ala71Ser
M0029112 ANPCPPGI_00031 31066 4 Skin 0.09 protein_coding missense_variant MODERATE 224G>A Gly75Glu
M0029113 ANPCPPGI_00032 32022 3 Skin 0.07 protein_coding synonymous_variant LOW 876C>T Ala292Ala
M0029114 ANPCPPGI_00032 32061 3 Skin 0.07 protein_coding synonymous_variant LOW 915T>C Gly305Gly
M0029115 ANPCPPGI_00145 144237 5 Skin 0.12 protein_coding synonymous_variant LOW 219T>C Ile73Ile
M0029116 ANPCPPGI_00150 151098 6 Skin 0.14 protein_coding synonymous_variant LOW 2778C>T Asp926Asp
M0029117 ANPCPPGI_00153 157177 5 Skin 0.12 protein_coding missense_variant MODERATE 340A>G Thr114Ala
M0029118 ANPCPPGI_00153 158297 5 Skin 0.12 protein_coding missense_variant MODERATE 1460G>A Arg487Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
ANPCPPGI_00040 Gold (Au), Methylene Blue [class: Thiazinium], Crystal Violet [class: Triarylmethane] 76.7 0 1 1045 0.9877 0.9905 experiment
ANPCPPGI_00043 Copper (Cu), Gold (Au) 74.3 1.19999999999999e-310 85 835 0.8919 0.9856 experiment
ANPCPPGI_00040 Gold (Au), Methylene Blue [class: Thiazinium], Crystal Violet [class: Triarylmethane] 76.8 0 1 1056 0.9981 0.9981 prediction
ANPCPPGI_00043 Copper (Cu), Gold (Au) 77.3 0 16 829 0.9667 0.9795 prediction
ANPCPPGI_00055 Mercury (Hg) 72.9 6.4e-48 4 132 0.9021 0.9214 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
ANPCPPGI_00040 ARO:3000790 76.7 0 1 1045 0.9877 0.9905 monobactam resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
ANPCPPGI_00022 QCI93939.1|GH23 100 5.15e-213 1 303 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
ANPCPPGI_00040 2.A.6.2.25 76.7 0 1 1045 0.9877 2.0775 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
ANPCPPGI_00043 3.A.3.5.20 74.3 4.5e-309 85 835 0.8919 0.9856 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily