Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2207
  Reference Plasmid   1111525849748616_bin.21__k141_490903
  Reference Plasmid Size   46362
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0029971 NKIGFGJN_00029 34226 3 Skin 0.60 protein_coding missense_variant MODERATE 123C>A Asp41Glu
M0029972 NKIGFGJN_00027 34393 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1856T>G None
M0029973 NKIGFGJN_00027 34432 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1895C>A None
M0029974 NKIGFGJN_00030 34464 3 Skin 0.60 protein_coding synonymous_variant LOW 276C>A Pro92Pro
M0029975 NKIGFGJN_00030 34467 3 Skin 0.60 protein_coding synonymous_variant LOW 273C>G Thr91Thr
M0029976 NKIGFGJN_00030 34578 3 Skin 0.60 protein_coding synonymous_variant LOW 162A>C Pro54Pro
M0029977 NKIGFGJN_00031 34909 3 Skin 0.60 protein_coding synonymous_variant LOW 795G>C Leu265Leu
M0029978 NKIGFGJN_00031 35200 3 Skin 0.60 protein_coding synonymous_variant LOW 504G>A Gln168Gln
M0029979 NKIGFGJN_00031 35206 3 Skin 0.60 protein_coding synonymous_variant LOW 498C>A Gly166Gly
M0029980 NKIGFGJN_00031 35313 3 Skin 0.60 protein_coding missense_variant MODERATE 391C>G Arg131Gly
M0029981 NKIGFGJN_00031 35335 3 Skin 0.60 protein_coding synonymous_variant LOW 369T>C Asp123Asp
M0029982 NKIGFGJN_00031 35359 3 Skin 0.60 protein_coding synonymous_variant LOW 345C>A Gly115Gly
M0029983 NKIGFGJN_00031 35524 3 Skin 0.60 protein_coding synonymous_variant LOW 180T>C Asn60Asn
M0029984 NKIGFGJN_00031 35536 3 Skin 0.60 protein_coding synonymous_variant LOW 168C>T Asp56Asp
M0029985 NKIGFGJN_00031 35578 3 Skin 0.60 protein_coding synonymous_variant LOW 126A>C Val42Val
M0029986 NKIGFGJN_00031 35592 3 Skin 0.60 protein_coding synonymous_variant LOW 112C>T Leu38Leu
M0029987 NKIGFGJN_00032 35984 3 Skin 0.60 protein_coding synonymous_variant LOW 159C>A Thr53Thr
M0029988 NKIGFGJN_00032 36443 3 Skin 0.60 protein_coding synonymous_variant LOW 618C>A Pro206Pro
M0029989 NKIGFGJN_00032 36464 3 Skin 0.60 protein_coding synonymous_variant LOW 639C>G Val213Val
M0029990 NKIGFGJN_00032 36515 3 Skin 0.60 protein_coding synonymous_variant LOW 690G>C Ala230Ala
M0029991 NKIGFGJN_00032 36524 3 Skin 0.60 protein_coding synonymous_variant LOW 699G>T Ala233Ala
M0029992 NKIGFGJN_00032 36620 3 Skin 0.60 protein_coding synonymous_variant LOW 795T>G Pro265Pro
M0029993 NKIGFGJN_00032 36659 3 Skin 0.60 protein_coding synonymous_variant LOW 834G>T Pro278Pro
M0029994 NKIGFGJN_00032 36717 3 Skin 0.60 protein_coding missense_variant MODERATE 892C>T Pro298Ser
M0029995 NKIGFGJN_00027 36745 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4208G>A None
M0029996 NKIGFGJN_00027 36841 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4304T>A None
M0029997 NKIGFGJN_00033 37025 3 Skin 0.60 protein_coding synonymous_variant LOW 171C>T Ala57Ala
M0029998 NKIGFGJN_00033 37032 3 Skin 0.60 protein_coding missense_variant MODERATE 178C>G Leu60Val
M0029999 NKIGFGJN_00033 37037 3 Skin 0.60 protein_coding synonymous_variant LOW 183C>T Leu61Leu
M0030000 NKIGFGJN_00033 37119 3 Skin 0.60 protein_coding missense_variant MODERATE 265G>A Ala89Thr
M0030001 NKIGFGJN_00033 37127 3 Skin 0.60 protein_coding synonymous_variant LOW 273C>T His91His
M0030002 NKIGFGJN_00033 37196 3 Skin 0.60 protein_coding synonymous_variant LOW 342C>T Thr114Thr
M0030003 NKIGFGJN_00034 37381 3 Skin 0.60 protein_coding synonymous_variant LOW 96G>A Gly32Gly
M0030004 NKIGFGJN_00034 37441 3 Skin 0.60 protein_coding synonymous_variant LOW 156C>G Leu52Leu
M0030005 NKIGFGJN_00034 37460 3 Skin 0.60 protein_coding missense_variant MODERATE 175G>A Ala59Thr
M0030006 NKIGFGJN_00034 37467 3 Skin 0.60 protein_coding missense_variant MODERATE 182G>C Gly61Ala
M0030007 NKIGFGJN_00034 37507 3 Skin 0.60 protein_coding synonymous_variant LOW 222T>C Thr74Thr
M0030008 NKIGFGJN_00034 37588 3 Skin 0.60 protein_coding synonymous_variant LOW 303G>T Ala101Ala
M0030009 NKIGFGJN_00034 37673 3 Skin 0.60 protein_coding missense_variant MODERATE 388A>G Lys130Glu
M0030010 NKIGFGJN_00034 37916 3 Skin 0.60 protein_coding missense_variant MODERATE 631C>T Leu211Phe
M0030011 NKIGFGJN_00028 38123 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4321G>A None
M0030012 NKIGFGJN_00028 38155 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4353G>A None
M0030013 NKIGFGJN_00028 38251 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4449T>C None
M0030014 NKIGFGJN_00035 38380 3 Skin 0.60 protein_coding missense_variant MODERATE 118T>G Leu40Val
M0030015 NKIGFGJN_00035 38386 3 Skin 0.60 protein_coding synonymous_variant LOW 124C>T Leu42Leu
M0030016 NKIGFGJN_00035 38439 3 Skin 0.60 protein_coding synonymous_variant LOW 177A>G Glu59Glu
M0030017 NKIGFGJN_00035 38442 3 Skin 0.60 protein_coding synonymous_variant LOW 180G>A Ala60Ala
M0030018 NKIGFGJN_00036 38596 3 Skin 0.60 protein_coding synonymous_variant LOW 147C>T Val49Val
M0030019 NKIGFGJN_00036 38611 3 Skin 0.60 protein_coding synonymous_variant LOW 132C>T Asn44Asn
M0030020 NKIGFGJN_00036 38616 3 Skin 0.60 protein_coding missense_variant MODERATE 127G>C Gly43Arg
M0030021 NKIGFGJN_00036 38620 3 Skin 0.60 protein_coding synonymous_variant LOW 123C>T Leu41Leu
M0030022 NKIGFGJN_00036 38713 3 Skin 0.60 protein_coding synonymous_variant LOW 30A>G Lys10Lys
M0030023 NKIGFGJN_00037 38954 3 Skin 0.60 protein_coding synonymous_variant LOW 873C>T Phe291Phe
M0030024 NKIGFGJN_00037 39035 3 Skin 0.60 protein_coding synonymous_variant LOW 792T>C Thr264Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term