Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2231
  Reference Plasmid   1111525849753914_bin.29__k141_522058
  Reference Plasmid Size   48898
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0030538 HGNHAEMO_00017 22725 3 Skin 0.43 protein_coding missense_variant MODERATE 977C>A Ala326Asp
M0030539 HGNHAEMO_00017 23018 3 Skin 0.43 protein_coding synonymous_variant LOW 684C>T Asp228Asp
M0030540 HGNHAEMO_00017 23036 3 Skin 0.43 protein_coding synonymous_variant LOW 666C>G Thr222Thr
M0030541 HGNHAEMO_00017 23042 3 Skin 0.43 protein_coding synonymous_variant LOW 660C>G Gly220Gly
M0030542 HGNHAEMO_00017 23136 3 Skin 0.43 protein_coding missense_variant MODERATE 566C>T Ala189Val
M0030543 HGNHAEMO_00017 23141 3 Skin 0.43 protein_coding synonymous_variant LOW 561G>T Leu187Leu
M0030544 HGNHAEMO_00017 23153 3 Skin 0.43 protein_coding synonymous_variant LOW 549G>A Gly183Gly
M0030545 HGNHAEMO_00020 25920 3 Skin 0.43 protein_coding synonymous_variant LOW 873G>C Val291Val
M0030546 HGNHAEMO_00020 25923 3 Skin 0.43 protein_coding missense_variant MODERATE 870C>G Asp290Glu
M0030547 HGNHAEMO_00020 26367 3 Skin 0.43 protein_coding synonymous_variant LOW 426A>G Val142Val
M0030548 HGNHAEMO_00020 26403 3 Skin 0.43 protein_coding synonymous_variant LOW 390T>C Gly130Gly
M0030549 HGNHAEMO_00021 27050 3 Skin 0.43 protein_coding synonymous_variant LOW 477A>C Thr159Thr
M0030550 HGNHAEMO_00021 27185 3 Skin 0.43 protein_coding synonymous_variant LOW 342A>G Val114Val
M0030551 HGNHAEMO_00022 27812 3 Skin 0.43 protein_coding missense_variant MODERATE 892G>C Val298Leu
M0030552 HGNHAEMO_00023 29175 3 Skin 0.43 protein_coding synonymous_variant LOW 369T>C Ala123Ala
M0030553 HGNHAEMO_00024 29965 3 Skin 0.43 protein_coding synonymous_variant LOW 462C>G Ala154Ala
M0030554 HGNHAEMO_00024 30290 3 Skin 0.43 protein_coding missense_variant MODERATE 137A>G His46Arg
M0030555 HGNHAEMO_00019 30502 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4745T>C None
M0030556 HGNHAEMO_00019 30554 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4797A>G None
M0030557 HGNHAEMO_00025 30872 3 Skin 0.43 protein_coding missense_variant MODERATE 283G>C Ala95Pro
M0030558 HGNHAEMO_00025 30934 3 Skin 0.43 protein_coding synonymous_variant LOW 345C>G Ala115Ala
M0030559 HGNHAEMO_00025 31528 3 Skin 0.43 protein_coding synonymous_variant LOW 939A>G Gln313Gln
M0030560 HGNHAEMO_00025 31717 3 Skin 0.43 protein_coding synonymous_variant LOW 1128T>G Gly376Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term