Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2386
  Reference Plasmid   1111525849768046_bin.37__k141_15262
  Reference Plasmid Size   3677
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0120857 AJLHHMOF_00001 1753 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -193A>T None
M0120858 AJLHHMOF_00002 1824 3 Oral 0.60 protein_coding synonymous_variant LOW 990G>A Gly330Gly
M0120859 AJLHHMOF_00002 1911 3 Oral 0.60 protein_coding synonymous_variant LOW 903G>A Lys301Lys
M0120860 AJLHHMOF_00002 1922 4 Oral 0.80 protein_coding missense_variant MODERATE 892A>G Lys298Glu
M0120861 AJLHHMOF_00002 1962 3 Oral 0.60 protein_coding synonymous_variant LOW 852G>A Glu284Glu
M0120862 AJLHHMOF_00002 2010 4 Oral 0.80 protein_coding synonymous_variant LOW 804T>A Pro268Pro
M0120863 AJLHHMOF_00002 2061 3 Oral 0.60 protein_coding synonymous_variant LOW 753T>C Pro251Pro
M0120864 AJLHHMOF_00002 2064 3 Oral 0.60 protein_coding synonymous_variant LOW 750T>A Ala250Ala
M0120865 AJLHHMOF_00002 2127 4 Oral 0.80 protein_coding synonymous_variant LOW 687G>A Gln229Gln
M0120866 AJLHHMOF_00002 2160 5 Oral 1.00 protein_coding synonymous_variant LOW 654A>G Leu218Leu
M0120867 AJLHHMOF_00002 2169 3 Oral 0.60 protein_coding synonymous_variant LOW 645A>T Val215Val
M0120868 AJLHHMOF_00002 2199 3 Oral 0.60 protein_coding synonymous_variant LOW 615G>T Ser205Ser
M0120869 AJLHHMOF_00002 2306 5 Oral 1.00 protein_coding missense_variant MODERATE 508A>G Thr170Ala
M0120870 AJLHHMOF_00002 2319 5 Oral 1.00 protein_coding synonymous_variant LOW 495A>G Leu165Leu
M0120871 AJLHHMOF_00002 2583 5 Oral 1.00 protein_coding synonymous_variant LOW 231G>A Ala77Ala
M0120872 AJLHHMOF_00002 2805 5 Oral 1.00 protein_coding missense_variant MODERATE 9T>A Asn3Lys
M0120873 AJLHHMOF_00003 2907 4 Oral 0.80 protein_coding synonymous_variant LOW 606C>T Tyr202Tyr
M0120874 AJLHHMOF_00003 2994 5 Oral 1.00 protein_coding synonymous_variant LOW 519C>T Asn173Asn
M0120875 AJLHHMOF_00003 3012 5 Oral 1.00 protein_coding synonymous_variant LOW 501T>A Gly167Gly
M0120876 AJLHHMOF_00003 3102 4 Oral 0.80 protein_coding synonymous_variant LOW 411C>A Arg137Arg
M0120877 AJLHHMOF_00003 3108 5 Oral 1.00 protein_coding synonymous_variant LOW 405A>G Lys135Lys
M0120878 AJLHHMOF_00003 3138 4 Oral 0.80 protein_coding synonymous_variant LOW 375T>C Ile125Ile
M0120879 AJLHHMOF_00003 3261 4 Oral 0.80 protein_coding synonymous_variant LOW 252A>G Lys84Lys
M0120880 AJLHHMOF_00003 3279 3 Oral 0.60 protein_coding synonymous_variant LOW 234T>A Val78Val
M0120881 AJLHHMOF_00003 3417 4 Oral 0.80 protein_coding synonymous_variant LOW 96T>A Val32Val
M0120882 AJLHHMOF_00003 3504 3 Oral 0.60 protein_coding synonymous_variant LOW 9A>G Val3Val
M0120883 AJLHHMOF_00001 3516 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1956A>G None
M0120884 AJLHHMOF_00001 1709 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -149T>A None
M0120885 AJLHHMOF_00002 2451 3 Oral 0.60 protein_coding synonymous_variant LOW 363C>T Asn121Asn
M0120886 AJLHHMOF_00003 2964 3 Oral 0.60 protein_coding synonymous_variant LOW 549T>A Ala183Ala
M0120887 AJLHHMOF_00003 3057 3 Oral 0.60 protein_coding synonymous_variant LOW 456T>A Ile152Ile
M0120888 AJLHHMOF_00003 3059 3 Oral 0.60 protein_coding missense_variant MODERATE 454A>G Ile152Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term