Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2237
  Reference Plasmid   1111525849753914_bin.29__k141_73632
  Reference Plasmid Size   44295
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0030630 KBMNNLOL_00018 19577 4 Skin 0.31 protein_coding synonymous_variant LOW 21T>C His7His
M0030631 KBMNNLOL_00019 20525 3 Skin 0.23 protein_coding missense_variant MODERATE 363T>G Cys121Trp
M0030632 KBMNNLOL_00019 20957 3 Skin 0.23 protein_coding synonymous_variant LOW 795T>C Ile265Ile
M0030633 KBMNNLOL_00019 21171 3 Skin 0.23 protein_coding synonymous_variant LOW 1009C>T Leu337Leu
M0030634 KBMNNLOL_00010 10932 3 Skin 0.23 protein_coding missense_variant MODERATE 142G>C Ala48Pro
M0030635 KBMNNLOL_00010 10973 3 Skin 0.23 protein_coding synonymous_variant LOW 183T>C Ile61Ile
M0030636 KBMNNLOL_00010 11021 3 Skin 0.23 protein_coding synonymous_variant LOW 231C>T Arg77Arg
M0030637 KBMNNLOL_00011 12115 3 Skin 0.23 protein_coding synonymous_variant LOW 138T>G Leu46Leu
M0030638 KBMNNLOL_00011 12847 3 Skin 0.23 protein_coding synonymous_variant LOW 870T>G Ala290Ala
M0030639 KBMNNLOL_00011 13046 3 Skin 0.23 protein_coding missense_variant MODERATE 1069T>C Ser357Pro
M0030640 KBMNNLOL_00012 13194 3 Skin 0.23 protein_coding synonymous_variant LOW 129G>A Ser43Ser
M0030641 KBMNNLOL_00012 13215 3 Skin 0.23 protein_coding synonymous_variant LOW 150C>T Gly50Gly
M0030642 KBMNNLOL_00013 14749 3 Skin 0.23 protein_coding synonymous_variant LOW 763C>T Leu255Leu
M0030643 KBMNNLOL_00013 14766 3 Skin 0.23 protein_coding synonymous_variant LOW 780G>A Val260Val
M0030644 KBMNNLOL_00013 14811 3 Skin 0.23 protein_coding synonymous_variant LOW 825G>A Glu275Glu
M0030645 KBMNNLOL_00014 14932 3 Skin 0.23 protein_coding synonymous_variant LOW 1320A>G Lys440Lys
M0030646 KBMNNLOL_00017 19233 3 Skin 0.23 protein_coding missense_variant MODERATE 20A>G Lys7Arg
M0030647 KBMNNLOL_00017 19376 3 Skin 0.23 protein_coding missense_variant MODERATE 163A>G Met55Val
M0030648 KBMNNLOL_00018 19653 3 Skin 0.23 protein_coding missense_variant MODERATE 97G>A Ala33Thr
M0030649 KBMNNLOL_00018 19691 3 Skin 0.23 protein_coding synonymous_variant LOW 135T>C Asp45Asp
M0030650 KBMNNLOL_00018 19703 3 Skin 0.23 protein_coding synonymous_variant LOW 147C>T Gly49Gly
M0030651 KBMNNLOL_00018 19709 3 Skin 0.23 protein_coding missense_variant MODERATE 153C>A His51Gln
M0030652 KBMNNLOL_00018 19738 3 Skin 0.23 protein_coding missense_variant MODERATE 182T>C Ile61Thr
M0030653 KBMNNLOL_00014 20104 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -3853T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term