Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2214
  Reference Plasmid   1111525849751715_bin.30__k141_254901
  Reference Plasmid Size   4618
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0030063 OMEJFBMJ_00001 81 16 Skin 0.47 protein_coding synonymous_variant LOW 81T>C Leu27Leu
M0030064 OMEJFBMJ_00001 255 21 Skin 0.62 protein_coding synonymous_variant LOW 255C>T Ile85Ile
M0030065 OMEJFBMJ_00001 489 29 Skin 0.85 protein_coding synonymous_variant LOW 489A>G Gln163Gln
M0030066 OMEJFBMJ_00001 753 7 Skin 0.21 protein_coding synonymous_variant LOW 753T>C Gly251Gly
M0030067 OMEJFBMJ_00001 792 8 Skin 0.24 protein_coding synonymous_variant LOW 792A>G Glu264Glu
M0030068 OMEJFBMJ_00003 1706 26 Skin 0.76 protein_coding missense_variant MODERATE 172G>T Val58Leu
M0030069 OMEJFBMJ_00003 1777 25 Skin 0.74 protein_coding synonymous_variant LOW 243T>C Gly81Gly
M0030070 OMEJFBMJ_00003 1783 25 Skin 0.74 protein_coding synonymous_variant LOW 249C>T Gly83Gly
M0030071 OMEJFBMJ_00003 1789 25 Skin 0.74 protein_coding synonymous_variant LOW 255G>A Ala85Ala
M0030072 OMEJFBMJ_00003 2399 10 Skin 0.29 protein_coding missense_variant MODERATE 865G>A Asp289Asn
M0030073 OMEJFBMJ_00003 2458 10 Skin 0.29 protein_coding synonymous_variant LOW 924T>C Phe308Phe
M0030074 OMEJFBMJ_00003 2484 10 Skin 0.29 protein_coding missense_variant MODERATE 950A>T His317Leu
M0030075 OMEJFBMJ_00003 2608 4 Skin 0.12 protein_coding synonymous_variant LOW 1074G>T Gly358Gly
M0030076 OMEJFBMJ_00003 2896 10 Skin 0.29 protein_coding synonymous_variant LOW 1362C>G Leu454Leu
M0030077 OMEJFBMJ_00003 3020 13 Skin 0.38 protein_coding missense_variant MODERATE 1486C>T Leu496Phe
M0030078 OMEJFBMJ_00003 3036 13 Skin 0.38 protein_coding missense_variant MODERATE 1502A>C Asn501Thr
M0030079 OMEJFBMJ_00003 3064 12 Skin 0.35 protein_coding synonymous_variant LOW 1530G>C Ala510Ala
M0030080 OMEJFBMJ_00002 3548 28 Skin 0.82 protein_coding upstream_gene_variant MODIFIER -2238G>A None
M0030081 OMEJFBMJ_00004 4446 13 Skin 0.38 protein_coding synonymous_variant LOW 12G>A Thr4Thr
M0030082 OMEJFBMJ_00002 4482 13 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3172G>A None
M0030083 OMEJFBMJ_00002 4519 32 Skin 0.94 protein_coding upstream_gene_variant MODIFIER -3209G>C None
M0030084 OMEJFBMJ_00001 507 19 Skin 0.56 protein_coding synonymous_variant LOW 507T>C Ser169Ser
M0030085 OMEJFBMJ_00001 534 19 Skin 0.56 protein_coding synonymous_variant LOW 534C>G Ala178Ala
M0030086 OMEJFBMJ_00001 547 19 Skin 0.56 protein_coding missense_variant MODERATE 547C>A His183Asn
M0030087 OMEJFBMJ_00001 549 19 Skin 0.56 protein_coding synonymous_variant LOW 549C>T His183His
M0030088 OMEJFBMJ_00001 570 19 Skin 0.56 protein_coding synonymous_variant LOW 570G>C Val190Val
M0030089 OMEJFBMJ_00001 591 3 Skin 0.09 protein_coding synonymous_variant LOW 591G>C Val197Val
M0030090 OMEJFBMJ_00001 592 3 Skin 0.09 protein_coding synonymous_variant LOW 592C>T Leu198Leu
M0030091 OMEJFBMJ_00001 595 3 Skin 0.09 protein_coding synonymous_variant LOW 595C>T Leu199Leu
M0030092 OMEJFBMJ_00001 624 3 Skin 0.09 protein_coding synonymous_variant LOW 624C>T Ala208Ala
M0030093 OMEJFBMJ_00001 633 23 Skin 0.68 protein_coding synonymous_variant LOW 633C>G Pro211Pro
M0030094 OMEJFBMJ_00001 651 19 Skin 0.56 protein_coding synonymous_variant LOW 651C>T Gly217Gly
M0030095 OMEJFBMJ_00003 2020 23 Skin 0.68 protein_coding synonymous_variant LOW 486A>G Lys162Lys
M0030096 OMEJFBMJ_00003 2058 23 Skin 0.68 protein_coding missense_variant MODERATE 524C>T Ala175Val
M0030097 OMEJFBMJ_00003 2077 24 Skin 0.71 protein_coding synonymous_variant LOW 543A>G Gly181Gly
M0030098 OMEJFBMJ_00003 2212 20 Skin 0.59 protein_coding synonymous_variant LOW 678T>C Asn226Asn
M0030099 OMEJFBMJ_00003 2230 20 Skin 0.59 protein_coding synonymous_variant LOW 696C>A Ile232Ile
M0030100 OMEJFBMJ_00003 2251 20 Skin 0.59 protein_coding synonymous_variant LOW 717T>C Gly239Gly
