Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2364
  Reference Plasmid   1111525849768046_bin.37__k141_107327
  Reference Plasmid Size   4023
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0119211 FHNOBLON_00002 84 7 Oral 0.70 protein_coding upstream_gene_variant MODIFIER -1213T>A None
M0119212 FHNOBLON_00002 135 6 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1162T>G None
M0119213 FHNOBLON_00002 165 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -1132A>T None
M0119214 FHNOBLON_00002 207 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1090G>A None
M0119215 FHNOBLON_00002 219 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1078T>C None
M0119216 FHNOBLON_00002 258 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -1039A>G None
M0119217 FHNOBLON_00002 288 6 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1009T>C None
M0119218 FHNOBLON_00002 330 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -967G>A None
M0119219 FHNOBLON_00002 339 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -958C>T None
M0119220 FHNOBLON_00002 347 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -950T>C None
M0119221 FHNOBLON_00002 402 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -895A>G None
M0119222 FHNOBLON_00002 444 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -853A>T None
M0119223 FHNOBLON_00002 453 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -844C>T None
M0119224 FHNOBLON_00001 543 3 Oral 0.30 protein_coding missense_variant MODERATE 173T>G Leu58Arg
M0119225 FHNOBLON_00001 666 3 Oral 0.30 protein_coding missense_variant MODERATE 50G>A Ser17Asn
M0119226 FHNOBLON_00001 741 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -26C>T None
M0119227 FHNOBLON_00001 780 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -65T>C None
M0119228 FHNOBLON_00001 902 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -187A>G None
M0119229 FHNOBLON_00001 999 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -284T>C None
M0119230 FHNOBLON_00001 1068 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -353G>T None
M0119231 FHNOBLON_00001 1257 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -542T>C None
M0119232 FHNOBLON_00001 1287 6 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -572C>T None
M0119233 FHNOBLON_00001 1290 6 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -575C>G None
M0119234 FHNOBLON_00002 1301 5 Oral 0.50 protein_coding missense_variant MODERATE 5T>C Leu2Pro
M0119235 FHNOBLON_00002 1338 6 Oral 0.60 protein_coding synonymous_variant LOW 42A>G Leu14Leu
M0119236 FHNOBLON_00002 1351 6 Oral 0.60 protein_coding missense_variant MODERATE 55T>A Ser19Thr
M0119237 FHNOBLON_00002 1397 6 Oral 0.60 protein_coding missense_variant MODERATE 101C>T Ser34Leu
M0119238 FHNOBLON_00003 1717 6 Oral 0.60 protein_coding synonymous_variant LOW 2229T>C Asp743Asp
M0119239 FHNOBLON_00003 1828 8 Oral 0.80 protein_coding synonymous_variant LOW 2118A>G Val706Val
M0119240 FHNOBLON_00003 1834 8 Oral 0.80 protein_coding synonymous_variant LOW 2112T>A Gly704Gly
M0119241 FHNOBLON_00003 1840 8 Oral 0.80 protein_coding synonymous_variant LOW 2106C>T Asn702Asn
M0119242 FHNOBLON_00003 1978 5 Oral 0.50 protein_coding synonymous_variant LOW 1968C>T Ile656Ile
M0119243 FHNOBLON_00003 1981 6 Oral 0.60 protein_coding synonymous_variant LOW 1965T>G Val655Val
M0119244 FHNOBLON_00003 2011 3 Oral 0.30 protein_coding synonymous_variant LOW 1935C>T Asp645Asp
M0119245 FHNOBLON_00003 2083 5 Oral 0.50 protein_coding synonymous_variant LOW 1863G>T Leu621Leu
M0119246 FHNOBLON_00003 2233 9 Oral 0.90 protein_coding synonymous_variant LOW 1713T>C Asn571Asn
M0119247 FHNOBLON_00003 2677 9 Oral 0.90 protein_coding synonymous_variant LOW 1269A>G Glu423Glu
M0119248 FHNOBLON_00003 2806 9 Oral 0.90 protein_coding synonymous_variant LOW 1140C>T Arg380Arg
M0119249 FHNOBLON_00003 2809 9 Oral 0.90 protein_coding synonymous_variant LOW 1137C>T Gly379Gly
M0119250 FHNOBLON_00003 2968 6 Oral 0.60 protein_coding synonymous_variant LOW 978C>T Leu326Leu
M0119251 FHNOBLON_00003 3091 3 Oral 0.30 protein_coding synonymous_variant LOW 855C>T Asn285Asn
M0119252 FHNOBLON_00003 3121 9 Oral 0.90 protein_coding synonymous_variant LOW 825C>T Phe275Phe
M0119253 FHNOBLON_00003 3195 6 Oral 0.60 protein_coding missense_variant MODERATE 751A>G Ile251Val
