Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2358
  Reference Plasmid   1111525849767822_bin.10__k141_20705
  Reference Plasmid Size   4059
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0040903 ADOLODIJ_00001 450 11 Skin 0.55 protein_coding missense_variant MODERATE 352T>C Tyr118His
M0040904 ADOLODIJ_00001 457 11 Skin 0.55 protein_coding synonymous_variant LOW 345A>G Arg115Arg
M0040905 ADOLODIJ_00002 863 18 Skin 0.90 protein_coding missense_variant MODERATE 271T>C Trp91Arg
M0040906 ADOLODIJ_00002 876 10 Skin 0.50 protein_coding synonymous_variant LOW 258C>T His86His
M0040907 ADOLODIJ_00002 882 10 Skin 0.50 protein_coding synonymous_variant LOW 252T>G Ala84Ala
M0040908 ADOLODIJ_00002 883 10 Skin 0.50 protein_coding missense_variant MODERATE 251C>T Ala84Val
M0040909 ADOLODIJ_00002 885 10 Skin 0.50 protein_coding synonymous_variant LOW 249T>G Gly83Gly
M0040910 ADOLODIJ_00002 891 10 Skin 0.50 protein_coding synonymous_variant LOW 243C>T Gly81Gly
M0040911 ADOLODIJ_00002 897 10 Skin 0.50 protein_coding synonymous_variant LOW 237T>C Ala79Ala
M0040912 ADOLODIJ_00002 979 6 Skin 0.30 protein_coding missense_variant MODERATE 155T>C Leu52Pro
M0040913 ADOLODIJ_00001 1188 4 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -387G>A None
M0040914 ADOLODIJ_00001 1219 5 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -418G>T None
M0040915 ADOLODIJ_00003 1673 15 Skin 0.75 protein_coding synonymous_variant LOW 597T>C Leu199Leu
M0040916 ADOLODIJ_00003 1997 6 Skin 0.30 protein_coding synonymous_variant LOW 273G>T Ala91Ala
M0040917 ADOLODIJ_00003 2089 16 Skin 0.80 protein_coding missense_variant MODERATE 181T>C Ser61Pro
M0040918 ADOLODIJ_00003 2243 18 Skin 0.90 protein_coding synonymous_variant LOW 27A>G Arg9Arg
M0040919 ADOLODIJ_00003 2251 10 Skin 0.50 protein_coding synonymous_variant LOW 19C>T Leu7Leu
M0040920 ADOLODIJ_00001 2275 11 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -1474T>G None
M0040921 ADOLODIJ_00001 2353 17 Skin 0.85 protein_coding upstream_gene_variant MODIFIER -1552C>T None
M0040922 ADOLODIJ_00001 2364 17 Skin 0.85 protein_coding upstream_gene_variant MODIFIER -1563C>G None
M0040923 ADOLODIJ_00001 2847 10 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2046T>C None
M0040924 ADOLODIJ_00001 2860 10 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2059A>G None
M0040925 ADOLODIJ_00001 2964 19 Skin 0.95 protein_coding upstream_gene_variant MODIFIER -2163C>T None
M0040926 ADOLODIJ_00001 2995 19 Skin 0.95 protein_coding upstream_gene_variant MODIFIER -2194A>G None
M0040927 ADOLODIJ_00004 3096 7 Skin 0.35 protein_coding stop_lost&splice_region_variant HIGH 369A>G Ter123Trpext*?
