Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2226
  Reference Plasmid   1111525849753914_bin.29__k141_218150
  Reference Plasmid Size   17973
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0030481 JBBCFPNE_00002 2080 3 Skin 0.50 protein_coding missense_variant MODERATE 13G>A Ala5Thr
M0030482 JBBCFPNE_00003 2236 3 Skin 0.50 protein_coding synonymous_variant LOW 615T>C Phe205Phe
M0030483 JBBCFPNE_00005 3442 3 Skin 0.50 protein_coding missense_variant MODERATE 103A>G Ile35Val
M0030484 JBBCFPNE_00006 3811 3 Skin 0.50 protein_coding missense_variant MODERATE 712G>A Ala238Thr
M0030485 JBBCFPNE_00006 3848 3 Skin 0.50 protein_coding synonymous_variant LOW 675A>G Ala225Ala
M0030486 JBBCFPNE_00007 4808 3 Skin 0.50 protein_coding missense_variant MODERATE 917T>C Val306Ala
M0030487 JBBCFPNE_00009 6732 3 Skin 0.50 protein_coding missense_variant MODERATE 310T>C Ser104Pro
M0030488 JBBCFPNE_00009 7143 3 Skin 0.50 protein_coding missense_variant MODERATE 721A>G Thr241Ala
M0030489 JBBCFPNE_00010 7567 3 Skin 0.50 protein_coding synonymous_variant LOW 624A>C Leu208Leu
M0030490 JBBCFPNE_00011 8275 3 Skin 0.50 protein_coding missense_variant MODERATE 428G>C Gly143Ala
M0030491 JBBCFPNE_00006 8725 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4203A>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term