Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2346
  Reference Plasmid   1111525849767596_bin.1__k141_42430
  Reference Plasmid Size   4696
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0038010 IPJIEPNP_00001 898 3 Skin 0.75 protein_coding downstream_gene_variant MODIFIER *125A>G None
M0038011 IPJIEPNP_00001 967 4 Skin 1.00 protein_coding downstream_gene_variant MODIFIER *194T>G None
M0038012 IPJIEPNP_00001 973 4 Skin 1.00 protein_coding downstream_gene_variant MODIFIER *200A>C None
M0038013 IPJIEPNP_00001 1000 3 Skin 0.75 protein_coding downstream_gene_variant MODIFIER *227C>T None
M0038014 IPJIEPNP_00001 1024 3 Skin 0.75 protein_coding downstream_gene_variant MODIFIER *251C>A None
M0038015 IPJIEPNP_00002 1297 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -30G>C None
M0038016 IPJIEPNP_00002 1298 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -31T>A None
M0038017 IPJIEPNP_00002 1299 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -32T>A None
M0038018 IPJIEPNP_00002 1300 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -33G>C None
M0038019 IPJIEPNP_00003 1534 4 Skin 1.00 protein_coding synonymous_variant LOW 552T>G Thr184Thr
M0038020 IPJIEPNP_00003 2057 4 Skin 1.00 protein_coding missense_variant MODERATE 29T>C Val10Ala
M0038021 IPJIEPNP_00004 2157 3 Skin 0.75 protein_coding missense_variant MODERATE 305A>C Asp102Ala
M0038022 IPJIEPNP_00004 2218 3 Skin 0.75 protein_coding missense_variant MODERATE 244G>A Ala82Thr
M0038023 IPJIEPNP_00004 2229 4 Skin 1.00 protein_coding missense_variant MODERATE 233G>T Ser78Ile
M0038024 IPJIEPNP_00003 1527 3 Skin 0.75 protein_coding missense_variant MODERATE 559A>G Ser187Gly
M0038025 IPJIEPNP_00004 2342 3 Skin 0.75 protein_coding synonymous_variant LOW 120A>G Gln40Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term