Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2286
  Reference Plasmid   1111525849759006_bin.27__k141_301153
  Reference Plasmid Size   22012
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0033737 ABPDEGNK_00020 16989 3 Skin 0.27 protein_coding missense_variant MODERATE 170T>G Leu57Arg
M0033738 ABPDEGNK_00015 17168 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -4769G>T None
M0033739 ABPDEGNK_00021 17533 4 Skin 0.36 protein_coding synonymous_variant LOW 735A>G Glu245Glu
M0033740 ABPDEGNK_00021 17592 6 Skin 0.55 protein_coding missense_variant MODERATE 676G>A Ala226Thr
M0033741 ABPDEGNK_00021 17842 5 Skin 0.45 protein_coding synonymous_variant LOW 426C>A Ala142Ala
M0033742 ABPDEGNK_00021 17916 3 Skin 0.27 protein_coding synonymous_variant LOW 352C>T Leu118Leu
M0033743 ABPDEGNK_00021 18199 3 Skin 0.27 protein_coding synonymous_variant LOW 69A>G Pro23Pro
M0033744 ABPDEGNK_00022 19030 5 Skin 0.45 protein_coding missense_variant MODERATE 233T>C Leu78Pro
M0033745 ABPDEGNK_00022 19081 5 Skin 0.45 protein_coding missense_variant MODERATE 182C>T Ala61Val
M0033746 ABPDEGNK_00023 19436 3 Skin 0.27 protein_coding missense_variant MODERATE 595G>C Ala199Pro
M0033747 ABPDEGNK_00023 19482 5 Skin 0.45 protein_coding synonymous_variant LOW 549A>G Val183Val
M0033748 ABPDEGNK_00023 19490 5 Skin 0.45 protein_coding missense_variant MODERATE 541T>C Ser181Pro
M0033749 ABPDEGNK_00017 13409 6 Skin 0.55 protein_coding missense_variant MODERATE 989C>T Thr330Ile
M0033750 ABPDEGNK_00017 13411 4 Skin 0.36 protein_coding synonymous_variant LOW 987T>G Gly329Gly
M0033751 ABPDEGNK_00017 13536 5 Skin 0.45 protein_coding synonymous_variant LOW 862T>C Leu288Leu
M0033752 ABPDEGNK_00017 13800 4 Skin 0.36 protein_coding synonymous_variant LOW 598T>C Leu200Leu
M0033753 ABPDEGNK_00017 13894 4 Skin 0.36 protein_coding synonymous_variant LOW 504C>G Thr168Thr
M0033754 ABPDEGNK_00017 14131 5 Skin 0.45 protein_coding missense_variant MODERATE 267G>C Glu89Asp
M0033755 ABPDEGNK_00017 14228 6 Skin 0.55 protein_coding missense_variant MODERATE 170T>C Val57Ala
M0033756 ABPDEGNK_00017 14230 6 Skin 0.55 protein_coding synonymous_variant LOW 168G>A Glu56Glu
M0033757 ABPDEGNK_00017 14244 6 Skin 0.55 protein_coding missense_variant MODERATE 154A>G Arg52Gly
M0033758 ABPDEGNK_00018 14570 6 Skin 0.55 protein_coding synonymous_variant LOW 945A>G Val315Val
M0033759 ABPDEGNK_00018 14966 3 Skin 0.27 protein_coding synonymous_variant LOW 549C>T Ala183Ala
M0033760 ABPDEGNK_00018 14993 3 Skin 0.27 protein_coding synonymous_variant LOW 522C>T Asp174Asp
M0033761 ABPDEGNK_00019 16161 3 Skin 0.27 protein_coding synonymous_variant LOW 213G>A Gln71Gln
M0033762 ABPDEGNK_00019 16317 6 Skin 0.55 protein_coding synonymous_variant LOW 57C>T Ile19Ile
M0033763 ABPDEGNK_00020 16487 3 Skin 0.27 protein_coding synonymous_variant LOW 672G>A Pro224Pro
M0033764 ABPDEGNK_00021 17746 3 Skin 0.27 protein_coding synonymous_variant LOW 522A>G Glu174Glu
M0033765 ABPDEGNK_00024 20287 3 Skin 0.27 protein_coding missense_variant MODERATE 448A>G Ile150Val
M0033766 ABPDEGNK_00015 12139 3 Skin 0.27 protein_coding synonymous_variant LOW 261T>C Arg87Arg
M0033767 ABPDEGNK_00016 13103 4 Skin 0.36 protein_coding synonymous_variant LOW 237T>C Asp79Asp
M0033768 ABPDEGNK_00017 13809 3 Skin 0.27 protein_coding missense_variant MODERATE 589C>T His197Tyr
M0033769 ABPDEGNK_00022 18294 4 Skin 0.36 protein_coding synonymous_variant LOW 969C>T His323His
M0033770 ABPDEGNK_00022 18815 4 Skin 0.36 protein_coding missense_variant MODERATE 448A>G Ser150Gly
M0033771 ABPDEGNK_00022 18826 4 Skin 0.36 protein_coding missense_variant MODERATE 437C>A Ala146Glu
M0033772 ABPDEGNK_00013 10950 3 Skin 0.27 protein_coding synonymous_variant LOW 285C>G Ala95Ala
M0033773 ABPDEGNK_00013 11175 3 Skin 0.27 protein_coding synonymous_variant LOW 60A>G Gln20Gln
M0033774 ABPDEGNK_00016 12595 3 Skin 0.27 protein_coding missense_variant MODERATE 745T>C Ser249Pro
M0033775 ABPDEGNK_00016 13307 3 Skin 0.27 protein_coding synonymous_variant LOW 33A>G Ala11Ala
M0033776 ABPDEGNK_00019 15741 3 Skin 0.27 protein_coding synonymous_variant LOW 633G>A Val211Val
M0033777 ABPDEGNK_00019 16176 3 Skin 0.27 protein_coding synonymous_variant LOW 198C>T Ser66Ser
M0033778 ABPDEGNK_00020 16687 3 Skin 0.27 protein_coding missense_variant MODERATE 472C>G Gln158Glu
M0033779 ABPDEGNK_00021 17529 3 Skin 0.27 protein_coding missense_variant MODERATE 739G>A Val247Met






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
ABPDEGNK_00014 Tellurium (Te) 70.2 5.3e-74 1 191 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term