Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2204
  Reference Plasmid   1111525849748616_bin.15__k141_762492
  Reference Plasmid Size   5146
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029721 MPMAMCBM_00004 3170 3 Skin 0.50 protein_coding missense_variant MODERATE 52A>G Lys18Glu
M0029722 MPMAMCBM_00005 3976 3 Skin 0.50 protein_coding synonymous_variant LOW 243G>T Ala81Ala
M0029723 MPMAMCBM_00005 3988 3 Skin 0.50 protein_coding synonymous_variant LOW 231T>C Asp77Asp
M0029724 MPMAMCBM_00005 4000 3 Skin 0.50 protein_coding synonymous_variant LOW 219C>T Asp73Asp
M0029725 MPMAMCBM_00005 4009 3 Skin 0.50 protein_coding synonymous_variant LOW 210A>G Leu70Leu
M0029726 MPMAMCBM_00005 4045 3 Skin 0.50 protein_coding synonymous_variant LOW 174T>G Ala58Ala
M0029727 MPMAMCBM_00005 4048 3 Skin 0.50 protein_coding synonymous_variant LOW 171G>A Gln57Gln
M0029728 MPMAMCBM_00005 4051 3 Skin 0.50 protein_coding synonymous_variant LOW 168T>A Val56Val
M0029729 MPMAMCBM_00005 4063 3 Skin 0.50 protein_coding missense_variant MODERATE 156A>T Glu52Asp
M0029730 MPMAMCBM_00005 4075 3 Skin 0.50 protein_coding synonymous_variant LOW 144C>G Ala48Ala
M0029731 MPMAMCBM_00005 4120 5 Skin 0.83 protein_coding synonymous_variant LOW 99A>G Ser33Ser
M0029732 MPMAMCBM_00005 4126 5 Skin 0.83 protein_coding synonymous_variant LOW 93T>C Asn31Asn
M0029733 MPMAMCBM_00005 4129 5 Skin 0.83 protein_coding synonymous_variant LOW 90T>C Asn30Asn
M0029734 MPMAMCBM_00005 4138 5 Skin 0.83 protein_coding synonymous_variant LOW 81A>G Lys27Lys
M0029735 MPMAMCBM_00005 4186 3 Skin 0.50 protein_coding synonymous_variant LOW 33C>T Gly11Gly
M0029736 MPMAMCBM_00005 4189 3 Skin 0.50 protein_coding synonymous_variant LOW 30T>C Asn10Asn
M0029737 MPMAMCBM_00005 4192 3 Skin 0.50 protein_coding synonymous_variant LOW 27C>T Ser9Ser
M0029738 MPMAMCBM_00006 4668 4 Skin 0.67 protein_coding synonymous_variant LOW 108G>A Glu36Glu
M0029739 MPMAMCBM_00006 4719 4 Skin 0.67 protein_coding missense_variant MODERATE 57G>T Lys19Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term