Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2251
  Reference Plasmid   1111525849755863_bin.1__k141_75035
  Reference Plasmid Size   9845
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0031663 KGDOFKAF_00008 6988 3 Skin 0.60 protein_coding synonymous_variant LOW 984G>A Lys328Lys
M0031664 KGDOFKAF_00008 7003 3 Skin 0.60 protein_coding synonymous_variant LOW 999A>T Ile333Ile
M0031665 KGDOFKAF_00008 7034 3 Skin 0.60 protein_coding missense_variant MODERATE 1030G>A Asp344Asn
M0031666 KGDOFKAF_00008 7048 4 Skin 0.80 protein_coding synonymous_variant LOW 1044C>T Leu348Leu
M0031667 KGDOFKAF_00008 7219 5 Skin 1.00 protein_coding synonymous_variant LOW 1215A>G Val405Val
M0031668 KGDOFKAF_00009 7336 4 Skin 0.80 protein_coding synonymous_variant LOW 885A>C Gly295Gly
M0031669 KGDOFKAF_00009 7354 3 Skin 0.60 protein_coding synonymous_variant LOW 867T>C Asp289Asp
M0031670 KGDOFKAF_00009 7597 3 Skin 0.60 protein_coding synonymous_variant LOW 624A>G Leu208Leu
M0031671 KGDOFKAF_00009 7600 3 Skin 0.60 protein_coding synonymous_variant LOW 621G>A Arg207Arg
M0031672 KGDOFKAF_00009 7602 3 Skin 0.60 protein_coding synonymous_variant LOW 619A>C Arg207Arg
M0031673 KGDOFKAF_00009 7612 3 Skin 0.60 protein_coding synonymous_variant LOW 609C>A Ser203Ser
M0031674 KGDOFKAF_00009 7807 4 Skin 0.80 protein_coding synonymous_variant LOW 414A>G Lys138Lys
M0031675 KGDOFKAF_00009 7819 4 Skin 0.80 protein_coding synonymous_variant LOW 402A>G Thr134Thr
M0031676 KGDOFKAF_00009 7981 4 Skin 0.80 protein_coding synonymous_variant LOW 240G>T Thr80Thr
M0031677 KGDOFKAF_00010 8252 3 Skin 0.60 protein_coding synonymous_variant LOW 1561T>C Leu521Leu
M0031678 KGDOFKAF_00010 8367 3 Skin 0.60 protein_coding synonymous_variant LOW 1446A>G Ala482Ala
M0031679 KGDOFKAF_00008 6868 4 Skin 0.80 protein_coding synonymous_variant LOW 864C>T Tyr288Tyr
M0031680 KGDOFKAF_00009 7369 3 Skin 0.60 protein_coding synonymous_variant LOW 852C>T Pro284Pro
M0031681 KGDOFKAF_00009 7552 3 Skin 0.60 protein_coding synonymous_variant LOW 669G>A Gly223Gly
M0031682 KGDOFKAF_00009 7582 3 Skin 0.60 protein_coding synonymous_variant LOW 639T>C Thr213Thr
M0031683 KGDOFKAF_00009 7960 3 Skin 0.60 protein_coding missense_variant MODERATE 261C>G Ile87Met






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term