Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2319
  Reference Plasmid   1111525849766308_bin.2__k141_31519
  Reference Plasmid Size   8551
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0037150 MCFMAJMK_00003 5208 3 Skin 0.21 protein_coding synonymous_variant LOW 484T>C Leu162Leu
M0037151 MCFMAJMK_00003 5209 3 Skin 0.21 protein_coding synonymous_variant LOW 483C>T Asn161Asn
M0037152 MCFMAJMK_00004 6268 3 Skin 0.21 protein_coding synonymous_variant LOW 462G>C Leu154Leu
M0037153 MCFMAJMK_00004 6274 3 Skin 0.21 protein_coding synonymous_variant LOW 456G>A Glu152Glu
M0037154 MCFMAJMK_00004 6276 3 Skin 0.21 protein_coding missense_variant MODERATE 454G>C Glu152Gln
M0037155 MCFMAJMK_00004 6289 3 Skin 0.21 protein_coding synonymous_variant LOW 441G>C Thr147Thr
M0037156 MCFMAJMK_00004 6313 3 Skin 0.21 protein_coding synonymous_variant LOW 417C>G Leu139Leu
M0037157 MCFMAJMK_00004 6334 3 Skin 0.21 protein_coding synonymous_variant LOW 396C>T Ser132Ser
M0037158 MCFMAJMK_00004 6352 3 Skin 0.21 protein_coding synonymous_variant LOW 378C>G Arg126Arg
M0037159 MCFMAJMK_00003 5263 3 Skin 0.21 protein_coding synonymous_variant LOW 429C>T Tyr143Tyr
M0037160 MCFMAJMK_00005 7766 3 Skin 0.21 protein_coding synonymous_variant LOW 489G>A Ala163Ala
M0037161 MCFMAJMK_00005 7769 3 Skin 0.21 protein_coding synonymous_variant LOW 486C>G Ala162Ala
M0037162 MCFMAJMK_00005 7775 3 Skin 0.21 protein_coding synonymous_variant LOW 480A>G Glu160Glu
M0037163 MCFMAJMK_00005 7778 3 Skin 0.21 protein_coding synonymous_variant LOW 477G>C Leu159Leu
M0037164 MCFMAJMK_00005 7790 3 Skin 0.21 protein_coding synonymous_variant LOW 465T>C Gly155Gly
M0037165 MCFMAJMK_00005 7817 3 Skin 0.21 protein_coding synonymous_variant LOW 438C>A Thr146Thr
M0037166 MCFMAJMK_00005 7859 3 Skin 0.21 protein_coding synonymous_variant LOW 396C>T Thr132Thr
M0037167 MCFMAJMK_00005 7874 3 Skin 0.21 protein_coding synonymous_variant LOW 381G>C Val127Val
M0037168 MCFMAJMK_00005 7877 3 Skin 0.21 protein_coding synonymous_variant LOW 378C>T Asn126Asn
M0037169 MCFMAJMK_00005 7904 3 Skin 0.21 protein_coding synonymous_variant LOW 351C>T Leu117Leu
M0037170 MCFMAJMK_00005 7910 3 Skin 0.21 protein_coding synonymous_variant LOW 345C>G Arg115Arg
M0037171 MCFMAJMK_00005 7916 3 Skin 0.21 protein_coding synonymous_variant LOW 339C>G Thr113Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term