Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2262
  Reference Plasmid   1111525849758568_bin.24__k141_324213
  Reference Plasmid Size   16097
  Reference Plasmid GC Content   0.53
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0032012 DIFDFGNK_00001 128 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -297C>T None
M0032013 DIFDFGNK_00001 134 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -291A>G None
M0032014 DIFDFGNK_00001 137 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -288G>A None
M0032015 DIFDFGNK_00001 146 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -279C>T None
M0032016 DIFDFGNK_00001 152 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -273T>C None
M0032017 DIFDFGNK_00001 155 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -270G>A None
M0032018 DIFDFGNK_00001 158 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -267A>G None
M0032019 DIFDFGNK_00001 167 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -258G>C None
M0032020 DIFDFGNK_00001 173 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -252T>C None
M0032021 DIFDFGNK_00001 180 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -245A>G None
M0032022 DIFDFGNK_00001 197 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -228T>G None
M0032023 DIFDFGNK_00001 212 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -213T>C None
M0032024 DIFDFGNK_00001 304 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -121A>G None
M0032025 DIFDFGNK_00001 322 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -103A>G None
M0032026 DIFDFGNK_00001 329 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -96A>T None
M0032027 DIFDFGNK_00006 7902 4 Skin 0.29 protein_coding missense_variant MODERATE 125A>T His42Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
DIFDFGNK_00002 9.B.114.1.1 83.9 2.7e-113 1 236 0.9633 0.9874 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.114 The Vancomycin-sensitivity protein (SanA) Family
DIFDFGNK_00003 3.A.1.2.3 88.7 9.7e-162 1 336 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DIFDFGNK_00004 3.A.1.2.3 88.8 5.5e-262 4 502 0.9940 1.4851 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DIFDFGNK_00005 3.A.1.2.3 86.4 1.2e-161 1 330 1.0000 0.9851 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DIFDFGNK_00014 3.A.1.5.11 86 2.9e-106 2 223 0.9955 0.7327 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily