Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C17
  Reference Plasmid   1111525849755644_bin.43__k141_120221
  Reference Plasmid Size   9188
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0031585 FNNAPPJD_00008 5997 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -246G>A None
M0031586 FNNAPPJD_00009 6574 3 Skin 1.00 protein_coding missense_variant MODERATE 46T>G Phe16Val
M0031587 FNNAPPJD_00009 6592 3 Skin 1.00 protein_coding missense_variant MODERATE 28A>G Thr10Ala
M0031588 FNNAPPJD_00008 6670 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -919G>A None
M0031589 FNNAPPJD_00010 6774 3 Skin 1.00 protein_coding missense_variant MODERATE 16C>A His6Asn
M0031590 FNNAPPJD_00010 6797 3 Skin 1.00 protein_coding synonymous_variant LOW 39A>T Ala13Ala
M0031591 FNNAPPJD_00010 7097 3 Skin 1.00 protein_coding synonymous_variant LOW 339G>A Gly113Gly
M0031592 FNNAPPJD_00010 7124 3 Skin 1.00 protein_coding synonymous_variant LOW 366T>C Cys122Cys
M0031593 FNNAPPJD_00010 7151 3 Skin 1.00 protein_coding synonymous_variant LOW 393A>T Ala131Ala
M0031594 FNNAPPJD_00010 7160 3 Skin 1.00 protein_coding synonymous_variant LOW 402G>T Thr134Thr
M0118434 FNNAPPJD_00006 3506 3 Oral 0.75 protein_coding synonymous_variant LOW 153G>A Gln51Gln
M0118435 FNNAPPJD_00007 3663 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -163G>A None
M0118436 FNNAPPJD_00007 4781 3 Oral 0.75 protein_coding missense_variant MODERATE 956C>T Ala319Val
M0118437 FNNAPPJD_00007 4839 3 Oral 0.75 protein_coding synonymous_variant LOW 1014G>A Ala338Ala
M0118438 FNNAPPJD_00007 4884 3 Oral 0.75 protein_coding synonymous_variant LOW 1059T>C Ile353Ile
M0118439 FNNAPPJD_00009 6531 3 Oral 0.75 protein_coding missense_variant MODERATE 89G>A Ser30Asn
M0118440 FNNAPPJD_00009 6533 3 Oral 0.75 protein_coding synonymous_variant LOW 87T>C Ala29Ala
M0118441 FNNAPPJD_00009 6535 3 Oral 0.75 protein_coding missense_variant MODERATE 85G>A Ala29Thr
M0118442 FNNAPPJD_00009 6538 3 Oral 0.75 protein_coding missense_variant MODERATE 82A>C Thr28Pro
M0118443 FNNAPPJD_00009 6574 3 Oral 0.75 protein_coding missense_variant MODERATE 46T>G Phe16Val
M0118444 FNNAPPJD_00009 6592 3 Oral 0.75 protein_coding missense_variant MODERATE 28A>G Thr10Ala
M0118445 FNNAPPJD_00008 6670 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -919G>A None
M0118446 FNNAPPJD_00010 6774 3 Oral 0.75 protein_coding missense_variant MODERATE 16C>A His6Asn
M0118447 FNNAPPJD_00010 6809 3 Oral 0.75 protein_coding synonymous_variant LOW 51G>A Pro17Pro
M0118448 FNNAPPJD_00010 6812 3 Oral 0.75 protein_coding synonymous_variant LOW 54G>A Thr18Thr
M0118449 FNNAPPJD_00010 6887 3 Oral 0.75 protein_coding synonymous_variant LOW 129T>C Ala43Ala
M0118450 FNNAPPJD_00010 6998 3 Oral 0.75 protein_coding synonymous_variant LOW 240T>C Gly80Gly
M0118451 FNNAPPJD_00010 7347 3 Oral 0.75 protein_coding missense_variant MODERATE 589A>G Ile197Val
M0118452 FNNAPPJD_00010 7352 3 Oral 0.75 protein_coding synonymous_variant LOW 594C>T Tyr198Tyr
M0118453 FNNAPPJD_00011 7884 3 Oral 0.75 protein_coding synonymous_variant LOW 87T>C Val29Val
M0118454 FNNAPPJD_00011 7920 3 Oral 0.75 protein_coding synonymous_variant LOW 123G>A Leu41Leu
M0118455 FNNAPPJD_00011 7924 3 Oral 0.75 protein_coding synonymous_variant LOW 127T>C Leu43Leu
M0118456 FNNAPPJD_00011 7963 3 Oral 0.75 protein_coding missense_variant MODERATE 166G>A Ala56Thr
M0118457 FNNAPPJD_00011 8121 3 Oral 0.75 protein_coding synonymous_variant LOW 324G>T Gly108Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term