Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2369
  Reference Plasmid   1111525849768046_bin.37__k141_118294
  Reference Plasmid Size   4432
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0119460 KKADMCBN_00001 333 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1510G>T None
M0119461 KKADMCBN_00001 335 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1508C>T None
M0119462 KKADMCBN_00001 355 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1488C>T None
M0119463 KKADMCBN_00001 357 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1486G>T None
M0119464 KKADMCBN_00001 363 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1480A>C None
M0119465 KKADMCBN_00001 542 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1301T>G None
M0119466 KKADMCBN_00001 582 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1261G>A None
M0119467 KKADMCBN_00001 597 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1246A>G None
M0119468 KKADMCBN_00001 598 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1245C>T None
M0119469 KKADMCBN_00001 603 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1240A>T None
M0119470 KKADMCBN_00001 615 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1228C>A None
M0119471 KKADMCBN_00001 638 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1205A>G None
M0119472 KKADMCBN_00001 697 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1146T>G None
M0119473 KKADMCBN_00001 1455 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -388A>T None
M0119474 KKADMCBN_00001 1497 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -346T>C None
M0119475 KKADMCBN_00001 1545 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -298C>T None
M0119476 KKADMCBN_00001 1869 3 Oral 0.60 protein_coding synonymous_variant LOW 27T>C Thr9Thr
M0119477 KKADMCBN_00001 1938 3 Oral 0.60 protein_coding synonymous_variant LOW 96T>A Ala32Ala
M0119478 KKADMCBN_00001 2003 4 Oral 0.80 protein_coding missense_variant MODERATE 161T>C Val54Ala
M0119479 KKADMCBN_00001 2142 4 Oral 0.80 protein_coding synonymous_variant LOW 300C>T Ser100Ser
M0119480 KKADMCBN_00001 2143 4 Oral 0.80 protein_coding missense_variant MODERATE 301A>G Ile101Val
M0119481 KKADMCBN_00001 2147 3 Oral 0.60 protein_coding missense_variant MODERATE 305G>A Gly102Glu
M0119482 KKADMCBN_00001 2154 4 Oral 0.80 protein_coding synonymous_variant LOW 312T>C Ala104Ala
M0119483 KKADMCBN_00001 2163 4 Oral 0.80 protein_coding synonymous_variant LOW 321A>G Ser107Ser
M0119484 KKADMCBN_00001 2168 4 Oral 0.80 protein_coding missense_variant MODERATE 326C>T Ser109Phe
M0119485 KKADMCBN_00001 2181 3 Oral 0.60 protein_coding synonymous_variant LOW 339C>T Phe113Phe
M0119486 KKADMCBN_00001 2196 4 Oral 0.80 protein_coding synonymous_variant LOW 354A>G Lys118Lys
M0119487 KKADMCBN_00001 2227 4 Oral 0.80 protein_coding missense_variant MODERATE 385T>C Tyr129His
M0119488 KKADMCBN_00001 2235 3 Oral 0.60 protein_coding synonymous_variant LOW 393A>T Ala131Ala
M0119489 KKADMCBN_00001 2262 3 Oral 0.60 protein_coding synonymous_variant LOW 420A>G Leu140Leu
M0119490 KKADMCBN_00001 2286 4 Oral 0.80 protein_coding synonymous_variant LOW 444C>T Ile148Ile
M0119491 KKADMCBN_00002 2318 4 Oral 0.80 protein_coding synonymous_variant LOW 18T>G Arg6Arg
