Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2335
  Reference Plasmid   1111525849767265_bin.19__k141_236768
  Reference Plasmid Size   9537
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0037685 MJDMEGDG_00001 153 6 Skin 0.35 protein_coding synonymous_variant LOW 69A>C Thr23Thr
M0037686 MJDMEGDG_00001 161 10 Skin 0.59 protein_coding missense_variant MODERATE 77A>G His26Arg
M0037687 MJDMEGDG_00001 180 6 Skin 0.35 protein_coding synonymous_variant LOW 96T>C Thr32Thr
M0037688 MJDMEGDG_00001 216 8 Skin 0.47 protein_coding synonymous_variant LOW 132G>C Gly44Gly
M0037689 MJDMEGDG_00001 234 8 Skin 0.47 protein_coding synonymous_variant LOW 150T>C Gly50Gly
M0037690 MJDMEGDG_00002 629 12 Skin 0.71 protein_coding synonymous_variant LOW 51C>T Asp17Asp
M0037691 MJDMEGDG_00002 1051 11 Skin 0.65 protein_coding missense_variant MODERATE 473A>G Gln158Arg
M0037692 MJDMEGDG_00002 1072 11 Skin 0.65 protein_coding missense_variant MODERATE 494C>T Thr165Ile
M0037693 MJDMEGDG_00002 1232 12 Skin 0.71 protein_coding synonymous_variant LOW 654G>C Ala218Ala
M0037694 MJDMEGDG_00002 1233 12 Skin 0.71 protein_coding missense_variant MODERATE 655A>G Ile219Val
M0037695 MJDMEGDG_00002 1239 12 Skin 0.71 protein_coding missense_variant MODERATE 661A>G Lys221Glu
M0037696 MJDMEGDG_00002 1276 14 Skin 0.82 protein_coding missense_variant MODERATE 698G>A Gly233Glu
M0037697 MJDMEGDG_00002 1279 11 Skin 0.65 protein_coding missense_variant MODERATE 701T>C Val234Ala
M0037698 MJDMEGDG_00002 1283 11 Skin 0.65 protein_coding synonymous_variant LOW 705G>A Glu235Glu
M0037699 MJDMEGDG_00002 1285 11 Skin 0.65 protein_coding missense_variant MODERATE 707G>A Arg236Gln
M0037700 MJDMEGDG_00002 1291 11 Skin 0.65 protein_coding missense_variant MODERATE 713A>T Gln238Leu
M0037701 MJDMEGDG_00002 1292 11 Skin 0.65 protein_coding missense_variant MODERATE 714G>T Gln238His
M0037702 MJDMEGDG_00003 1555 5 Skin 0.29 protein_coding missense_variant MODERATE 118G>A Ala40Thr
M0037703 MJDMEGDG_00003 1571 5 Skin 0.29 protein_coding missense_variant MODERATE 134G>A Arg45His
M0037704 MJDMEGDG_00003 1851 14 Skin 0.82 protein_coding synonymous_variant LOW 414A>G Leu138Leu
M0037705 MJDMEGDG_00002 1178 9 Skin 0.53 protein_coding synonymous_variant LOW 600C>A Ile200Ile
M0037706 MJDMEGDG_00003 1464 8 Skin 0.47 protein_coding synonymous_variant LOW 27T>C Asp9Asp
M0037707 MJDMEGDG_00003 1488 9 Skin 0.53 protein_coding synonymous_variant LOW 51T>C Asp17Asp
M0037708 MJDMEGDG_00005 4144 3 Skin 0.18 protein_coding synonymous_variant LOW 408G>C Val136Val
M0037709 MJDMEGDG_00005 4378 3 Skin 0.18 protein_coding synonymous_variant LOW 642G>A Arg214Arg
M0037710 MJDMEGDG_00002 1334 3 Skin 0.18 protein_coding synonymous_variant LOW 756C>T Ile252Ile
M0037711 MJDMEGDG_00002 1353 3 Skin 0.18 protein_coding missense_variant MODERATE 775G>A Ala259Thr
M0037712 MJDMEGDG_00003 1740 3 Skin 0.18 protein_coding synonymous_variant LOW 303C>T Leu101Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
MJDMEGDG_00003 VEF17740.1|CBM50 96 2.82e-235 1 349 0.8389 0.8369





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term