M0040928 ADOLODIJ_00004 3211 8 Skin 0.40 protein_coding missense_variant MODERATE 254A>C Asn85Thr
M0040929 ADOLODIJ_00004 3225 8 Skin 0.40 protein_coding synonymous_variant LOW 240G>C Ala80Ala
M0040930 ADOLODIJ_00004 3227 8 Skin 0.40 protein_coding missense_variant MODERATE 238G>A Ala80Thr
M0040931 ADOLODIJ_00004 3243 7 Skin 0.35 protein_coding synonymous_variant LOW 222T>A Ala74Ala
M0040932 ADOLODIJ_00004 3245 7 Skin 0.35 protein_coding missense_variant MODERATE 220G>C Ala74Pro
M0040933 ADOLODIJ_00004 3317 7 Skin 0.35 protein_coding missense_variant MODERATE 148G>A Gly50Arg
M0040934 ADOLODIJ_00004 3322 6 Skin 0.30 protein_coding missense_variant MODERATE 143T>C Val48Ala
M0040935 ADOLODIJ_00004 3370 8 Skin 0.40 protein_coding missense_variant MODERATE 95C>T Thr32Ile
M0040936 ADOLODIJ_00001 555 11 Skin 0.55 protein_coding missense_variant MODERATE 247G>A Asp83Asn
M0040937 ADOLODIJ_00001 559 12 Skin 0.60 protein_coding synonymous_variant LOW 243C>T Leu81Leu
M0040938 ADOLODIJ_00001 562 12 Skin 0.60 protein_coding synonymous_variant LOW 240A>G Gln80Gln
M0040939 ADOLODIJ_00001 607 4 Skin 0.20 protein_coding synonymous_variant LOW 195T>A Ala65Ala
M0040940 ADOLODIJ_00001 640 3 Skin 0.15 protein_coding synonymous_variant LOW 162T>C Val54Val
M0040941 ADOLODIJ_00002 1125 6 Skin 0.30 protein_coding stop_gained HIGH 9G>A Trp3*
M0040942 ADOLODIJ_00001 224 7 Skin 0.35 protein_coding downstream_gene_variant MODIFIER *5A>G None
M0040943 ADOLODIJ_00001 262 3 Skin 0.15 protein_coding synonymous_variant LOW 540T>C Asp180Asp
M0040944 ADOLODIJ_00001 353 8 Skin 0.40 protein_coding missense_variant MODERATE 449G>A Gly150Glu
M0040945 ADOLODIJ_00001 661 9 Skin 0.45 protein_coding synonymous_variant LOW 141G>A Ala47Ala
M0040946 ADOLODIJ_00001 739 4 Skin 0.20 protein_coding synonymous_variant LOW 63C>T Asp21Asp
M0040947 ADOLODIJ_00002 1087 3 Skin 0.15 protein_coding missense_variant MODERATE 47C>T Ser16Leu
M0040948 ADOLODIJ_00001 3000 4 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2199A>G None
M0040949 ADOLODIJ_00001 3004 4 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2203C>T None
M0040950 ADOLODIJ_00002 836 6 Skin 0.30 protein_coding missense_variant MODERATE 298T>C Cys100Arg
M0040951 ADOLODIJ_00003 1820 8 Skin 0.40 protein_coding synonymous_variant LOW 450C>T Ser150Ser
M0040952 ADOLODIJ_00004 3462 5 Skin 0.25 protein_coding start_lost HIGH 3G>A Met1?
M0040953 ADOLODIJ_00004 3463 5 Skin 0.25 protein_coding start_lost HIGH 2T>C Met1?
M0040954 ADOLODIJ_00001 3510 4 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2709T>C None
M0040955 ADOLODIJ_00001 3637 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2836G>A None
M0040956 ADOLODIJ_00001 3670 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2869C>T None
M0040957 ADOLODIJ_00003 1928 4 Skin 0.20 protein_coding synonymous_variant LOW 342C>A Gly114Gly
M0040958 ADOLODIJ_00001 2685 4 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -1884T>C None
M0040959 ADOLODIJ_00004 3406 4 Skin 0.20 protein_coding missense_variant MODERATE 59C>T Ala20Val
M0040960 ADOLODIJ_00004 3408 4 Skin 0.20 protein_coding synonymous_variant LOW 57T>G Leu19Leu
M0040961 ADOLODIJ_00001 592 3 Skin 0.15 protein_coding synonymous_variant LOW 210G>A Pro70Pro
M0040962 ADOLODIJ_00002 1064 3 Skin 0.15 protein_coding missense_variant MODERATE 70G>A Val24Ile
M0040963 ADOLODIJ_00001 1317 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -516G>A None
M0040964 ADOLODIJ_00003 1751 3 Skin 0.15 protein_coding synonymous_variant LOW 519A>G Thr173Thr
M0040965 ADOLODIJ_00003 2002 3 Skin 0.15 protein_coding missense_variant MODERATE 268G>A Ala90Thr
M0040966 ADOLODIJ_00003 2173 3 Skin 0.15 protein_coding missense_variant MODERATE 97A>G Ile33Val
M0040967 ADOLODIJ_00001 430 3 Skin 0.15 protein_coding synonymous_variant LOW 372T>A Thr124Thr
M0040968 ADOLODIJ_00001 431 3 Skin 0.15 protein_coding missense_variant MODERATE 371C>T Thr124Ile
M0040969 ADOLODIJ_00001 456 3 Skin 0.15 protein_coding synonymous_variant LOW 346C>T Leu116Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term