Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2232
  Reference Plasmid   1111525849753914_bin.29__k141_53841
  Reference Plasmid Size   67516
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0030561 FCCNOGLA_00049 58733 3 Skin 0.10 protein_coding missense_variant MODERATE 77T>C Val26Ala
M0030562 FCCNOGLA_00049 59511 3 Skin 0.10 protein_coding synonymous_variant LOW 855C>G Pro285Pro
M0030563 FCCNOGLA_00049 59514 3 Skin 0.10 protein_coding synonymous_variant LOW 858A>G Ala286Ala
M0030564 FCCNOGLA_00018 19361 4 Skin 0.13 protein_coding missense_variant MODERATE 92A>C Glu31Ala
M0030565 FCCNOGLA_00018 19443 4 Skin 0.13 protein_coding synonymous_variant LOW 174A>C Ala58Ala
M0030566 FCCNOGLA_00018 19455 4 Skin 0.13 protein_coding synonymous_variant LOW 186C>T Val62Val
M0030567 FCCNOGLA_00018 19461 3 Skin 0.10 protein_coding synonymous_variant LOW 192C>T Pro64Pro
M0030568 FCCNOGLA_00018 19495 4 Skin 0.13 protein_coding synonymous_variant LOW 226T>C Leu76Leu
M0030569 FCCNOGLA_00022 24965 3 Skin 0.10 protein_coding synonymous_variant LOW 873G>A Glu291Glu
M0030570 FCCNOGLA_00022 24995 3 Skin 0.10 protein_coding synonymous_variant LOW 843T>C Tyr281Tyr
M0030571 FCCNOGLA_00023 26101 3 Skin 0.10 protein_coding missense_variant MODERATE 1224A>C Glu408Asp
M0030572 FCCNOGLA_00023 26932 3 Skin 0.10 protein_coding synonymous_variant LOW 393C>G Thr131Thr
M0030573 FCCNOGLA_00023 26957 3 Skin 0.10 protein_coding missense_variant MODERATE 368T>C Val123Ala
M0030574 FCCNOGLA_00024 27493 3 Skin 0.10 protein_coding missense_variant MODERATE 22A>T Ser8Cys
M0030575 FCCNOGLA_00024 27693 3 Skin 0.10 protein_coding synonymous_variant LOW 222A>G Gln74Gln
M0030576 FCCNOGLA_00024 27873 3 Skin 0.10 protein_coding synonymous_variant LOW 402A>C Ala134Ala
M0030577 FCCNOGLA_00024 27971 3 Skin 0.10 protein_coding missense_variant MODERATE 500T>C Val167Ala
M0030578 FCCNOGLA_00024 27975 3 Skin 0.10 protein_coding synonymous_variant LOW 504T>G Leu168Leu
M0030579 FCCNOGLA_00026 30126 3 Skin 0.10 protein_coding missense_variant MODERATE 119T>C Leu40Pro
M0030580 FCCNOGLA_00005 6139 3 Skin 0.10 protein_coding synonymous_variant LOW 351T>C Phe117Phe
M0030581 FCCNOGLA_00006 6968 3 Skin 0.10 protein_coding missense_variant MODERATE 517A>G Thr173Ala
M0030582 FCCNOGLA_00016 17105 3 Skin 0.10 protein_coding missense_variant MODERATE 148C>T Pro50Ser
M0030583 FCCNOGLA_00011 11639 3 Skin 0.10 protein_coding synonymous_variant LOW 570T>C Gly190Gly
M0030584 FCCNOGLA_00033 41597 3 Skin 0.10 protein_coding synonymous_variant LOW 576T>G Ser192Ser
M0030585 FCCNOGLA_00033 41626 3 Skin 0.10 protein_coding missense_variant MODERATE 547C>T Leu183Phe
M0030586 FCCNOGLA_00034 42710 3 Skin 0.10 protein_coding synonymous_variant LOW 918T>C Leu306Leu
M0030587 FCCNOGLA_00034 42749 3 Skin 0.10 protein_coding synonymous_variant LOW 879C>T Asp293Asp
M0030588 FCCNOGLA_00034 42788 3 Skin 0.10 protein_coding synonymous_variant LOW 840T>C Gly280Gly
M0030589 FCCNOGLA_00034 43036 3 Skin 0.10 protein_coding synonymous_variant LOW 592C>T Leu198Leu
M0030590 FCCNOGLA_00034 43171 3 Skin 0.10 protein_coding missense_variant MODERATE 457G>A Val153Ile
M0030591 FCCNOGLA_00034 43346 3 Skin 0.10 protein_coding synonymous_variant LOW 282A>C Val94Val
M0030592 FCCNOGLA_00036 46845 3 Skin 0.10 protein_coding missense_variant MODERATE 140T>C Val47Ala
M0030593 FCCNOGLA_00037 47834 3 Skin 0.10 protein_coding synonymous_variant LOW 669A>G Glu223Glu
M0030594 FCCNOGLA_00037 48304 3 Skin 0.10 protein_coding missense_variant MODERATE 1139A>C His380Pro
M0030595 FCCNOGLA_00038 48472 3 Skin 0.10 protein_coding missense_variant MODERATE 559A>G Lys187Glu
M0030596 FCCNOGLA_00030 37373 3 Skin 0.10 protein_coding synonymous_variant LOW 810A>G Ala270Ala
M0030597 FCCNOGLA_00030 37406 4 Skin 0.13 protein_coding synonymous_variant LOW 777G>C Thr259Thr
M0030598 FCCNOGLA_00031 38410 3 Skin 0.10 protein_coding synonymous_variant LOW 120C>G Ala40Ala
M0030599 FCCNOGLA_00032 39027 3 Skin 0.10 protein_coding synonymous_variant LOW 1929T>C Gly643Gly
M0030600 FCCNOGLA_00043 53950 3 Skin 0.10 protein_coding missense_variant MODERATE 73C>G Pro25Ala
M0030601 FCCNOGLA_00045 55993 3 Skin 0.10 protein_coding synonymous_variant LOW 585G>C Val195Val
M0030602 FCCNOGLA_00045 56179 3 Skin 0.10 protein_coding synonymous_variant LOW 399A>C Gly133Gly
M0030603 FCCNOGLA_00002 4577 3 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -1631A>G None
M0030604 FCCNOGLA_00002 4744 3 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -1798A>G None
M0030605 FCCNOGLA_00001 527 3 Skin 0.10 protein_coding missense_variant MODERATE 388A>G Ile130Val
M0030606 FCCNOGLA_00002 829 3 Skin 0.10 protein_coding synonymous_variant LOW 2118T>C Arg706Arg
M0030607 FCCNOGLA_00002 948 3 Skin 0.10 protein_coding missense_variant MODERATE 1999T>C Phe667Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term