M0119254 FHNOBLON_00003 3571 9 Oral 0.90 protein_coding synonymous_variant LOW 375G>A Gln125Gln
M0119255 FHNOBLON_00003 3784 7 Oral 0.70 protein_coding synonymous_variant LOW 162A>G Val54Val
M0119256 FHNOBLON_00002 285 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -1012T>A None
M0119257 FHNOBLON_00001 495 7 Oral 0.70 protein_coding missense_variant MODERATE 221A>G Lys74Arg
M0119258 FHNOBLON_00001 722 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -7G>T None
M0119259 FHNOBLON_00001 735 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -20G>A None
M0119260 FHNOBLON_00001 936 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -221C>T None
M0119261 FHNOBLON_00003 2125 7 Oral 0.70 protein_coding synonymous_variant LOW 1821T>C Tyr607Tyr
M0119262 FHNOBLON_00003 2143 6 Oral 0.60 protein_coding synonymous_variant LOW 1803T>C Tyr601Tyr
M0119263 FHNOBLON_00003 2302 6 Oral 0.60 protein_coding synonymous_variant LOW 1644T>A Thr548Thr
M0119264 FHNOBLON_00003 2389 3 Oral 0.30 protein_coding synonymous_variant LOW 1557C>T Arg519Arg
M0119265 FHNOBLON_00003 2409 6 Oral 0.60 protein_coding synonymous_variant LOW 1537C>T Leu513Leu
M0119266 FHNOBLON_00003 2421 8 Oral 0.80 protein_coding missense_variant MODERATE 1525A>G Ile509Val
M0119267 FHNOBLON_00003 2557 8 Oral 0.80 protein_coding synonymous_variant LOW 1389T>C Phe463Phe
M0119268 FHNOBLON_00003 2593 8 Oral 0.80 protein_coding synonymous_variant LOW 1353T>G Leu451Leu
M0119269 FHNOBLON_00003 2595 8 Oral 0.80 protein_coding missense_variant MODERATE 1351C>T Leu451Phe
M0119270 FHNOBLON_00003 2734 5 Oral 0.50 protein_coding synonymous_variant LOW 1212G>A Lys404Lys
M0119271 FHNOBLON_00003 2920 7 Oral 0.70 protein_coding synonymous_variant LOW 1026C>T Ser342Ser
M0119272 FHNOBLON_00003 2971 8 Oral 0.80 protein_coding synonymous_variant LOW 975T>A Ala325Ala
M0119273 FHNOBLON_00003 2977 7 Oral 0.70 protein_coding synonymous_variant LOW 969T>C Val323Val
M0119274 FHNOBLON_00003 2980 8 Oral 0.80 protein_coding synonymous_variant LOW 966A>T Thr322Thr
M0119275 FHNOBLON_00003 3052 6 Oral 0.60 protein_coding synonymous_variant LOW 894C>T Asn298Asn
M0119276 FHNOBLON_00003 3076 5 Oral 0.50 protein_coding synonymous_variant LOW 870T>A Thr290Thr
M0119277 FHNOBLON_00003 3301 6 Oral 0.60 protein_coding synonymous_variant LOW 645T>C Gly215Gly
M0119278 FHNOBLON_00003 3415 6 Oral 0.60 protein_coding synonymous_variant LOW 531A>T Gly177Gly
M0119279 FHNOBLON_00003 3541 8 Oral 0.80 protein_coding synonymous_variant LOW 405A>G Gln135Gln
M0119280 FHNOBLON_00003 3640 6 Oral 0.60 protein_coding synonymous_variant LOW 306T>C Ser102Ser
M0119281 FHNOBLON_00003 3859 6 Oral 0.60 protein_coding synonymous_variant LOW 87G>C Ala29Ala
M0119282 FHNOBLON_00003 3922 8 Oral 0.80 protein_coding synonymous_variant LOW 24C>T Asp8Asp
M0119283 FHNOBLON_00001 3949 8 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -3234C>T None
M0119284 FHNOBLON_00003 1750 3 Oral 0.30 protein_coding synonymous_variant LOW 2196C>A Thr732Thr
M0119285 FHNOBLON_00003 2440 4 Oral 0.40 protein_coding synonymous_variant LOW 1506T>A Ala502Ala
M0119286 FHNOBLON_00003 2821 3 Oral 0.30 protein_coding synonymous_variant LOW 1125T>C Cys375Cys
M0119287 FHNOBLON_00003 2887 3 Oral 0.30 protein_coding synonymous_variant LOW 1059G>A Glu353Glu
M0119288 FHNOBLON_00003 2938 3 Oral 0.30 protein_coding synonymous_variant LOW 1008T>C Tyr336Tyr
M0119289 FHNOBLON_00003 2979 4 Oral 0.40 protein_coding missense_variant MODERATE 967G>A Val323Ile
M0119290 FHNOBLON_00003 3445 3 Oral 0.30 protein_coding synonymous_variant LOW 501T>C Asp167Asp
M0119291 FHNOBLON_00003 3448 3 Oral 0.30 protein_coding synonymous_variant LOW 498C>T Ile166Ile
M0119292 FHNOBLON_00003 3451 3 Oral 0.30 protein_coding synonymous_variant LOW 495T>C Asn165Asn
M0119293 FHNOBLON_00003 3601 3 Oral 0.30 protein_coding synonymous_variant LOW 345G>A Glu115Glu
M0119294 FHNOBLON_00003 3940 5 Oral 0.50 protein_coding synonymous_variant LOW 6C>T Asn2Asn
M0119295 FHNOBLON_00002 1428 3 Oral 0.30 protein_coding synonymous_variant LOW 132A>G Glu44Glu
M0119296 FHNOBLON_00002 1439 4 Oral 0.40 protein_coding missense_variant MODERATE 143T>A Val48Glu
M0119297 FHNOBLON_00003 3028 3 Oral 0.30 protein_coding synonymous_variant LOW 918T>A Thr306Thr
M0119298 FHNOBLON_00002 315 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -982T>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term