Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2195
  Reference Plasmid   1111525849747079_bin.18__k141_64460
  Reference Plasmid Size   27214
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029569 ILAGIIGE_00014 14212 5 Skin 0.42 protein_coding synonymous_variant LOW 1179T>C Ala393Ala
M0029570 ILAGIIGE_00014 14257 3 Skin 0.25 protein_coding synonymous_variant LOW 1134C>T Ser378Ser
M0029571 ILAGIIGE_00014 15037 4 Skin 0.33 protein_coding synonymous_variant LOW 354G>C Thr118Thr
M0029572 ILAGIIGE_00015 15830 4 Skin 0.33 protein_coding synonymous_variant LOW 639G>A Ala213Ala
M0029573 ILAGIIGE_00015 15842 4 Skin 0.33 protein_coding synonymous_variant LOW 627C>G Ala209Ala
M0029574 ILAGIIGE_00015 15859 4 Skin 0.33 protein_coding missense_variant MODERATE 610A>C Met204Leu
M0029575 ILAGIIGE_00015 15890 4 Skin 0.33 protein_coding synonymous_variant LOW 579C>A Pro193Pro
M0029576 ILAGIIGE_00015 15938 6 Skin 0.50 protein_coding missense_variant MODERATE 531C>G His177Gln
M0029577 ILAGIIGE_00018 17536 3 Skin 0.25 protein_coding synonymous_variant LOW 1890G>A Pro630Pro
M0029578 ILAGIIGE_00018 17554 3 Skin 0.25 protein_coding synonymous_variant LOW 1872C>T Arg624Arg
M0029579 ILAGIIGE_00018 17623 4 Skin 0.33 protein_coding synonymous_variant LOW 1803G>A Gly601Gly
M0029580 ILAGIIGE_00018 17698 5 Skin 0.42 protein_coding synonymous_variant LOW 1728T>C Asp576Asp
M0029581 ILAGIIGE_00018 17764 4 Skin 0.33 protein_coding synonymous_variant LOW 1662C>T Ile554Ile
M0029582 ILAGIIGE_00018 17773 4 Skin 0.33 protein_coding synonymous_variant LOW 1653T>C Gly551Gly
M0029583 ILAGIIGE_00018 18361 3 Skin 0.25 protein_coding synonymous_variant LOW 1065C>T Ala355Ala
M0029584 ILAGIIGE_00018 18453 4 Skin 0.33 protein_coding missense_variant MODERATE 973G>C Val325Leu
M0029585 ILAGIIGE_00018 18481 3 Skin 0.25 protein_coding synonymous_variant LOW 945G>C Pro315Pro
M0029586 ILAGIIGE_00018 18493 3 Skin 0.25 protein_coding synonymous_variant LOW 933T>C Arg311Arg
M0029587 ILAGIIGE_00018 18496 3 Skin 0.25 protein_coding synonymous_variant LOW 930G>A Val310Val
M0029588 ILAGIIGE_00018 18621 7 Skin 0.58 protein_coding missense_variant MODERATE 805T>A Cys269Ser
M0029589 ILAGIIGE_00019 20329 4 Skin 0.33 protein_coding synonymous_variant LOW 957A>G Glu319Glu
M0029590 ILAGIIGE_00019 20747 6 Skin 0.50 protein_coding missense_variant MODERATE 539T>C Val180Ala
M0029591 ILAGIIGE_00006 6497 3 Skin 0.25 protein_coding synonymous_variant LOW 1524T>G Val508Val
M0029592 ILAGIIGE_00006 6773 3 Skin 0.25 protein_coding synonymous_variant LOW 1800G>A Glu600Glu
M0029593 ILAGIIGE_00006 6812 3 Skin 0.25 protein_coding synonymous_variant LOW 1839C>T Ser613Ser
M0029594 ILAGIIGE_00006 6824 3 Skin 0.25 protein_coding synonymous_variant LOW 1851T>C Ser617Ser
M0029595 ILAGIIGE_00006 6830 3 Skin 0.25 protein_coding synonymous_variant LOW 1857C>T Ile619Ile
M0029596 ILAGIIGE_00006 6836 3 Skin 0.25 protein_coding synonymous_variant LOW 1863C>G Ala621Ala
M0029597 ILAGIIGE_00006 6839 3 Skin 0.25 protein_coding synonymous_variant LOW 1866A>C Gly622Gly
M0029598 ILAGIIGE_00006 6842 3 Skin 0.25 protein_coding synonymous_variant LOW 1869A>C Arg623Arg
M0029599 ILAGIIGE_00006 6857 3 Skin 0.25 protein_coding synonymous_variant LOW 1884G>A Lys628Lys
M0029600 ILAGIIGE_00006 6860 3 Skin 0.25 protein_coding synonymous_variant LOW 1887G>C Thr629Thr
M0029601 ILAGIIGE_00009 10216 3 Skin 0.25 protein_coding synonymous_variant LOW 372T>C Asp124Asp
M0029602 ILAGIIGE_00012 12081 3 Skin 0.25 protein_coding synonymous_variant LOW 1005C>T Gly335Gly
M0029603 ILAGIIGE_00015 16157 3 Skin 0.25 protein_coding synonymous_variant LOW 312G>A Ser104Ser
M0029604 ILAGIIGE_00016 16607 3 Skin 0.25 protein_coding synonymous_variant LOW 252G>C Ala84Ala
M0029605 ILAGIIGE_00016 16631 3 Skin 0.25 protein_coding synonymous_variant LOW 228C>T Asp76Asp
M0029606 ILAGIIGE_00016 16658 3 Skin 0.25 protein_coding synonymous_variant LOW 201T>C Asn67Asn
M0029607 ILAGIIGE_00016 16687 3 Skin 0.25 protein_coding missense_variant MODERATE 172G>A Gly58Ser
M0029608 ILAGIIGE_00016 16760 5 Skin 0.42 protein_coding synonymous_variant LOW 99A>G Glu33Glu
M0029609 ILAGIIGE_00016 16766 5 Skin 0.42 protein_coding synonymous_variant LOW 93T>C Tyr31Tyr
M0029610 ILAGIIGE_00016 16787 5 Skin 0.42 protein_coding synonymous_variant LOW 72C>T Val24Val
M0029611 ILAGIIGE_00019 20857 3 Skin 0.25 protein_coding synonymous_variant LOW 429T>G Ala143Ala
M0029612 ILAGIIGE_00019 20860 3 Skin 0.25 protein_coding synonymous_variant LOW 426A>G Gln142Gln
M0029613 ILAGIIGE_00018 19083 3 Skin 0.25 protein_coding missense_variant MODERATE 343A>G Ser115Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term