Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2312
  Reference Plasmid   1111525849766308_bin.16__k141_210154
  Reference Plasmid Size   12827
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0036951 DBIMAFBK_00013 11682 3 Skin 0.33 protein_coding synonymous_variant LOW 177C>T Cys59Cys
M0036952 DBIMAFBK_00009 8112 3 Skin 0.33 protein_coding synonymous_variant LOW 756A>G Arg252Arg
M0036953 DBIMAFBK_00009 8114 3 Skin 0.33 protein_coding missense_variant MODERATE 758C>G Thr253Ser
M0036954 DBIMAFBK_00010 9430 3 Skin 0.33 protein_coding synonymous_variant LOW 1107T>C Leu369Leu
M0036955 DBIMAFBK_00010 10078 4 Skin 0.44 protein_coding stop_lost&splice_region_variant HIGH 1755G>T Ter585Tyrext*?
M0036956 DBIMAFBK_00011 10131 4 Skin 0.44 protein_coding missense_variant MODERATE 29A>T Asp10Val
M0036957 DBIMAFBK_00011 10315 3 Skin 0.33 protein_coding synonymous_variant LOW 213C>G Ala71Ala
M0036958 DBIMAFBK_00011 10327 3 Skin 0.33 protein_coding synonymous_variant LOW 225C>T Asp75Asp
M0036959 DBIMAFBK_00012 10859 3 Skin 0.33 protein_coding synonymous_variant LOW 270T>C Asp90Asp
M0036960 DBIMAFBK_00012 10886 3 Skin 0.33 protein_coding synonymous_variant LOW 297C>G Ala99Ala
M0036961 DBIMAFBK_00012 10952 3 Skin 0.33 protein_coding missense_variant MODERATE 363C>G Asp121Glu
M0036962 DBIMAFBK_00001 49 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -27G>A None
M0036963 DBIMAFBK_00001 70 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -6G>A None
M0036964 DBIMAFBK_00001 368 5 Skin 0.56 protein_coding missense_variant MODERATE 293C>T Ala98Val
M0036965 DBIMAFBK_00004 1545 3 Skin 0.33 protein_coding synonymous_variant LOW 21G>C Gly7Gly
M0036966 DBIMAFBK_00004 1546 3 Skin 0.33 protein_coding missense_variant MODERATE 22T>G Phe8Val
M0036967 DBIMAFBK_00004 1683 3 Skin 0.33 protein_coding synonymous_variant LOW 159A>G Ala53Ala
M0036968 DBIMAFBK_00004 1783 4 Skin 0.44 protein_coding missense_variant MODERATE 259A>C Met87Leu
M0036969 DBIMAFBK_00004 1974 3 Skin 0.33 protein_coding synonymous_variant LOW 450A>C Ala150Ala
M0036970 DBIMAFBK_00004 1977 3 Skin 0.33 protein_coding synonymous_variant LOW 453C>G Val151Val
M0036971 DBIMAFBK_00004 2079 3 Skin 0.33 protein_coding synonymous_variant LOW 555T>C Ile185Ile
M0036972 DBIMAFBK_00004 2091 3 Skin 0.33 protein_coding synonymous_variant LOW 567T>C Tyr189Tyr
M0036973 DBIMAFBK_00004 2112 3 Skin 0.33 protein_coding synonymous_variant LOW 588C>T Ser196Ser
M0036974 DBIMAFBK_00004 2131 3 Skin 0.33 protein_coding missense_variant MODERATE 607G>A Ala203Thr
M0036975 DBIMAFBK_00004 3108 3 Skin 0.33 protein_coding synonymous_variant LOW 1584G>C Ala528Ala
M0036976 DBIMAFBK_00005 4618 3 Skin 0.33 protein_coding missense_variant MODERATE 1379G>T Arg460Leu
M0036977 DBIMAFBK_00005 4627 3 Skin 0.33 protein_coding missense_variant MODERATE 1388G>T Arg463Met
M0036978 DBIMAFBK_00005 4633 3 Skin 0.33 protein_coding missense_variant MODERATE 1394C>T Thr465Ile
M0036979 DBIMAFBK_00005 4648 3 Skin 0.33 protein_coding missense_variant MODERATE 1409C>T Thr470Ile
M0036980 DBIMAFBK_00005 4660 3 Skin 0.33 protein_coding missense_variant MODERATE 1421C>A Thr474Asn
M0036981 DBIMAFBK_00012 11312 3 Skin 0.33 protein_coding synonymous_variant LOW 723G>A Arg241Arg
M0036982 DBIMAFBK_00013 11565 3 Skin 0.33 protein_coding synonymous_variant LOW 60G>A Gly20Gly
M0036983 DBIMAFBK_00004 1772 3 Skin 0.33 protein_coding missense_variant MODERATE 248T>C Val83Ala
M0036984 DBIMAFBK_00004 1793 3 Skin 0.33 protein_coding missense_variant MODERATE 269C>G Ala90Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term