Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2274
  Reference Plasmid   1111525849758776_bin.22__k141_68489
  Reference Plasmid Size   29451
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0032862 FMIKDLBM_00012 11391 3 Skin 0.18 protein_coding synonymous_variant LOW 1221C>G Leu407Leu
M0032863 FMIKDLBM_00012 11404 3 Skin 0.18 protein_coding missense_variant MODERATE 1208G>C Ser403Thr
M0032864 FMIKDLBM_00012 11780 3 Skin 0.18 protein_coding missense_variant MODERATE 832C>A Leu278Met
M0032865 FMIKDLBM_00012 11790 3 Skin 0.18 protein_coding synonymous_variant LOW 822G>C Gly274Gly
M0032866 FMIKDLBM_00012 11805 3 Skin 0.18 protein_coding synonymous_variant LOW 807T>C Ile269Ile
M0032867 FMIKDLBM_00012 11826 3 Skin 0.18 protein_coding synonymous_variant LOW 786A>G Thr262Thr
M0032868 FMIKDLBM_00012 11996 4 Skin 0.24 protein_coding synonymous_variant LOW 616T>C Leu206Leu
M0032869 FMIKDLBM_00012 12052 4 Skin 0.24 protein_coding missense_variant MODERATE 560T>C Ile187Thr
M0032870 FMIKDLBM_00012 12074 4 Skin 0.24 protein_coding missense_variant MODERATE 538G>A Gly180Ser
M0032871 FMIKDLBM_00012 12255 4 Skin 0.24 protein_coding synonymous_variant LOW 357T>G Leu119Leu
M0032872 FMIKDLBM_00012 12555 4 Skin 0.24 protein_coding synonymous_variant LOW 57T>C Ala19Ala
M0032873 FMIKDLBM_00012 12573 3 Skin 0.18 protein_coding synonymous_variant LOW 39C>T Ala13Ala
M0032874 FMIKDLBM_00012 12600 4 Skin 0.24 protein_coding synonymous_variant LOW 12G>C Leu4Leu
M0032875 FMIKDLBM_00013 12776 4 Skin 0.24 protein_coding missense_variant MODERATE 482T>C Met161Thr
M0032876 FMIKDLBM_00013 12811 4 Skin 0.24 protein_coding synonymous_variant LOW 447T>C Leu149Leu
M0032877 FMIKDLBM_00014 13699 6 Skin 0.35 protein_coding missense_variant MODERATE 361A>G Thr121Ala
M0032878 FMIKDLBM_00015 14444 6 Skin 0.35 protein_coding synonymous_variant LOW 927G>A Glu309Glu
M0032879 FMIKDLBM_00015 14497 6 Skin 0.35 protein_coding missense_variant MODERATE 874A>G Thr292Ala
M0032880 FMIKDLBM_00015 14498 6 Skin 0.35 protein_coding synonymous_variant LOW 873A>G Arg291Arg
M0032881 FMIKDLBM_00015 14501 6 Skin 0.35 protein_coding synonymous_variant LOW 870A>G Gly290Gly
M0032882 FMIKDLBM_00015 14502 6 Skin 0.35 protein_coding missense_variant MODERATE 869G>C Gly290Ala
M0032883 FMIKDLBM_00015 14504 6 Skin 0.35 protein_coding synonymous_variant LOW 867T>G Thr289Thr
M0032884 FMIKDLBM_00015 14505 6 Skin 0.35 protein_coding missense_variant MODERATE 866C>G Thr289Ser
M0032885 FMIKDLBM_00015 14506 6 Skin 0.35 protein_coding missense_variant MODERATE 865A>G Thr289Ala
M0032886 FMIKDLBM_00015 14553 6 Skin 0.35 protein_coding missense_variant MODERATE 818T>C Val273Ala
M0032887 FMIKDLBM_00015 14823 6 Skin 0.35 protein_coding missense_variant MODERATE 548G>A Arg183Gln
M0032888 FMIKDLBM_00015 15154 6 Skin 0.35 protein_coding synonymous_variant LOW 217T>C Leu73Leu
