Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2281
  Reference Plasmid   1111525849758951_bin.8__k141_196254
  Reference Plasmid Size   11616
  Reference Plasmid GC Content   0.54
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0033190 KJKBJOLP_00001 2512 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2260A>C None
M0033191 KJKBJOLP_00001 2535 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2283G>C None
M0033192 KJKBJOLP_00008 2883 3 Skin 0.43 protein_coding synonymous_variant LOW 678C>A Gly226Gly
M0033193 KJKBJOLP_00008 2940 3 Skin 0.43 protein_coding synonymous_variant LOW 621G>T Val207Val
M0033194 KJKBJOLP_00009 3758 5 Skin 0.71 protein_coding synonymous_variant LOW 2310T>G Val770Val
M0033195 KJKBJOLP_00009 3929 3 Skin 0.43 protein_coding synonymous_variant LOW 2139C>T Asp713Asp
M0033196 KJKBJOLP_00009 3944 3 Skin 0.43 protein_coding synonymous_variant LOW 2124A>C Ala708Ala
M0033197 KJKBJOLP_00009 5774 4 Skin 0.57 protein_coding synonymous_variant LOW 294A>G Lys98Lys
M0033198 KJKBJOLP_00009 5968 3 Skin 0.43 protein_coding missense_variant MODERATE 100A>G Asn34Asp
M0033199 KJKBJOLP_00010 6465 3 Skin 0.43 protein_coding synonymous_variant LOW 375C>T Asp125Asp
M0033200 KJKBJOLP_00010 6541 4 Skin 0.57 protein_coding missense_variant MODERATE 299G>A Arg100Lys
M0033201 KJKBJOLP_00012 7824 3 Skin 0.43 protein_coding missense_variant MODERATE 76G>A Val26Ile
M0033202 KJKBJOLP_00012 7848 3 Skin 0.43 protein_coding missense_variant MODERATE 52C>T Arg18Cys
M0033203 KJKBJOLP_00012 7855 3 Skin 0.43 protein_coding synonymous_variant LOW 45A>G Val15Val
M0033204 KJKBJOLP_00013 8088 5 Skin 0.71 protein_coding synonymous_variant LOW 351T>C Tyr117Tyr
M0033205 KJKBJOLP_00013 8157 5 Skin 0.71 protein_coding synonymous_variant LOW 282T>C Thr94Thr
M0033206 KJKBJOLP_00013 8163 5 Skin 0.71 protein_coding synonymous_variant LOW 276G>A Ala92Ala
M0033207 KJKBJOLP_00013 8348 5 Skin 0.71 protein_coding missense_variant MODERATE 91T>G Cys31Gly
M0033208 KJKBJOLP_00014 8999 4 Skin 0.57 protein_coding synonymous_variant LOW 1167A>G Glu389Glu
M0033209 KJKBJOLP_00009 4967 3 Skin 0.43 protein_coding synonymous_variant LOW 1101A>G Gly367Gly
M0033210 KJKBJOLP_00009 4997 3 Skin 0.43 protein_coding synonymous_variant LOW 1071C>T Asp357Asp
M0033211 KJKBJOLP_00011 7208 4 Skin 0.57 protein_coding synonymous_variant LOW 189T>C Ser63Ser
M0033212 KJKBJOLP_00011 7236 4 Skin 0.57 protein_coding missense_variant MODERATE 161A>G Asn54Ser
M0033213 KJKBJOLP_00012 7504 3 Skin 0.43 protein_coding synonymous_variant LOW 396A>G Thr132Thr
M0033214 KJKBJOLP_00012 7635 4 Skin 0.57 protein_coding missense_variant MODERATE 265A>G Ser89Gly
M0033215 KJKBJOLP_00013 8046 4 Skin 0.57 protein_coding synonymous_variant LOW 393A>G Thr131Thr
M0033216 KJKBJOLP_00011 6974 3 Skin 0.43 protein_coding synonymous_variant LOW 423G>T Val141Val
M0033217 KJKBJOLP_00011 6995 3 Skin 0.43 protein_coding synonymous_variant LOW 402C>T Asn134Asn
M0033218 KJKBJOLP_00011 7352 3 Skin 0.43 protein_coding synonymous_variant LOW 45T>C Ser15Ser
M0033219 KJKBJOLP_00011 7358 3 Skin 0.43 protein_coding synonymous_variant LOW 39A>G Leu13Leu
M0033220 KJKBJOLP_00001 2220 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1968G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term