Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2331
  Reference Plasmid   1111525849766731_bin.9__k141_314553
  Reference Plasmid Size   14797
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0118690 MOCPCAMD_00004 4904 10 Oral 0.91 protein_coding missense_variant MODERATE 757A>G Lys253Glu
M0118691 MOCPCAMD_00004 5359 10 Oral 0.91 protein_coding synonymous_variant LOW 1212C>T Ser404Ser
M0118692 MOCPCAMD_00004 5361 10 Oral 0.91 protein_coding missense_variant MODERATE 1214A>G Asn405Ser
M0118693 MOCPCAMD_00004 5374 10 Oral 0.91 protein_coding synonymous_variant LOW 1227T>C Gly409Gly
M0118694 MOCPCAMD_00004 5384 10 Oral 0.91 protein_coding missense_variant MODERATE 1237G>C Ala413Pro
M0118695 MOCPCAMD_00004 5408 10 Oral 0.91 protein_coding missense_variant MODERATE 1261G>A Glu421Lys
M0118696 MOCPCAMD_00004 5444 10 Oral 0.91 protein_coding missense_variant MODERATE 1297T>G Ser433Ala
M0118697 MOCPCAMD_00004 5467 10 Oral 0.91 protein_coding synonymous_variant LOW 1320G>A Val440Val
M0118698 MOCPCAMD_00004 5510 10 Oral 0.91 protein_coding missense_variant MODERATE 1363A>G Lys455Glu
M0118699 MOCPCAMD_00004 5519 9 Oral 0.82 protein_coding missense_variant MODERATE 1372A>T Thr458Ser
M0118700 MOCPCAMD_00004 5522 10 Oral 0.91 protein_coding missense_variant MODERATE 1375A>G Ser459Gly
M0118701 MOCPCAMD_00002 5583 10 Oral 0.91 protein_coding upstream_gene_variant MODIFIER -4761A>G None
M0118702 MOCPCAMD_00005 5595 10 Oral 0.91 protein_coding missense_variant MODERATE 5A>G Lys2Arg
M0118703 MOCPCAMD_00005 5602 10 Oral 0.91 protein_coding missense_variant MODERATE 12A>T Leu4Phe
M0118704 MOCPCAMD_00005 5605 10 Oral 0.91 protein_coding missense_variant MODERATE 15T>A Phe5Leu
M0118705 MOCPCAMD_00005 5615 10 Oral 0.91 protein_coding missense_variant MODERATE 25G>A Val9Ile
M0118706 MOCPCAMD_00005 5635 9 Oral 0.82 protein_coding synonymous_variant LOW 45T>C Ile15Ile
M0118707 MOCPCAMD_00005 5715 10 Oral 0.91 protein_coding missense_variant MODERATE 125C>T Ser42Leu
M0118708 MOCPCAMD_00005 5756 10 Oral 0.91 protein_coding missense_variant MODERATE 166A>G Thr56Ala
M0118709 MOCPCAMD_00005 5812 10 Oral 0.91 protein_coding synonymous_variant LOW 222A>G Pro74Pro
M0118710 MOCPCAMD_00005 5817 10 Oral 0.91 protein_coding missense_variant MODERATE 227C>A Thr76Lys
M0118711 MOCPCAMD_00005 5851 9 Oral 0.82 protein_coding synonymous_variant LOW 261C>T Asn87Asn
M0118712 MOCPCAMD_00005 5858 10 Oral 0.91 protein_coding missense_variant MODERATE 268G>C Val90Leu
M0118713 MOCPCAMD_00005 5883 10 Oral 0.91 protein_coding missense_variant MODERATE 293G>A Gly98Asp
M0118714 MOCPCAMD_00005 5909 10 Oral 0.91 protein_coding missense_variant MODERATE 319G>A Asp107Asn
M0118715 MOCPCAMD_00005 5929 10 Oral 0.91 protein_coding missense_variant MODERATE 339A>T Lys113Asn
M0118716 MOCPCAMD_00005 5977 10 Oral 0.91 protein_coding synonymous_variant LOW 387T>C His129His
M0118717 MOCPCAMD_00005 6005 9 Oral 0.82 protein_coding missense_variant MODERATE 415C>A Gln139Lys
M0118718 MOCPCAMD_00005 6010 9 Oral 0.82 protein_coding synonymous_variant LOW 420T>C Phe140Phe
M0118719 MOCPCAMD_00005 6012 9 Oral 0.82 protein_coding missense_variant MODERATE 422T>C Val141Ala
M0118720 MOCPCAMD_00005 6019 9 Oral 0.82 protein_coding synonymous_variant LOW 429C>T Val143Val