M0032889 FMIKDLBM_00015 15335 3 Skin 0.18 protein_coding synonymous_variant LOW 36G>A Ser12Ser
M0032890 FMIKDLBM_00012 15467 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -2856C>G None
M0032891 FMIKDLBM_00016 15602 6 Skin 0.35 protein_coding synonymous_variant LOW 537A>C Ala179Ala
M0032892 FMIKDLBM_00016 15713 5 Skin 0.29 protein_coding synonymous_variant LOW 426G>C Ala142Ala
M0032893 FMIKDLBM_00016 15965 4 Skin 0.24 protein_coding synonymous_variant LOW 174T>C Ala58Ala
M0032894 FMIKDLBM_00012 11736 3 Skin 0.18 protein_coding synonymous_variant LOW 876A>G Lys292Lys
M0032895 FMIKDLBM_00012 12366 3 Skin 0.18 protein_coding synonymous_variant LOW 246G>C Leu82Leu
M0032896 FMIKDLBM_00014 14026 5 Skin 0.29 protein_coding missense_variant MODERATE 688G>C Asp230His
M0032897 FMIKDLBM_00015 14375 4 Skin 0.24 protein_coding synonymous_variant LOW 996T>G Ala332Ala
M0032898 FMIKDLBM_00015 14495 3 Skin 0.18 protein_coding synonymous_variant LOW 876T>C Thr292Thr
M0032899 FMIKDLBM_00015 14698 3 Skin 0.18 protein_coding missense_variant MODERATE 673G>A Val225Met
M0032900 FMIKDLBM_00016 15476 4 Skin 0.24 protein_coding synonymous_variant LOW 663G>C Arg221Arg
M0032901 FMIKDLBM_00016 15692 3 Skin 0.18 protein_coding synonymous_variant LOW 447G>C Leu149Leu
M0032902 FMIKDLBM_00016 15773 4 Skin 0.24 protein_coding synonymous_variant LOW 366C>G Ala122Ala
M0032903 FMIKDLBM_00016 15803 3 Skin 0.18 protein_coding missense_variant MODERATE 336C>G Asp112Glu
M0032904 FMIKDLBM_00023 24304 3 Skin 0.18 protein_coding synonymous_variant LOW 780T>C Arg260Arg
M0032905 FMIKDLBM_00023 24378 3 Skin 0.18 protein_coding missense_variant MODERATE 854A>G Asp285Gly
M0032906 FMIKDLBM_00023 24379 3 Skin 0.18 protein_coding missense_variant MODERATE 855T>G Asp285Glu
M0032907 FMIKDLBM_00024 25215 5 Skin 0.29 protein_coding synonymous_variant LOW 741T>C Tyr247Tyr
M0032908 FMIKDLBM_00024 25340 3 Skin 0.18 protein_coding missense_variant MODERATE 866G>A Ser289Asn
M0032909 FMIKDLBM_00025 25558 5 Skin 0.29 protein_coding missense_variant MODERATE 14G>A Arg5Gln
M0032910 FMIKDLBM_00025 25637 5 Skin 0.29 protein_coding synonymous_variant LOW 93T>C Tyr31Tyr
M0032911 FMIKDLBM_00025 25682 5 Skin 0.29 protein_coding synonymous_variant LOW 138T>C Thr46Thr
M0032912 FMIKDLBM_00025 25763 5 Skin 0.29 protein_coding synonymous_variant LOW 219T>C Gly73Gly
M0032913 FMIKDLBM_00025 25772 5 Skin 0.29 protein_coding synonymous_variant LOW 228A>C Gly76Gly
M0032914 FMIKDLBM_00025 26220 5 Skin 0.29 protein_coding missense_variant MODERATE 676A>G Asn226Asp
M0032915 FMIKDLBM_00026 26961 5 Skin 0.29 protein_coding synonymous_variant LOW 282A>G Val94Val
M0032916 FMIKDLBM_00026 27234 5 Skin 0.29 protein_coding synonymous_variant LOW 555A>G Thr185Thr
M0032917 FMIKDLBM_00026 27261 3 Skin 0.18 protein_coding synonymous_variant LOW 582C>T Asp194Asp
