Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2217
  Reference Plasmid   1111525849752591_bin.9__k141_380857
  Reference Plasmid Size   5032
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0030259 KNMAMLNE_00003 2552 4 Skin 0.44 protein_coding synonymous_variant LOW 975G>C Pro325Pro
M0030260 KNMAMLNE_00003 2792 5 Skin 0.56 protein_coding synonymous_variant LOW 1215T>G Gly405Gly
M0030261 KNMAMLNE_00003 2807 4 Skin 0.44 protein_coding synonymous_variant LOW 1230C>G Pro410Pro
M0030262 KNMAMLNE_00004 3083 7 Skin 0.78 protein_coding synonymous_variant LOW 156C>T His52His
M0030263 KNMAMLNE_00004 3902 3 Skin 0.33 protein_coding synonymous_variant LOW 975C>G Arg325Arg
M0030264 KNMAMLNE_00004 4199 5 Skin 0.56 protein_coding synonymous_variant LOW 1272C>G Ala424Ala
M0030265 KNMAMLNE_00004 4298 5 Skin 0.56 protein_coding synonymous_variant LOW 1371A>G Ala457Ala
M0030266 KNMAMLNE_00004 4337 5 Skin 0.56 protein_coding synonymous_variant LOW 1410T>C Tyr470Tyr
M0030267 KNMAMLNE_00004 4355 5 Skin 0.56 protein_coding synonymous_variant LOW 1428G>C Arg476Arg
M0030268 KNMAMLNE_00004 4358 5 Skin 0.56 protein_coding synonymous_variant LOW 1431C>T Asn477Asn
M0030269 KNMAMLNE_00004 4361 5 Skin 0.56 protein_coding synonymous_variant LOW 1434C>A Ala478Ala
M0030270 KNMAMLNE_00004 4382 5 Skin 0.56 protein_coding synonymous_variant LOW 1455G>C Pro485Pro
M0030271 KNMAMLNE_00004 4432 7 Skin 0.78 protein_coding missense_variant MODERATE 1505A>G Lys502Arg
M0030272 KNMAMLNE_00002 1374 3 Skin 0.33 protein_coding synonymous_variant LOW 81A>G Gln27Gln
M0030273 KNMAMLNE_00003 2870 3 Skin 0.33 protein_coding synonymous_variant LOW 1293G>C Gly431Gly
M0030274 KNMAMLNE_00001 2927 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -2076T>C None
M0030275 KNMAMLNE_00004 3029 3 Skin 0.33 protein_coding synonymous_variant LOW 102A>C Ala34Ala
M0030276 KNMAMLNE_00004 3031 3 Skin 0.33 protein_coding missense_variant MODERATE 104T>A Val35Glu
M0030277 KNMAMLNE_00004 3164 3 Skin 0.33 protein_coding synonymous_variant LOW 237T>C Asp79Asp
M0030278 KNMAMLNE_00004 3200 3 Skin 0.33 protein_coding synonymous_variant LOW 273C>T Ser91Ser
M0030279 KNMAMLNE_00004 3355 3 Skin 0.33 protein_coding missense_variant MODERATE 428C>T Ala143Val
M0030280 KNMAMLNE_00004 3357 3 Skin 0.33 protein_coding missense_variant MODERATE 430A>G Ser144Gly
M0030281 KNMAMLNE_00004 3362 3 Skin 0.33 protein_coding synonymous_variant LOW 435C>T His145His
M0030282 KNMAMLNE_00004 3364 3 Skin 0.33 protein_coding missense_variant MODERATE 437C>G Ala146Gly
M0030283 KNMAMLNE_00004 3377 3 Skin 0.33 protein_coding synonymous_variant LOW 450A>G Ala150Ala
M0030284 KNMAMLNE_00004 3455 3 Skin 0.33 protein_coding missense_variant MODERATE 528G>C Glu176Asp
M0030285 KNMAMLNE_00004 3458 3 Skin 0.33 protein_coding synonymous_variant LOW 531C>T Asp177Asp
M0030286 KNMAMLNE_00004 3479 3 Skin 0.33 protein_coding synonymous_variant LOW 552G>A Gln184Gln
M0030287 KNMAMLNE_00004 3493 3 Skin 0.33 protein_coding missense_variant MODERATE 566T>C Val189Ala
M0030288 KNMAMLNE_00004 3500 3 Skin 0.33 protein_coding synonymous_variant LOW 573T>C Asn191Asn
M0030289 KNMAMLNE_00004 3612 4 Skin 0.44 protein_coding missense_variant MODERATE 685G>C Ala229Pro
M0030290 KNMAMLNE_00004 3833 3 Skin 0.33 protein_coding synonymous_variant LOW 906C>G Ala302Ala
M0030291 KNMAMLNE_00003 2615 3 Skin 0.33 protein_coding synonymous_variant LOW 1038A>G Ala346Ala
M0030292 KNMAMLNE_00003 2618 3 Skin 0.33 protein_coding synonymous_variant LOW 1041A>G Lys347Lys
M0030293 KNMAMLNE_00003 2621 3 Skin 0.33 protein_coding synonymous_variant LOW 1044C>T Leu348Leu
M0030294 KNMAMLNE_00003 2624 3 Skin 0.33 protein_coding synonymous_variant LOW 1047C>G Ala349Ala
M0030295 KNMAMLNE_00003 2636 3 Skin 0.33 protein_coding synonymous_variant LOW 1059C>T Tyr353Tyr
M0030296 KNMAMLNE_00003 2642 3 Skin 0.33 protein_coding synonymous_variant LOW 1065A>G Arg355Arg
M0030297 KNMAMLNE_00003 2648 3 Skin 0.33 protein_coding synonymous_variant LOW 1071G>A Glu357Glu
M0030298 KNMAMLNE_00003 2651 3 Skin 0.33 protein_coding synonymous_variant LOW 1074T>C Asn358Asn
M0030299 KNMAMLNE_00002 1332 3 Skin 0.33 protein_coding synonymous_variant LOW 123A>G Ala41Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term