Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2332
  Reference Plasmid   1111525849766731_bin.9__k141_453319
  Reference Plasmid Size   9243
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0118755 HHBFKECL_00002 636 3 Oral 0.75 protein_coding missense_variant MODERATE 215C>T Ala72Val
M0118756 HHBFKECL_00002 646 3 Oral 0.75 protein_coding synonymous_variant LOW 225G>A Gly75Gly
M0118757 HHBFKECL_00002 657 3 Oral 0.75 protein_coding missense_variant MODERATE 236G>A Cys79Tyr
M0118758 HHBFKECL_00003 807 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -129A>T None
M0118759 HHBFKECL_00003 962 3 Oral 0.75 protein_coding synonymous_variant LOW 27C>T Phe9Phe
M0118760 HHBFKECL_00003 1112 3 Oral 0.75 protein_coding synonymous_variant LOW 177G>A Ala59Ala
M0118761 HHBFKECL_00003 1367 3 Oral 0.75 protein_coding synonymous_variant LOW 432C>T Asp144Asp
M0118762 HHBFKECL_00003 1401 3 Oral 0.75 protein_coding synonymous_variant LOW 466C>T Leu156Leu
M0118763 HHBFKECL_00003 1490 3 Oral 0.75 protein_coding synonymous_variant LOW 555T>C Cys185Cys
M0118764 HHBFKECL_00003 1493 3 Oral 0.75 protein_coding synonymous_variant LOW 558T>C Phe186Phe
M0118765 HHBFKECL_00003 1772 3 Oral 0.75 protein_coding synonymous_variant LOW 837T>C Asp279Asp
M0118766 HHBFKECL_00005 2477 3 Oral 0.75 protein_coding synonymous_variant LOW 28T>C Leu10Leu
M0118767 HHBFKECL_00005 2574 3 Oral 0.75 protein_coding missense_variant MODERATE 125C>T Ala42Val
M0118768 HHBFKECL_00005 2615 3 Oral 0.75 protein_coding missense_variant MODERATE 166A>C Met56Leu
M0118769 HHBFKECL_00005 2732 3 Oral 0.75 protein_coding missense_variant MODERATE 283T>G Ser95Ala
M0118770 HHBFKECL_00005 2815 3 Oral 0.75 protein_coding synonymous_variant LOW 366A>G Thr122Thr
M0118771 HHBFKECL_00005 2827 3 Oral 0.75 protein_coding synonymous_variant LOW 378T>C Phe126Phe
M0118772 HHBFKECL_00005 2857 3 Oral 0.75 protein_coding synonymous_variant LOW 408C>T Tyr136Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term