Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2178
  Reference Plasmid   1111525849743902_bin.11_new__k141_20563
  Reference Plasmid Size   21085
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029257 FNGGBLKK_00013 9050 11 Skin 0.34 protein_coding synonymous_variant LOW 183G>T Val61Val
M0029258 FNGGBLKK_00015 12303 19 Skin 0.59 protein_coding synonymous_variant LOW 474C>G Ala158Ala
M0029259 FNGGBLKK_00016 13290 3 Skin 0.09 protein_coding synonymous_variant LOW 387C>G Ala129Ala
M0029260 FNGGBLKK_00016 13300 3 Skin 0.09 protein_coding missense_variant MODERATE 397G>A Glu133Lys
M0029261 FNGGBLKK_00006 8778 8 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4616G>C None
M0029262 FNGGBLKK_00006 8780 8 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4618C>A None
M0029263 FNGGBLKK_00006 8801 8 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4639C>G None
M0029264 FNGGBLKK_00006 8804 8 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4642C>T None
M0029265 FNGGBLKK_00006 8807 8 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4645G>A None
M0029266 FNGGBLKK_00006 8848 9 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -4686A>G None
M0029267 FNGGBLKK_00013 8878 9 Skin 0.28 protein_coding missense_variant MODERATE 11C>T Pro4Leu
M0029268 FNGGBLKK_00013 8885 9 Skin 0.28 protein_coding synonymous_variant LOW 18T>C Arg6Arg
M0029269 FNGGBLKK_00013 9076 3 Skin 0.09 protein_coding missense_variant MODERATE 209G>A Ser70Asn
M0029270 FNGGBLKK_00013 9086 3 Skin 0.09 protein_coding synonymous_variant LOW 219C>G Leu73Leu
M0029271 FNGGBLKK_00017 15972 14 Skin 0.44 protein_coding missense_variant MODERATE 1849T>G Cys617Gly
M0029272 FNGGBLKK_00013 9818 3 Skin 0.09 protein_coding synonymous_variant LOW 951C>T Asp317Asp
M0029273 FNGGBLKK_00013 9830 3 Skin 0.09 protein_coding synonymous_variant LOW 963C>A Gly321Gly
M0029274 FNGGBLKK_00017 15635 4 Skin 0.13 protein_coding synonymous_variant LOW 1512C>G Pro504Pro
M0029275 FNGGBLKK_00017 15665 4 Skin 0.13 protein_coding synonymous_variant LOW 1542C>T Ala514Ala
M0029276 FNGGBLKK_00017 15668 4 Skin 0.13 protein_coding synonymous_variant LOW 1545C>G Val515Val
M0029277 FNGGBLKK_00017 15671 4 Skin 0.13 protein_coding synonymous_variant LOW 1548T>C Gly516Gly
M0029278 FNGGBLKK_00017 15675 4 Skin 0.13 protein_coding synonymous_variant LOW 1552C>T Leu518Leu
M0029279 FNGGBLKK_00017 15677 4 Skin 0.13 protein_coding synonymous_variant LOW 1554G>C Leu518Leu
M0029280 FNGGBLKK_00017 15686 4 Skin 0.13 protein_coding synonymous_variant LOW 1563T>C Ala521Ala
M0029281 FNGGBLKK_00017 15692 4 Skin 0.13 protein_coding synonymous_variant LOW 1569C>G Gly523Gly
M0029282 FNGGBLKK_00017 15701 4 Skin 0.13 protein_coding synonymous_variant LOW 1578C>G Ala526Ala
M0029283 FNGGBLKK_00017 15719 3 Skin 0.09 protein_coding synonymous_variant LOW 1596C>A Ala532Ala
M0029284 FNGGBLKK_00017 15752 4 Skin 0.13 protein_coding synonymous_variant LOW 1629G>A Glu543Glu
M0029285 FNGGBLKK_00013 10955 3 Skin 0.09 protein_coding synonymous_variant LOW 2088A>G Glu696Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FNGGBLKK_00023 WAC22614.1|GT51 94.6 8.16e-149 3 223 0.991 0.9609





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term