Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2376
  Reference Plasmid   1111525849768046_bin.37__k141_133522
  Reference Plasmid Size   4252
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0120082 BDCIFKPM_00004 2624 3 Oral 0.60 protein_coding synonymous_variant LOW 477A>G Gly159Gly
M0120083 BDCIFKPM_00004 2633 3 Oral 0.60 protein_coding synonymous_variant LOW 468C>T Leu156Leu
M0120084 BDCIFKPM_00004 2711 3 Oral 0.60 protein_coding synonymous_variant LOW 390A>T Val130Val
M0120085 BDCIFKPM_00004 2738 3 Oral 0.60 protein_coding synonymous_variant LOW 363A>G Leu121Leu
M0120086 BDCIFKPM_00004 2746 3 Oral 0.60 protein_coding missense_variant MODERATE 355T>C Cys119Arg
M0120087 BDCIFKPM_00004 2987 3 Oral 0.60 protein_coding synonymous_variant LOW 114T>C Asn38Asn
M0120088 BDCIFKPM_00005 3382 4 Oral 0.80 protein_coding missense_variant MODERATE 840G>A Met280Ile
M0120089 BDCIFKPM_00005 3457 3 Oral 0.60 protein_coding missense_variant MODERATE 765A>G Ile255Met
M0120090 BDCIFKPM_00005 3520 3 Oral 0.60 protein_coding synonymous_variant LOW 702T>C Ser234Ser
M0120091 BDCIFKPM_00005 3544 3 Oral 0.60 protein_coding synonymous_variant LOW 678T>C Phe226Phe
M0120092 BDCIFKPM_00005 3679 3 Oral 0.60 protein_coding synonymous_variant LOW 543T>C Asp181Asp
M0120093 BDCIFKPM_00005 3721 3 Oral 0.60 protein_coding synonymous_variant LOW 501T>C Gly167Gly
M0120094 BDCIFKPM_00005 3733 3 Oral 0.60 protein_coding synonymous_variant LOW 489T>C Leu163Leu
M0120095 BDCIFKPM_00005 3744 3 Oral 0.60 protein_coding missense_variant MODERATE 478A>C Ser160Arg
M0120096 BDCIFKPM_00005 3760 3 Oral 0.60 protein_coding synonymous_variant LOW 462A>T Ala154Ala
M0120097 BDCIFKPM_00005 3799 3 Oral 0.60 protein_coding synonymous_variant LOW 423A>G Ser141Ser
M0120098 BDCIFKPM_00005 3808 3 Oral 0.60 protein_coding synonymous_variant LOW 414C>T Gly138Gly
M0120099 BDCIFKPM_00005 3853 3 Oral 0.60 protein_coding synonymous_variant LOW 369T>C Cys123Cys
M0120100 BDCIFKPM_00005 3897 3 Oral 0.60 protein_coding synonymous_variant LOW 325C>T Leu109Leu
M0120101 BDCIFKPM_00005 3945 4 Oral 0.80 protein_coding missense_variant MODERATE 277T>C Cys93Arg
M0120102 BDCIFKPM_00005 4075 3 Oral 0.60 protein_coding synonymous_variant LOW 147T>C Asn49Asn
M0120103 BDCIFKPM_00005 3931 3 Oral 0.60 protein_coding synonymous_variant LOW 291T>C Ser97Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BDCIFKPM_00005 EFC71732.1|GT2 93 3.85e-256 1 373 1 0.9395





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term