Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2353
  Reference Plasmid   1111525849767596_bin.2__k141_31674
  Reference Plasmid Size   12542
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0040865 ANADEMCD_00004 8952 7 Skin 0.58 protein_coding upstream_gene_variant MODIFIER -4747T>C None
M0040866 ANADEMCD_00009 9023 6 Skin 0.50 protein_coding missense_variant MODERATE 191T>A Met64Lys
M0040867 ANADEMCD_00009 9072 6 Skin 0.50 protein_coding missense_variant MODERATE 142T>C Ser48Pro
M0040868 ANADEMCD_00010 10167 5 Skin 0.42 protein_coding synonymous_variant LOW 219T>C Asp73Asp
M0040869 ANADEMCD_00010 10183 3 Skin 0.25 protein_coding missense_variant MODERATE 203T>C Ile68Thr
M0040870 ANADEMCD_00011 10559 6 Skin 0.50 protein_coding synonymous_variant LOW 45T>C Tyr15Tyr
M0040871 ANADEMCD_00004 8821 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4616T>G None
M0040872 ANADEMCD_00009 9102 4 Skin 0.33 protein_coding missense_variant MODERATE 112G>C Glu38Gln
M0040873 ANADEMCD_00009 9186 4 Skin 0.33 protein_coding missense_variant MODERATE 28A>G Thr10Ala
M0040874 ANADEMCD_00009 9198 3 Skin 0.25 protein_coding missense_variant MODERATE 16T>G Phe6Val
M0040875 ANADEMCD_00009 9203 3 Skin 0.25 protein_coding missense_variant MODERATE 11C>A Thr4Lys
M0040876 ANADEMCD_00005 9249 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3985A>G None
M0040877 ANADEMCD_00006 10453 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -4197T>C None
M0040878 ANADEMCD_00006 10460 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4204A>G None
M0040879 ANADEMCD_00006 11208 4 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4952G>C None
M0040880 ANADEMCD_00007 11294 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -4034A>G None
M0040881 ANADEMCD_00012 11466 5 Skin 0.42 protein_coding synonymous_variant LOW 933T>C Asp311Asp
M0040882 ANADEMCD_00012 11549 4 Skin 0.33 protein_coding missense_variant MODERATE 850G>A Ala284Thr
M0040883 ANADEMCD_00012 11551 4 Skin 0.33 protein_coding missense_variant MODERATE 848C>G Thr283Ser
M0040884 ANADEMCD_00012 11797 6 Skin 0.50 protein_coding missense_variant MODERATE 602T>C Val201Ala
M0040885 ANADEMCD_00012 11991 4 Skin 0.33 protein_coding synonymous_variant LOW 408T>C Ser136Ser
M0040886 ANADEMCD_00012 12277 3 Skin 0.25 protein_coding missense_variant MODERATE 122G>A Gly41Glu
M0040887 ANADEMCD_00005 4623 3 Skin 0.25 protein_coding synonymous_variant LOW 642T>C Thr214Thr
M0040888 ANADEMCD_00005 4638 3 Skin 0.25 protein_coding synonymous_variant LOW 627T>C Asp209Asp
M0040889 ANADEMCD_00005 5223 3 Skin 0.25 protein_coding missense_variant MODERATE 42A>G Ile14Met
M0040890 ANADEMCD_00006 5483 3 Skin 0.25 protein_coding synonymous_variant LOW 774T>C Asp258Asp
M0040891 ANADEMCD_00009 9076 3 Skin 0.25 protein_coding missense_variant MODERATE 138T>G Ile46Met
M0040892 ANADEMCD_00006 10487 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4231G>A None
M0040893 ANADEMCD_00011 10745 3 Skin 0.25 protein_coding synonymous_variant LOW 231G>C Leu77Leu
M0040894 ANADEMCD_00006 11240 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4984A>G None
M0040895 ANADEMCD_00012 11430 3 Skin 0.25 protein_coding synonymous_variant LOW 969C>T Val323Val
M0040896 ANADEMCD_00012 11451 3 Skin 0.25 protein_coding synonymous_variant LOW 948C>T Leu316Leu
M0040897 ANADEMCD_00012 11892 3 Skin 0.25 protein_coding synonymous_variant LOW 507G>T Arg169Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term