M0032918 FMIKDLBM_00027 27723 5 Skin 0.29 protein_coding synonymous_variant LOW 138A>G Lys46Lys
M0032919 FMIKDLBM_00027 27917 5 Skin 0.29 protein_coding missense_variant MODERATE 332C>G Ala111Gly
M0032920 FMIKDLBM_00027 28021 4 Skin 0.24 protein_coding synonymous_variant LOW 436A>C Arg146Arg
M0032921 FMIKDLBM_00027 28023 4 Skin 0.24 protein_coding missense_variant MODERATE 438G>C Arg146Ser
M0032922 FMIKDLBM_00027 28026 4 Skin 0.24 protein_coding synonymous_variant LOW 441G>C Gly147Gly
M0032923 FMIKDLBM_00027 28032 3 Skin 0.18 protein_coding synonymous_variant LOW 447G>C Val149Val
M0032924 FMIKDLBM_00027 28035 3 Skin 0.18 protein_coding synonymous_variant LOW 450T>G Ala150Ala
M0032925 FMIKDLBM_00027 28230 5 Skin 0.29 protein_coding synonymous_variant LOW 645G>A Val215Val
M0032926 FMIKDLBM_00027 28245 5 Skin 0.29 protein_coding synonymous_variant LOW 660A>C Pro220Pro
M0032927 FMIKDLBM_00028 28784 4 Skin 0.24 protein_coding synonymous_variant LOW 504A>G Val168Val
M0032928 FMIKDLBM_00028 28827 4 Skin 0.24 protein_coding missense_variant MODERATE 547A>C Asn183His
M0032929 FMIKDLBM_00028 28828 4 Skin 0.24 protein_coding missense_variant MODERATE 548A>G Asn183Ser
M0032930 FMIKDLBM_00004 2777 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -808A>G None
M0032931 FMIKDLBM_00003 3283 3 Skin 0.18 protein_coding missense_variant MODERATE 235T>C Ser79Pro
M0032932 FMIKDLBM_00004 5379 3 Skin 0.18 protein_coding missense_variant MODERATE 1795C>T His599Tyr
M0032933 FMIKDLBM_00024 25263 3 Skin 0.18 protein_coding synonymous_variant LOW 789G>T Ser263Ser
M0032934 FMIKDLBM_00027 28070 3 Skin 0.18 protein_coding missense_variant MODERATE 485G>A Arg162Lys
M0032935 FMIKDLBM_00023 28959 3 Skin 0.18 protein_coding downstream_gene_variant MODIFIER *4490T>G None
M0032936 FMIKDLBM_00023 28960 3 Skin 0.18 protein_coding downstream_gene_variant MODIFIER *4491C>A None
M0032937 FMIKDLBM_00001 299 3 Skin 0.18 protein_coding missense_variant MODERATE 235A>G Thr79Ala
M0032938 FMIKDLBM_00002 432 3 Skin 0.18 protein_coding synonymous_variant LOW 15A>G Thr5Thr
M0032939 FMIKDLBM_00002 963 3 Skin 0.18 protein_coding synonymous_variant LOW 546C>G Thr182Thr
M0032940 FMIKDLBM_00002 1044 3 Skin 0.18 protein_coding synonymous_variant LOW 627A>G Leu209Leu
M0032941 FMIKDLBM_00002 1251 3 Skin 0.18 protein_coding synonymous_variant LOW 834T>C Ile278Ile
M0032942 FMIKDLBM_00002 1329 3 Skin 0.18 protein_coding synonymous_variant LOW 912G>C Ala304Ala
M0032943 FMIKDLBM_00002 1332 3 Skin 0.18 protein_coding synonymous_variant LOW 915G>C Val305Val
M0032944 FMIKDLBM_00002 1939 3 Skin 0.18 protein_coding missense_variant MODERATE 1522T>A Ser508Thr
M0032945 FMIKDLBM_00002 1940 3 Skin 0.18 protein_coding missense_variant MODERATE 1523C>G Ser508Trp
M0032946 FMIKDLBM_00002 1941 3 Skin 0.18 protein_coding synonymous_variant LOW 1524G>C Ser508Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term