Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2370
  Reference Plasmid   1111525849768046_bin.37__k141_121883
  Reference Plasmid Size   3774
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0119526 KCBMKCPN_00001 1943 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *1273A>C None
M0119527 KCBMKCPN_00001 1960 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *1256A>C None
M0119528 KCBMKCPN_00001 2371 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *845T>C None
M0119529 KCBMKCPN_00001 2500 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *716T>C None
M0119530 KCBMKCPN_00001 2518 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *698T>C None
M0119531 KCBMKCPN_00001 2605 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *611A>T None
M0119532 KCBMKCPN_00001 2692 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *524C>A None
M0119533 KCBMKCPN_00001 2797 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *419T>C None
M0119534 KCBMKCPN_00001 2830 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *386T>C None
M0119535 KCBMKCPN_00001 3134 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *82G>A None
M0119536 KCBMKCPN_00001 3226 3 Oral 0.38 protein_coding missense_variant MODERATE 467T>G Leu156Arg
M0119537 KCBMKCPN_00001 3310 4 Oral 0.50 protein_coding missense_variant MODERATE 383T>C Leu128Ser
M0119538 KCBMKCPN_00001 3388 3 Oral 0.38 protein_coding missense_variant MODERATE 305A>G His102Arg
M0119539 KCBMKCPN_00001 3445 3 Oral 0.38 protein_coding missense_variant MODERATE 248T>C Ile83Thr
M0119540 KCBMKCPN_00001 3448 4 Oral 0.50 protein_coding missense_variant MODERATE 245G>A Ser82Asn
M0119541 KCBMKCPN_00001 3484 4 Oral 0.50 protein_coding missense_variant MODERATE 209C>T Pro70Leu
M0119542 KCBMKCPN_00001 3511 4 Oral 0.50 protein_coding missense_variant MODERATE 182T>C Leu61Pro
M0119543 KCBMKCPN_00001 198 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *3018A>C None
M0119544 KCBMKCPN_00001 206 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *3010A>C None
M0119545 KCBMKCPN_00001 212 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *3004G>C None
M0119546 KCBMKCPN_00001 256 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2960T>C None
M0119547 KCBMKCPN_00001 268 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *2948C>T None
M0119548 KCBMKCPN_00001 274 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *2942C>A None
M0119549 KCBMKCPN_00001 298 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *2918G>T None
M0119550 KCBMKCPN_00001 442 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2774T>C None
M0119551 KCBMKCPN_00001 443 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2773G>C None
M0119552 KCBMKCPN_00001 444 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2772G>A None
M0119553 KCBMKCPN_00001 457 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2759G>T None
M0119554 KCBMKCPN_00001 670 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *2546C>T None
M0119555 KCBMKCPN_00001 826 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2390T>C None
M0119556 KCBMKCPN_00001 927 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2289A>C None
M0119557 KCBMKCPN_00001 938 6 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *2278A>C None
M0119558 KCBMKCPN_00001 987 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *2229T>C None
M0119559 KCBMKCPN_00001 1210 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *2006A>G None
M0119560 KCBMKCPN_00001 1213 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *2003G>A None
M0119561 KCBMKCPN_00001 1234 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *1982T>C None
M0119562 KCBMKCPN_00001 1312 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *1904A>T None
M0119563 KCBMKCPN_00001 1340 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *1876G>C None
M0119564 KCBMKCPN_00001 1348 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *1868T>C None
M0119565 KCBMKCPN_00001 1465 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *1751T>C None
M0119566 KCBMKCPN_00001 1466 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *1750A>T None
M0119567 KCBMKCPN_00001 1648 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *1568T>C None
M0119568 KCBMKCPN_00001 1699 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *1517T>C None
M0119569 KCBMKCPN_00001 2395 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *821T>A None
M0119570 KCBMKCPN_00001 2761 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *455A>T None
M0119571 KCBMKCPN_00001 1011 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *2205A>G None
M0119572 KCBMKCPN_00001 1153 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *2063C>T None
M0119573 KCBMKCPN_00001 733 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *2483C>T None
M0119574 KCBMKCPN_00001 978 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *2238C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term