M0119492 KKADMCBN_00002 2333 4 Oral 0.80 protein_coding synonymous_variant LOW 33C>T Phe11Phe
M0119493 KKADMCBN_00002 2396 4 Oral 0.80 protein_coding synonymous_variant LOW 96T>C Leu32Leu
M0119494 KKADMCBN_00002 2426 4 Oral 0.80 protein_coding synonymous_variant LOW 126C>T Tyr42Tyr
M0119495 KKADMCBN_00002 2429 4 Oral 0.80 protein_coding synonymous_variant LOW 129A>T Ser43Ser
M0119496 KKADMCBN_00002 2432 4 Oral 0.80 protein_coding synonymous_variant LOW 132T>A Thr44Thr
M0119497 KKADMCBN_00002 2535 4 Oral 0.80 protein_coding missense_variant MODERATE 235T>A Ser79Thr
M0119498 KKADMCBN_00002 2636 4 Oral 0.80 protein_coding synonymous_variant LOW 336G>T Ala112Ala
M0119499 KKADMCBN_00002 2669 3 Oral 0.60 protein_coding missense_variant MODERATE 369A>G Ile123Met
M0119500 KKADMCBN_00003 2749 3 Oral 0.60 protein_coding synonymous_variant LOW 54A>G Leu18Leu
M0119501 KKADMCBN_00003 2929 3 Oral 0.60 protein_coding synonymous_variant LOW 234T>C Asp78Asp
M0119502 KKADMCBN_00003 3001 3 Oral 0.60 protein_coding synonymous_variant LOW 306C>T Tyr102Tyr
M0119503 KKADMCBN_00003 3031 4 Oral 0.80 protein_coding synonymous_variant LOW 336T>A Leu112Leu
M0119504 KKADMCBN_00003 3056 4 Oral 0.80 protein_coding missense_variant MODERATE 361A>G Ile121Val
M0119505 KKADMCBN_00003 3088 4 Oral 0.80 protein_coding synonymous_variant LOW 393C>T Ile131Ile
M0119506 KKADMCBN_00004 3427 3 Oral 0.60 protein_coding synonymous_variant LOW 99G>T Ala33Ala
M0119507 KKADMCBN_00004 3436 3 Oral 0.60 protein_coding synonymous_variant LOW 108T>C Tyr36Tyr
M0119508 KKADMCBN_00004 3442 3 Oral 0.60 protein_coding missense_variant MODERATE 114T>G Cys38Trp
M0119509 KKADMCBN_00004 3472 3 Oral 0.60 protein_coding synonymous_variant LOW 144T>C Asn48Asn
M0119510 KKADMCBN_00004 3490 3 Oral 0.60 protein_coding synonymous_variant LOW 162T>C Asp54Asp
M0119511 KKADMCBN_00004 3784 3 Oral 0.60 protein_coding synonymous_variant LOW 456C>T Phe152Phe
M0119512 KKADMCBN_00004 3796 3 Oral 0.60 protein_coding synonymous_variant LOW 468A>G Leu156Leu
M0119513 KKADMCBN_00004 3817 3 Oral 0.60 protein_coding synonymous_variant LOW 489T>A Ala163Ala
M0119514 KKADMCBN_00004 4085 3 Oral 0.60 protein_coding missense_variant MODERATE 757A>G Thr253Ala
M0119515 KKADMCBN_00004 4110 3 Oral 0.60 protein_coding missense_variant MODERATE 782A>G Lys261Arg
M0119516 KKADMCBN_00004 4150 3 Oral 0.60 protein_coding synonymous_variant LOW 822C>T Asp274Asp
M0119517 KKADMCBN_00001 4178 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1865G>A None
M0119518 KKADMCBN_00001 4192 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1879G>A None
M0119519 KKADMCBN_00001 4213 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1900T>A None
M0119520 KKADMCBN_00001 4279 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1966A>G None
M0119521 KKADMCBN_00001 4281 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1968A>G None
M0119522 KKADMCBN_00001 4285 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1972C>T None
M0119523 KKADMCBN_00001 4288 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1975T>G None
M0119524 KKADMCBN_00003 2863 3 Oral 0.60 protein_coding synonymous_variant LOW 168T>C Ser56Ser
M0119525 KKADMCBN_00003 2871 3 Oral 0.60 protein_coding missense_variant MODERATE 176G>C Ser59Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term