Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2371
  Reference Plasmid   1111525849768046_bin.37__k141_124737
  Reference Plasmid Size   2163
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0119575 NLMOBHDN_00001 505 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *111A>G None
M0119576 NLMOBHDN_00001 564 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *52A>C None
M0119577 NLMOBHDN_00001 569 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *47C>A None
M0119578 NLMOBHDN_00001 615 5 Oral 0.71 protein_coding downstream_gene_variant MODIFIER *1A>G None
M0119579 NLMOBHDN_00001 1024 3 Oral 0.43 protein_coding synonymous_variant LOW 1089A>G Leu363Leu
M0119580 NLMOBHDN_00001 1063 5 Oral 0.71 protein_coding synonymous_variant LOW 1050A>G Glu350Glu
M0119581 NLMOBHDN_00001 1138 5 Oral 0.71 protein_coding synonymous_variant LOW 975G>T Thr325Thr
M0119582 NLMOBHDN_00001 1198 4 Oral 0.57 protein_coding synonymous_variant LOW 915A>G Glu305Glu
M0119583 NLMOBHDN_00001 1209 3 Oral 0.43 protein_coding missense_variant MODERATE 904T>A Ser302Thr
M0119584 NLMOBHDN_00001 1435 4 Oral 0.57 protein_coding synonymous_variant LOW 678C>T Val226Val
M0119585 NLMOBHDN_00001 1546 4 Oral 0.57 protein_coding synonymous_variant LOW 567A>C Ile189Ile
M0119586 NLMOBHDN_00001 1588 4 Oral 0.57 protein_coding synonymous_variant LOW 525G>A Gln175Gln
M0119587 NLMOBHDN_00001 1591 4 Oral 0.57 protein_coding synonymous_variant LOW 522A>G Glu174Glu
M0119588 NLMOBHDN_00001 1606 4 Oral 0.57 protein_coding synonymous_variant LOW 507A>T Leu169Leu
M0119589 NLMOBHDN_00001 1729 4 Oral 0.57 protein_coding synonymous_variant LOW 384T>C Tyr128Tyr
M0119590 NLMOBHDN_00001 1753 3 Oral 0.43 protein_coding synonymous_variant LOW 360A>G Thr120Thr
M0119591 NLMOBHDN_00001 1981 4 Oral 0.57 protein_coding synonymous_variant LOW 132T>C Asn44Asn
M0119592 NLMOBHDN_00001 1987 4 Oral 0.57 protein_coding synonymous_variant LOW 126C>A Ile42Ile
M0119593 NLMOBHDN_00001 1993 3 Oral 0.43 protein_coding synonymous_variant LOW 120C>T Phe40Phe
M0119594 NLMOBHDN_00001 1996 4 Oral 0.57 protein_coding synonymous_variant LOW 117C>T Asn39Asn
M0119595 NLMOBHDN_00001 2011 4 Oral 0.57 protein_coding synonymous_variant LOW 102C>T Cys34Cys
M0119596 NLMOBHDN_00001 253 4 Oral 0.57 protein_coding downstream_gene_variant MODIFIER *363A>G None
M0119597 NLMOBHDN_00001 339 4 Oral 0.57 protein_coding downstream_gene_variant MODIFIER *277C>T None
M0119598 NLMOBHDN_00001 363 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *253A>T None
M0119599 NLMOBHDN_00001 372 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *244T>A None
M0119600 NLMOBHDN_00001 374 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *242G>A None
M0119601 NLMOBHDN_00001 763 3 Oral 0.43 protein_coding synonymous_variant LOW 1350T>C Ala450Ala
M0119602 NLMOBHDN_00001 793 4 Oral 0.57 protein_coding synonymous_variant LOW 1320A>G Ala440Ala
M0119603 NLMOBHDN_00001 820 4 Oral 0.57 protein_coding synonymous_variant LOW 1293T>C Asn431Asn
M0119604 NLMOBHDN_00001 834 4 Oral 0.57 protein_coding missense_variant MODERATE 1279C>G Gln427Glu
M0119605 NLMOBHDN_00001 1288 4 Oral 0.57 protein_coding synonymous_variant LOW 825A>G Thr275Thr
M0119606 NLMOBHDN_00001 1615 3 Oral 0.43 protein_coding synonymous_variant LOW 498T>C Phe166Phe
M0119607 NLMOBHDN_00001 1842 3 Oral 0.43 protein_coding synonymous_variant LOW 271T>C Leu91Leu
M0119608 NLMOBHDN_00001 2086 3 Oral 0.43 protein_coding synonymous_variant LOW 27T>C Arg9Arg
M0119609 NLMOBHDN_00001 2092 3 Oral 0.43 protein_coding synonymous_variant LOW 21G>A Lys7Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term