M0030101 OMEJFBMJ_00003 3221 25 Skin 0.74 protein_coding missense_variant MODERATE 1687A>G Asn563Asp
M0030102 OMEJFBMJ_00002 4182 13 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -2872G>C None
M0030103 OMEJFBMJ_00004 4368 14 Skin 0.41 protein_coding synonymous_variant LOW 90G>A Pro30Pro
M0030104 OMEJFBMJ_00001 159 17 Skin 0.50 protein_coding synonymous_variant LOW 159T>C Phe53Phe
M0030105 OMEJFBMJ_00001 195 16 Skin 0.47 protein_coding synonymous_variant LOW 195T>C Gly65Gly
M0030106 OMEJFBMJ_00003 2143 9 Skin 0.26 protein_coding synonymous_variant LOW 609C>T Ala203Ala
M0030107 OMEJFBMJ_00003 2794 13 Skin 0.38 protein_coding synonymous_variant LOW 1260T>C Ser420Ser
M0030108 OMEJFBMJ_00003 3151 12 Skin 0.35 protein_coding synonymous_variant LOW 1617A>G Val539Val
M0030109 OMEJFBMJ_00002 3951 4 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -2641G>A None
M0030110 OMEJFBMJ_00002 4020 7 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2710A>G None
M0030111 OMEJFBMJ_00002 4542 10 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -3232A>G None
M0030112 OMEJFBMJ_00001 582 16 Skin 0.47 protein_coding synonymous_variant LOW 582C>T Arg194Arg
M0030113 OMEJFBMJ_00001 600 16 Skin 0.47 protein_coding synonymous_variant LOW 600C>T Ile200Ile
M0030114 OMEJFBMJ_00001 609 16 Skin 0.47 protein_coding synonymous_variant LOW 609C>T Ile203Ile
M0030115 OMEJFBMJ_00003 2329 11 Skin 0.32 protein_coding synonymous_variant LOW 795T>C Asp265Asp
M0030116 OMEJFBMJ_00003 2845 6 Skin 0.18 protein_coding synonymous_variant LOW 1311C>G Ser437Ser
M0030117 OMEJFBMJ_00001 447 3 Skin 0.09 protein_coding synonymous_variant LOW 447C>T Leu149Leu
M0030118 OMEJFBMJ_00001 474 3 Skin 0.09 protein_coding synonymous_variant LOW 474C>T Ser158Ser
M0030119 OMEJFBMJ_00001 486 3 Skin 0.09 protein_coding synonymous_variant LOW 486G>C Ala162Ala
M0030120 OMEJFBMJ_00003 3289 11 Skin 0.32 protein_coding synonymous_variant LOW 1755G>T Pro585Pro
M0030121 OMEJFBMJ_00003 3322 9 Skin 0.26 protein_coding synonymous_variant LOW 1788G>A Val596Val
M0030122 OMEJFBMJ_00002 3759 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2449A>G None
M0030123 OMEJFBMJ_00002 3778 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2468T>C None
M0030124 OMEJFBMJ_00002 3786 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2476A>G None
M0030125 OMEJFBMJ_00002 3787 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2477C>A None
M0030126 OMEJFBMJ_00002 3789 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2479C>G None
M0030127 OMEJFBMJ_00002 3807 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2497G>A None
M0030128 OMEJFBMJ_00002 3822 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2512G>A None
M0030129 OMEJFBMJ_00002 3855 8 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -2545G>A None
M0030130 OMEJFBMJ_00002 3870 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2560A>G None
M0030131 OMEJFBMJ_00002 3886 9 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -2576A>G None
M0030132 OMEJFBMJ_00004 4263 10 Skin 0.29 protein_coding synonymous_variant LOW 195G>A Thr65Thr
M0030133 OMEJFBMJ_00002 1095 9 Skin 0.26 protein_coding synonymous_variant LOW 216A>G Ala72Ala
M0030134 OMEJFBMJ_00003 1024 13 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -511C>G None
M0030135 OMEJFBMJ_00002 4209 7 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2899G>A None
M0030136 OMEJFBMJ_00002 4218 7 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2908G>C None
M0030137 OMEJFBMJ_00002 4224 7 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2914T>C None
M0030138 OMEJFBMJ_00001 357 3 Skin 0.09 protein_coding missense_variant MODERATE 357C>G Asp119Glu
M0030139 OMEJFBMJ_00001 372 3 Skin 0.09 protein_coding synonymous_variant LOW 372G>C Val124Val
M0030140 OMEJFBMJ_00001 684 3 Skin 0.09 protein_coding synonymous_variant LOW 684A>C Ala228Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term