Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2241
  Reference Plasmid   1111525849755503_bin.7__k141_123530
  Reference Plasmid Size   6257
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0031011 IPNIDENI_00001 125 4 Skin 0.57 protein_coding synonymous_variant LOW 114T>C Pro38Pro
M0031012 IPNIDENI_00001 146 4 Skin 0.57 protein_coding synonymous_variant LOW 135G>C Thr45Thr
M0031013 IPNIDENI_00002 478 3 Skin 0.43 protein_coding synonymous_variant LOW 78C>G Pro26Pro
M0031014 IPNIDENI_00002 559 3 Skin 0.43 protein_coding synonymous_variant LOW 159A>G Ala53Ala
M0031015 IPNIDENI_00002 745 4 Skin 0.57 protein_coding synonymous_variant LOW 345A>G Arg115Arg
M0031016 IPNIDENI_00002 858 3 Skin 0.43 protein_coding missense_variant MODERATE 458G>A Arg153His
M0031017 IPNIDENI_00002 1054 3 Skin 0.43 protein_coding synonymous_variant LOW 654A>G Ala218Ala
M0031018 IPNIDENI_00002 1441 3 Skin 0.43 protein_coding synonymous_variant LOW 1041A>G Lys347Lys
M0031019 IPNIDENI_00002 1501 3 Skin 0.43 protein_coding synonymous_variant LOW 1101G>C Ala367Ala
M0031020 IPNIDENI_00002 1534 3 Skin 0.43 protein_coding synonymous_variant LOW 1134G>C Gly378Gly
M0031021 IPNIDENI_00003 2181 3 Skin 0.43 protein_coding missense_variant MODERATE 1922C>A Ala641Glu
M0031022 IPNIDENI_00003 2372 3 Skin 0.43 protein_coding synonymous_variant LOW 1731G>C Pro577Pro
M0031023 IPNIDENI_00003 3125 3 Skin 0.43 protein_coding synonymous_variant LOW 978A>G Val326Val
M0031024 IPNIDENI_00003 3749 3 Skin 0.43 protein_coding synonymous_variant LOW 354C>G Val118Val
M0031025 IPNIDENI_00003 3752 3 Skin 0.43 protein_coding synonymous_variant LOW 351C>G Val117Val
M0031026 IPNIDENI_00003 3938 3 Skin 0.43 protein_coding synonymous_variant LOW 165A>G Thr55Thr
M0031027 IPNIDENI_00004 4421 3 Skin 0.43 protein_coding synonymous_variant LOW 210C>T Asp70Asp
M0031028 IPNIDENI_00004 4424 3 Skin 0.43 protein_coding synonymous_variant LOW 213G>T Ala71Ala
M0031029 IPNIDENI_00004 4583 3 Skin 0.43 protein_coding synonymous_variant LOW 372A>C Ile124Ile
M0031030 IPNIDENI_00004 4611 3 Skin 0.43 protein_coding synonymous_variant LOW 400A>C Arg134Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term