Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2342
  Reference Plasmid   1111525849767380_bin.20__k141_89241
  Reference Plasmid Size   17431
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0037906 JFBMIOKP_00001 541 5 Skin 0.45 protein_coding synonymous_variant LOW 129T>C Ala43Ala
M0037907 JFBMIOKP_00001 547 5 Skin 0.45 protein_coding synonymous_variant LOW 123A>G Ala41Ala
M0037908 JFBMIOKP_00001 553 5 Skin 0.45 protein_coding synonymous_variant LOW 117A>G Pro39Pro
M0037909 JFBMIOKP_00001 592 5 Skin 0.45 protein_coding synonymous_variant LOW 78G>T Ala26Ala
M0037910 JFBMIOKP_00001 625 5 Skin 0.45 protein_coding synonymous_variant LOW 45C>T Arg15Arg
M0037911 JFBMIOKP_00001 649 5 Skin 0.45 protein_coding synonymous_variant LOW 21C>T Pro7Pro
M0037912 JFBMIOKP_00001 651 5 Skin 0.45 protein_coding missense_variant MODERATE 19C>A Pro7Thr
M0037913 JFBMIOKP_00001 655 5 Skin 0.45 protein_coding synonymous_variant LOW 15A>G Gln5Gln
M0037914 JFBMIOKP_00001 658 5 Skin 0.45 protein_coding synonymous_variant LOW 12T>C Asp4Asp
M0037915 JFBMIOKP_00002 707 5 Skin 0.45 protein_coding synonymous_variant LOW 388T>C Leu130Leu
M0037916 JFBMIOKP_00002 728 5 Skin 0.45 protein_coding missense_variant MODERATE 367A>G Ile123Val
M0037917 JFBMIOKP_00002 738 5 Skin 0.45 protein_coding synonymous_variant LOW 357C>T Tyr119Tyr
M0037918 JFBMIOKP_00002 744 5 Skin 0.45 protein_coding synonymous_variant LOW 351C>G Ala117Ala
M0037919 JFBMIOKP_00002 762 5 Skin 0.45 protein_coding synonymous_variant LOW 333C>G Ala111Ala
M0037920 JFBMIOKP_00002 768 5 Skin 0.45 protein_coding synonymous_variant LOW 327C>T Val109Val
M0037921 JFBMIOKP_00002 774 3 Skin 0.27 protein_coding synonymous_variant LOW 321C>T Ser107Ser
M0037922 JFBMIOKP_00002 775 3 Skin 0.27 protein_coding missense_variant MODERATE 320G>T Ser107Ile
M0037923 JFBMIOKP_00002 789 5 Skin 0.45 protein_coding synonymous_variant LOW 306T>C Phe102Phe
M0037924 JFBMIOKP_00002 792 5 Skin 0.45 protein_coding synonymous_variant LOW 303C>G Ala101Ala
M0037925 JFBMIOKP_00002 798 5 Skin 0.45 protein_coding synonymous_variant LOW 297A>C Arg99Arg
M0037926 JFBMIOKP_00002 801 5 Skin 0.45 protein_coding synonymous_variant LOW 294C>T Ser98Ser
M0037927 JFBMIOKP_00002 809 5 Skin 0.45 protein_coding missense_variant MODERATE 286G>A Val96Ile
M0037928 JFBMIOKP_00002 813 5 Skin 0.45 protein_coding synonymous_variant LOW 282T>C Phe94Phe
M0037929 JFBMIOKP_00002 882 5 Skin 0.45 protein_coding synonymous_variant LOW 213G>T Ser71Ser
M0037930 JFBMIOKP_00002 968 5 Skin 0.45 protein_coding synonymous_variant LOW 127C>T Leu43Leu
M0037931 JFBMIOKP_00002 1065 5 Skin 0.45 protein_coding synonymous_variant LOW 30A>G Gly10Gly
M0037932 JFBMIOKP_00001 1103 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -434G>A None
M0037933 JFBMIOKP_00003 1170 5 Skin 0.45 protein_coding synonymous_variant LOW 612T>C His204His
M0037934 JFBMIOKP_00003 1196 5 Skin 0.45 protein_coding missense_variant MODERATE 586G>A Ala196Thr
M0037935 JFBMIOKP_00003 1206 5 Skin 0.45 protein_coding synonymous_variant LOW 576T>C Pro192Pro
M0037936 JFBMIOKP_00003 1302 6 Skin 0.55 protein_coding synonymous_variant LOW 480C>G Ala160Ala
M0037937 JFBMIOKP_00003 1350 6 Skin 0.55 protein_coding synonymous_variant LOW 432C>T Arg144Arg
M0037938 JFBMIOKP_00003 1356 5 Skin 0.45 protein_coding missense_variant MODERATE 426C>G Asp142Glu
M0037939 JFBMIOKP_00003 1389 5 Skin 0.45 protein_coding synonymous_variant LOW 393T>C Gly131Gly
M0037940 JFBMIOKP_00003 1392 5 Skin 0.45 protein_coding synonymous_variant LOW 390C>G Val130Val
