Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2271
  Reference Plasmid   1111525849758776_bin.22__k141_189023
  Reference Plasmid Size   6595
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0032355 GFDGGMEC_00001 294 8 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -22T>C None
M0032356 GFDGGMEC_00002 523 8 Skin 0.44 protein_coding synonymous_variant LOW 858T>C Arg286Arg
M0032357 GFDGGMEC_00002 628 6 Skin 0.33 protein_coding synonymous_variant LOW 753T>G Ala251Ala
M0032358 GFDGGMEC_00002 778 7 Skin 0.39 protein_coding synonymous_variant LOW 603A>G Glu201Glu
M0032359 GFDGGMEC_00002 786 6 Skin 0.33 protein_coding synonymous_variant LOW 595T>C Leu199Leu
M0032360 GFDGGMEC_00002 802 7 Skin 0.39 protein_coding synonymous_variant LOW 579T>C Gly193Gly
M0032361 GFDGGMEC_00002 1087 5 Skin 0.28 protein_coding synonymous_variant LOW 294T>C Asn98Asn
M0032362 GFDGGMEC_00002 1228 3 Skin 0.17 protein_coding synonymous_variant LOW 153C>T His51His
M0032363 GFDGGMEC_00002 1270 8 Skin 0.44 protein_coding synonymous_variant LOW 111T>C Leu37Leu
M0032364 GFDGGMEC_00002 1364 3 Skin 0.17 protein_coding missense_variant MODERATE 17A>C Glu6Ala
M0032365 GFDGGMEC_00002 1368 4 Skin 0.22 protein_coding missense_variant MODERATE 13C>T Pro5Ser
M0032366 GFDGGMEC_00001 1388 7 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -1116C>T None
M0032367 GFDGGMEC_00001 1392 7 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -1120A>C None
M0032368 GFDGGMEC_00001 1417 7 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -1145C>T None
M0032369 GFDGGMEC_00003 1498 6 Skin 0.33 protein_coding synonymous_variant LOW 1587C>G Gly529Gly
M0032370 GFDGGMEC_00003 1558 8 Skin 0.44 protein_coding synonymous_variant LOW 1527A>G Ala509Ala
M0032371 GFDGGMEC_00003 1632 8 Skin 0.44 protein_coding missense_variant MODERATE 1453A>G Thr485Ala
M0032372 GFDGGMEC_00003 1999 7 Skin 0.39 protein_coding synonymous_variant LOW 1086C>T Gly362Gly
M0032373 GFDGGMEC_00003 2614 8 Skin 0.44 protein_coding synonymous_variant LOW 471T>G Pro157Pro
M0032374 GFDGGMEC_00003 2626 8 Skin 0.44 protein_coding synonymous_variant LOW 459C>T Thr153Thr
M0032375 GFDGGMEC_00003 2629 5 Skin 0.28 protein_coding synonymous_variant LOW 456A>G Gly152Gly
M0032376 GFDGGMEC_00003 2845 7 Skin 0.39 protein_coding synonymous_variant LOW 240T>C Asn80Asn
M0032377 GFDGGMEC_00001 3203 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -2931C>G None
M0032378 GFDGGMEC_00001 3227 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -2955A>G None
M0032379 GFDGGMEC_00001 3662 7 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -3390A>G None
M0032380 GFDGGMEC_00005 3812 8 Skin 0.44 protein_coding synonymous_variant LOW 87G>C Ser29Ser
M0032381 GFDGGMEC_00005 4600 3 Skin 0.17 protein_coding missense_variant MODERATE 875A>G Lys292Arg
M0032382 GFDGGMEC_00005 4625 3 Skin 0.17 protein_coding synonymous_variant LOW 900C>T Gly300Gly
M0032383 GFDGGMEC_00005 4805 8 Skin 0.44 protein_coding synonymous_variant LOW 1080T>C Gly360Gly
M0032384 GFDGGMEC_00001 4897 7 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -4625G>A None
M0032385 GFDGGMEC_00006 5366 6 Skin 0.33 protein_coding synonymous_variant LOW 321T>C Asn107Asn
M0032386 GFDGGMEC_00006 5846 8 Skin 0.44 protein_coding missense_variant MODERATE 801G>C Glu267Asp
M0032387 GFDGGMEC_00006 5968 6 Skin 0.33 protein_coding missense_variant MODERATE 923G>A Gly308Asp
M0032388 GFDGGMEC_00006 6084 7 Skin 0.39 protein_coding missense_variant MODERATE 1039G>A Val347Ile
M0032389 GFDGGMEC_00006 6104 8 Skin 0.44 protein_coding synonymous_variant LOW 1059T>C Ser353Ser
M0032390 GFDGGMEC_00006 6193 8 Skin 0.44 protein_coding missense_variant MODERATE 1148G>A Arg383Gln
M0032391 GFDGGMEC_00002 476 6 Skin 0.33 protein_coding missense_variant MODERATE 905A>G His302Arg
M0032392 GFDGGMEC_00002 482 6 Skin 0.33 protein_coding missense_variant MODERATE 899C>A Ala300Glu
M0032393 GFDGGMEC_00002 751 5 Skin 0.28 protein_coding synonymous_variant LOW 630A>G Ala210Ala
M0032394 GFDGGMEC_00002 787 4 Skin 0.22 protein_coding synonymous_variant LOW 594C>G Gly198Gly
M0032395 GFDGGMEC_00002 943 5 Skin 0.28 protein_coding synonymous_variant LOW 438T>C Arg146Arg
M0032396 GFDGGMEC_00002 1004 4 Skin 0.22 protein_coding missense_variant MODERATE 377G>A Arg126Lys
M0032397 GFDGGMEC_00002 1145 6 Skin 0.33 protein_coding missense_variant MODERATE 236A>G Gln79Arg
M0032398 GFDGGMEC_00003 1620 3 Skin 0.17 protein_coding synonymous_variant LOW 1465C>T Leu489Leu
M0032399 GFDGGMEC_00003 1621 3 Skin 0.17 protein_coding synonymous_variant LOW 1464C>G Val488Val
M0032400 GFDGGMEC_00003 1783 3 Skin 0.17 protein_coding synonymous_variant LOW 1302C>T Phe434Phe
M0032401 GFDGGMEC_00003 1859 3 Skin 0.17 protein_coding missense_variant MODERATE 1226A>G Lys409Arg
M0032402 GFDGGMEC_00003 2542 4 Skin 0.22 protein_coding synonymous_variant LOW 543C>T His181His
M0032403 GFDGGMEC_00003 2630 3 Skin 0.17 protein_coding missense_variant MODERATE 455G>A Gly152Glu
M0032404 GFDGGMEC_00001 217 5 Skin 0.28 protein_coding missense_variant MODERATE 56C>A Pro19His
M0032405 GFDGGMEC_00005 3872 3 Skin 0.17 protein_coding synonymous_variant LOW 147G>A Pro49Pro
M0032406 GFDGGMEC_00005 4696 3 Skin 0.17 protein_coding missense_variant MODERATE 971A>G Lys324Arg
M0032407 GFDGGMEC_00005 4745 5 Skin 0.28 protein_coding synonymous_variant LOW 1020A>C Gly340Gly
M0032408 GFDGGMEC_00006 5858 3 Skin 0.17 protein_coding synonymous_variant LOW 813G>C Gly271Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term