Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2316
  Reference Plasmid   1111525849766308_bin.2__k141_182239
  Reference Plasmid Size   21312
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0037103 BCOBNFCG_00009 7134 10 Skin 0.24 protein_coding synonymous_variant LOW 1767G>T Leu589Leu
M0037104 BCOBNFCG_00009 7137 10 Skin 0.24 protein_coding synonymous_variant LOW 1764A>G Gly588Gly
M0037105 BCOBNFCG_00014 13840 11 Skin 0.27 protein_coding synonymous_variant LOW 672A>C Pro224Pro
M0037106 BCOBNFCG_00010 14526 13 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -4996G>T None
M0037107 BCOBNFCG_00015 14812 14 Skin 0.34 protein_coding synonymous_variant LOW 198C>T Arg66Arg
M0037108 BCOBNFCG_00021 20981 5 Skin 0.12 protein_coding missense_variant MODERATE 423A>C Leu141Phe
M0037109 BCOBNFCG_00015 14836 4 Skin 0.10 protein_coding synonymous_variant LOW 222G>A Glu74Glu
M0037110 BCOBNFCG_00015 14845 4 Skin 0.10 protein_coding synonymous_variant LOW 231C>G Thr77Thr
M0037111 BCOBNFCG_00015 14848 4 Skin 0.10 protein_coding synonymous_variant LOW 234C>G Pro78Pro
M0037112 BCOBNFCG_00015 14863 4 Skin 0.10 protein_coding synonymous_variant LOW 249T>G Arg83Arg
M0037113 BCOBNFCG_00015 14884 5 Skin 0.12 protein_coding synonymous_variant LOW 270C>T Asn90Asn
M0037114 BCOBNFCG_00015 14911 3 Skin 0.07 protein_coding synonymous_variant LOW 297C>G Ala99Ala
M0037115 BCOBNFCG_00015 14914 3 Skin 0.07 protein_coding synonymous_variant LOW 300C>G Val100Val
M0037116 BCOBNFCG_00015 14917 3 Skin 0.07 protein_coding synonymous_variant LOW 303C>G Gly101Gly
M0037117 BCOBNFCG_00015 14941 3 Skin 0.07 protein_coding synonymous_variant LOW 327G>C Val109Val
M0037118 BCOBNFCG_00015 14962 3 Skin 0.07 protein_coding synonymous_variant LOW 348G>C Ala116Ala
M0037119 BCOBNFCG_00015 14965 3 Skin 0.07 protein_coding synonymous_variant LOW 351G>C Ser117Ser
M0037120 BCOBNFCG_00015 14971 3 Skin 0.07 protein_coding synonymous_variant LOW 357T>C His119His
M0037121 BCOBNFCG_00015 14978 3 Skin 0.07 protein_coding missense_variant MODERATE 364A>T Ser122Cys
M0037122 BCOBNFCG_00015 14979 3 Skin 0.07 protein_coding missense_variant MODERATE 365G>C Ser122Thr
M0037123 BCOBNFCG_00015 14980 3 Skin 0.07 protein_coding missense_variant MODERATE 366C>G Ser122Arg
M0037124 BCOBNFCG_00015 14983 3 Skin 0.07 protein_coding synonymous_variant LOW 369T>C Ala123Ala
M0037125 BCOBNFCG_00015 14989 3 Skin 0.07 protein_coding synonymous_variant LOW 375T>A Ala125Ala
M0037126 BCOBNFCG_00015 14990 3 Skin 0.07 protein_coding synonymous_variant LOW 376C>T Leu126Leu
M0037127 BCOBNFCG_00009 7293 3 Skin 0.07 protein_coding synonymous_variant LOW 1608G>C Ser536Ser
M0037128 BCOBNFCG_00009 7296 3 Skin 0.07 protein_coding synonymous_variant LOW 1605T>G Leu535Leu
M0037129 BCOBNFCG_00009 7299 3 Skin 0.07 protein_coding synonymous_variant LOW 1602T>C Asn534Asn
M0037130 BCOBNFCG_00009 8109 3 Skin 0.07 protein_coding synonymous_variant LOW 792G>A Glu264Glu
M0037131 BCOBNFCG_00009 8112 3 Skin 0.07 protein_coding synonymous_variant LOW 789A>G Glu263Glu
M0037132 BCOBNFCG_00017 18222 3 Skin 0.07 protein_coding synonymous_variant LOW 1524T>G Val508Val
M0037133 BCOBNFCG_00017 18237 3 Skin 0.07 protein_coding synonymous_variant LOW 1539A>G Glu513Glu
M0037134 BCOBNFCG_00017 18239 3 Skin 0.07 protein_coding missense_variant MODERATE 1541G>A Arg514Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term