Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2361
  Reference Plasmid   1111525849768046_bin.36__k141_218550
  Reference Plasmid Size   4110
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0041348 EOCKHFCP_00001 1458 10 Skin 0.71 protein_coding missense_variant MODERATE 2048T>C Met683Thr
M0041349 EOCKHFCP_00001 1464 10 Skin 0.71 protein_coding missense_variant MODERATE 2042A>C Asn681Thr
M0041350 EOCKHFCP_00001 1496 10 Skin 0.71 protein_coding synonymous_variant LOW 2010G>A Glu670Glu
M0041351 EOCKHFCP_00001 1551 9 Skin 0.64 protein_coding missense_variant MODERATE 1955A>T Gln652Leu
M0041352 EOCKHFCP_00001 1558 9 Skin 0.64 protein_coding synonymous_variant LOW 1948C>T Leu650Leu
M0041353 EOCKHFCP_00001 1613 9 Skin 0.64 protein_coding synonymous_variant LOW 1893A>G Leu631Leu
M0041354 EOCKHFCP_00001 1619 9 Skin 0.64 protein_coding missense_variant MODERATE 1887G>T Lys629Asn
M0041355 EOCKHFCP_00001 2082 9 Skin 0.64 protein_coding missense_variant MODERATE 1424T>C Val475Ala
M0041356 EOCKHFCP_00001 2419 9 Skin 0.64 protein_coding missense_variant MODERATE 1087G>A Ala363Thr
M0041357 EOCKHFCP_00001 387 7 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *179A>G None
M0041358 EOCKHFCP_00001 513 6 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *53C>T None
M0041359 EOCKHFCP_00001 974 6 Skin 0.43 protein_coding synonymous_variant LOW 2532A>G Lys844Lys
M0041360 EOCKHFCP_00001 1390 7 Skin 0.50 protein_coding missense_variant MODERATE 2116C>G Gln706Glu
M0041361 EOCKHFCP_00001 1841 3 Skin 0.21 protein_coding synonymous_variant LOW 1665A>G Lys555Lys
M0041362 EOCKHFCP_00001 1850 3 Skin 0.21 protein_coding synonymous_variant LOW 1656T>C Arg552Arg
M0041363 EOCKHFCP_00001 1879 3 Skin 0.21 protein_coding missense_variant MODERATE 1627T>C Tyr543His
M0041364 EOCKHFCP_00001 1949 3 Skin 0.21 protein_coding synonymous_variant LOW 1557G>A Gln519Gln
M0041365 EOCKHFCP_00001 1262 5 Skin 0.36 protein_coding synonymous_variant LOW 2244C>T Tyr748Tyr
M0041366 EOCKHFCP_00001 1314 5 Skin 0.36 protein_coding missense_variant MODERATE 2192G>A Ser731Asn
M0041367 EOCKHFCP_00001 1322 3 Skin 0.21 protein_coding synonymous_variant LOW 2184A>C Thr728Thr
M0041368 EOCKHFCP_00002 3974 3 Skin 0.21 protein_coding missense_variant MODERATE 103T>A Ser35Thr
M0041369 EOCKHFCP_00002 3987 3 Skin 0.21 protein_coding synonymous_variant LOW 90C>T His30His
M0041370 EOCKHFCP_00001 53 3 Skin 0.21 protein_coding downstream_gene_variant MODIFIER *513G>A None
M0041371 EOCKHFCP_00001 105 4 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *461C>T None
M0041372 EOCKHFCP_00001 120 4 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *446T>G None
M0041373 EOCKHFCP_00001 126 4 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *440T>A None
M0041374 EOCKHFCP_00001 245 4 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *321A>T None
M0041375 EOCKHFCP_00001 246 4 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *320T>C None
M0041376 EOCKHFCP_00001 249 4 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *317A>G None
M0041377 EOCKHFCP_00001 698 4 Skin 0.29 protein_coding synonymous_variant LOW 2808A>G Glu936Glu
M0041378 EOCKHFCP_00001 758 3 Skin 0.21 protein_coding synonymous_variant LOW 2748T>C Tyr916Tyr
M0041379 EOCKHFCP_00001 1748 3 Skin 0.21 protein_coding synonymous_variant LOW 1758T>C Ile586Ile
M0041380 EOCKHFCP_00001 1756 3 Skin 0.21 protein_coding missense_variant MODERATE 1750C>A His584Asn
M0041381 EOCKHFCP_00001 1762 3 Skin 0.21 protein_coding synonymous_variant LOW 1744T>C Leu582Leu
M0041382 EOCKHFCP_00001 1769 3 Skin 0.21 protein_coding missense_variant MODERATE 1737A>T Leu579Phe
M0041383 EOCKHFCP_00001 1771 3 Skin 0.21 protein_coding synonymous_variant LOW 1735T>C Leu579Leu
M0041384 EOCKHFCP_00001 2120 4 Skin 0.29 protein_coding synonymous_variant LOW 1386G>A Leu462Leu
M0041385 EOCKHFCP_00001 2342 4 Skin 0.29 protein_coding synonymous_variant LOW 1164T>C Asn388Asn
M0041386 EOCKHFCP_00001 2498 3 Skin 0.21 protein_coding synonymous_variant LOW 1008A>T Ile336Ile
M0041387 EOCKHFCP_00001 2768 4 Skin 0.29 protein_coding synonymous_variant LOW 738C>T His246His
M0041388 EOCKHFCP_00001 3287 3 Skin 0.21 protein_coding synonymous_variant LOW 219A>T Ser73Ser
M0041389 EOCKHFCP_00001 195 3 Skin 0.21 protein_coding downstream_gene_variant MODIFIER *371T>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term