M0037941 JFBMIOKP_00003 1398 5 Skin 0.45 protein_coding synonymous_variant LOW 384A>G Glu128Glu
M0037942 JFBMIOKP_00003 1407 6 Skin 0.55 protein_coding synonymous_variant LOW 375G>C Gly125Gly
M0037943 JFBMIOKP_00003 1428 4 Skin 0.36 protein_coding synonymous_variant LOW 354C>G Leu118Leu
M0037944 JFBMIOKP_00003 1448 4 Skin 0.36 protein_coding synonymous_variant LOW 334C>A Arg112Arg
M0037945 JFBMIOKP_00003 1476 4 Skin 0.36 protein_coding synonymous_variant LOW 306G>C Ser102Ser
M0037946 JFBMIOKP_00003 1488 5 Skin 0.45 protein_coding synonymous_variant LOW 294T>A Ile98Ile
M0037947 JFBMIOKP_00003 1491 4 Skin 0.36 protein_coding synonymous_variant LOW 291T>C Tyr97Tyr
M0037948 JFBMIOKP_00003 1494 4 Skin 0.36 protein_coding synonymous_variant LOW 288G>C Leu96Leu
M0037949 JFBMIOKP_00003 1497 4 Skin 0.36 protein_coding synonymous_variant LOW 285C>G Thr95Thr
M0037950 JFBMIOKP_00003 1503 4 Skin 0.36 protein_coding synonymous_variant LOW 279C>T Asp93Asp
M0037951 JFBMIOKP_00003 1518 5 Skin 0.45 protein_coding synonymous_variant LOW 264C>G Gly88Gly
M0037952 JFBMIOKP_00003 1560 5 Skin 0.45 protein_coding synonymous_variant LOW 222T>C Asp74Asp
M0037953 JFBMIOKP_00001 1952 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -1283T>G None
M0037954 JFBMIOKP_00004 2036 3 Skin 0.27 protein_coding synonymous_variant LOW 81G>T Ser27Ser
M0037955 JFBMIOKP_00004 2078 7 Skin 0.64 protein_coding missense_variant MODERATE 123G>C Leu41Phe
M0037956 JFBMIOKP_00005 2642 7 Skin 0.64 protein_coding synonymous_variant LOW 63T>C Ala21Ala
M0037957 JFBMIOKP_00002 840 4 Skin 0.36 protein_coding synonymous_variant LOW 255G>A Leu85Leu
M0037958 JFBMIOKP_00004 2309 3 Skin 0.27 protein_coding synonymous_variant LOW 354C>G Val118Val
M0037959 JFBMIOKP_00005 3062 3 Skin 0.27 protein_coding synonymous_variant LOW 483C>G Ala161Ala
M0037960 JFBMIOKP_00006 4202 3 Skin 0.27 protein_coding synonymous_variant LOW 873T>C Pro291Pro
M0037961 JFBMIOKP_00006 4208 3 Skin 0.27 protein_coding synonymous_variant LOW 879C>T His293His
M0037962 JFBMIOKP_00006 4212 3 Skin 0.27 protein_coding missense_variant MODERATE 883A>G Thr295Ala
M0037963 JFBMIOKP_00012 12870 3 Skin 0.27 protein_coding synonymous_variant LOW 1017T>C Asp339Asp
M0037964 JFBMIOKP_00012 12873 3 Skin 0.27 protein_coding synonymous_variant LOW 1014T>C Asp338Asp
M0037965 JFBMIOKP_00003 1404 3 Skin 0.27 protein_coding synonymous_variant LOW 378G>C Thr126Thr
M0037966 JFBMIOKP_00007 5696 3 Skin 0.27 protein_coding synonymous_variant LOW 1155T>G Arg385Arg
M0037967 JFBMIOKP_00007 5828 3 Skin 0.27 protein_coding synonymous_variant LOW 1287C>G Gly429Gly
M0037968 JFBMIOKP_00007 5840 3 Skin 0.27 protein_coding synonymous_variant LOW 1299T>C Arg433Arg
M0037969 JFBMIOKP_00007 5844 3 Skin 0.27 protein_coding synonymous_variant LOW 1303C>T Leu435Leu
M0037970 JFBMIOKP_00007 5846 3 Skin 0.27 protein_coding synonymous_variant LOW 1305G>A Leu435Leu
M0037971 JFBMIOKP_00007 5847 3 Skin 0.27 protein_coding synonymous_variant LOW 1306C>T Leu436Leu
M0037972 JFBMIOKP_00007 5855 3 Skin 0.27 protein_coding synonymous_variant LOW 1314C>A Gly438Gly
M0037973 JFBMIOKP_00007 5861 3 Skin 0.27 protein_coding synonymous_variant LOW 1320G>T Arg440Arg
M0037974 JFBMIOKP_00007 5870 3 Skin 0.27 protein_coding synonymous_variant LOW 1329G>A Gln443Gln
M0037975 JFBMIOKP_00007 5912 3 Skin 0.27 protein_coding synonymous_variant LOW 1371C>T Ala457Ala
M0037976 JFBMIOKP_00005 2819 3 Skin 0.27 protein_coding synonymous_variant LOW 240T>C Ala80Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term