Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2308
  Reference Plasmid   1111525849766308_bin.1_new__k141_45863
  Reference Plasmid Size   39607
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0036994 PCEGNNDM_00007 10506 10 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -1858T>G None
M0036995 PCEGNNDM_00010 10165 3 Skin 0.04 protein_coding missense_variant MODERATE 33T>G Phe11Leu
M0036996 PCEGNNDM_00004 4521 8 Skin 0.09 protein_coding missense_variant MODERATE 3088A>G Asn1030Asp
M0036997 PCEGNNDM_00004 4589 9 Skin 0.11 protein_coding synonymous_variant LOW 3156G>A Thr1052Thr
M0036998 PCEGNNDM_00004 4385 10 Skin 0.12 protein_coding synonymous_variant LOW 2952A>T Leu984Leu
M0036999 PCEGNNDM_00004 4394 10 Skin 0.12 protein_coding synonymous_variant LOW 2961G>T Arg987Arg
M0037000 PCEGNNDM_00004 4404 10 Skin 0.12 protein_coding synonymous_variant LOW 2971T>C Leu991Leu
M0037001 PCEGNNDM_00004 4409 10 Skin 0.12 protein_coding synonymous_variant LOW 2976A>G Arg992Arg
M0037002 PCEGNNDM_00004 4419 10 Skin 0.12 protein_coding synonymous_variant LOW 2986C>T Leu996Leu
M0037003 PCEGNNDM_00004 2097 3 Skin 0.04 protein_coding missense_variant MODERATE 664G>A Val222Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
PCEGNNDM_00018 ATE66816.1|GH23 81.6 1.97e-118 8 230 0.9571 0.9485





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term