M0118721 MOCPCAMD_00005 6041 9 Oral 0.82 protein_coding missense_variant MODERATE 451G>A Asp151Asn
M0118722 MOCPCAMD_00005 6053 9 Oral 0.82 protein_coding stop_gained HIGH 463C>T Gln155*
M0118723 MOCPCAMD_00006 6066 9 Oral 0.82 protein_coding upstream_gene_variant MODIFIER -41G>A None
M0118724 MOCPCAMD_00006 6070 9 Oral 0.82 protein_coding upstream_gene_variant MODIFIER -37C>T None
M0118725 MOCPCAMD_00006 6200 8 Oral 0.73 protein_coding missense_variant MODERATE 94G>A Asp32Asn
M0118726 MOCPCAMD_00006 6206 8 Oral 0.73 protein_coding synonymous_variant LOW 100T>C Leu34Leu
M0118727 MOCPCAMD_00006 6300 9 Oral 0.82 protein_coding missense_variant MODERATE 194A>G Asn65Ser
M0118728 MOCPCAMD_00006 6327 9 Oral 0.82 protein_coding missense_variant MODERATE 221C>T Thr74Met
M0118729 MOCPCAMD_00006 6451 9 Oral 0.82 protein_coding synonymous_variant LOW 345G>A Lys115Lys
M0118730 MOCPCAMD_00006 6589 9 Oral 0.82 protein_coding synonymous_variant LOW 483A>G Val161Val
M0118731 MOCPCAMD_00006 6607 9 Oral 0.82 protein_coding synonymous_variant LOW 501G>A Leu167Leu
M0118732 MOCPCAMD_00007 7591 8 Oral 0.73 protein_coding synonymous_variant LOW 810C>T Asn270Asn
M0118733 MOCPCAMD_00007 7675 8 Oral 0.73 protein_coding synonymous_variant LOW 894T>C Ser298Ser
M0118734 MOCPCAMD_00007 7694 8 Oral 0.73 protein_coding missense_variant MODERATE 913C>A Leu305Met
M0118735 MOCPCAMD_00007 7774 8 Oral 0.73 protein_coding synonymous_variant LOW 993C>T Gly331Gly
M0118736 MOCPCAMD_00003 3006 4 Oral 0.36 protein_coding synonymous_variant LOW 1428C>T Leu476Leu
M0118737 MOCPCAMD_00003 3931 7 Oral 0.64 protein_coding missense_variant MODERATE 2353C>T Leu785Phe
M0118738 MOCPCAMD_00003 3978 7 Oral 0.64 protein_coding synonymous_variant LOW 2400G>A Pro800Pro
M0118739 MOCPCAMD_00003 3988 7 Oral 0.64 protein_coding missense_variant MODERATE 2410A>G Ser804Gly
M0118740 MOCPCAMD_00009 10445 4 Oral 0.36 protein_coding synonymous_variant LOW 339C>T Tyr113Tyr
M0118741 MOCPCAMD_00012 12600 9 Oral 0.82 protein_coding upstream_gene_variant MODIFIER -120A>T None
M0118742 MOCPCAMD_00002 1209 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -387T>G None
M0118743 MOCPCAMD_00002 1212 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -390T>A None
M0118744 MOCPCAMD_00002 1236 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -414A>G None
M0118745 MOCPCAMD_00002 1242 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -420C>G None
M0118746 MOCPCAMD_00002 1245 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -423C>A None
M0118747 MOCPCAMD_00002 1247 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -425C>A None
M0118748 MOCPCAMD_00002 1272 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -450C>T None
M0118749 MOCPCAMD_00013 13800 3 Oral 0.27 protein_coding synonymous_variant LOW 12A>G Gln4Gln
M0118750 MOCPCAMD_00013 13806 3 Oral 0.27 protein_coding synonymous_variant LOW 6G>A Lys2Lys
M0118751 MOCPCAMD_00013 13993 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -182C>T None
M0118752 MOCPCAMD_00013 14002 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -191C>T None
M0118753 MOCPCAMD_00014 14058 3 Oral 0.27 protein_coding synonymous_variant LOW 423T>G Leu141Leu
M0118754 MOCPCAMD_00014 14085 3 Oral 0.27 protein_coding synonymous_variant LOW 396T>C Ser132Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term